[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100534361":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":30,"locations":39,"responsibleParty":66,"collaborators":30,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":30,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":30,"enrollmentInfo":77,"targetDuration":30,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":41,"whyStopped":30,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"University of Delaware","OTHER",[8,16,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Identifying and synthesizing high-contrast tactile materials without physical features","EXPERIMENTAL","Beyond the few materials investigators previously identified, it is unknown which materials are useful for creating tactile sensations. Common material properties such as a friction coefficient or hydrophilicity are insufficiently detailed to accurately predict friction forces-the basis of tactile stimuli. The investigators will use expertise in connecting tactile sensations with chemical structure through mechanical testing, theory, and human testing. The investigators' goal is to identify materials that lead to high tactile contrast without relying on physical features. (Tactile contrast is defined by the investigators as large differences in friction which are easily distinguishable by humans during free tactile exploration.)",[13,14,15],"Behavioral: Single bump acuity","Behavioral: Optimal spacing between bumps","Behavioral: Improving signal from a single bump with designer materials",{"label":17,"type":10,"description":18,"interventionNames":19},"Building tactile aids with designer materials for plots, games, and object labeling","Investigators will build static tactile aids with designer materials, i.e., silanes and polymers coatings. These aids will be a mathematical plot, a board game, and simulated money. Investigators will compare the speed, accuracy, and amount of information of hybrid tactile aids made from designer materials and physical features to traditional tactile aids made only with bumps.",[13,14,15],{"label":21,"type":10,"description":22,"interventionNames":23},"Optimal design of bumps and designer materials in tactile aids","Reflecting the lack of standardized methods or benchmarks for tactile technologies, the known limits of tactile sensitivity was narrowed from millimeters, microns, to nanometers within the last 10 years by use of metal wires, wrinkled plastics, and silanes, respectively. Investigators will determine the optimal design of traditional bumps which yields the highest tactile stimulus in the smallest area. Investigators expect to find that current bumps are larger than necessary, and that the same information could be placed into a smaller area (higher information density). Then, investigators will augment bumps with designer materials to increase the tactile stimulus from a bump, thereby permitting even smaller bumps to increase information density. Beyond optimal design methods, the investigators' quantitative methods, enabled by making the mechanical stimulus the dependent variable, also serve as benchmarks between tactile aids.",[13,14,15],[25,31,35],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","Single bump acuity","Investigators will design bumps of varying heights, spacings, diameters, and bump shapes (rounded top, flat top, angled top) which give a precise amount of mechanical stimulus to the finger. Subjects will be asked if they could notice a bump on the surface and instructed to make the judgment quickly (\\\u003C2 seconds). A psychometric curve, with a standard braille bump serving as the positive, \\~100% success rate control, will be constructed",[17,9,21],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Optimal spacing between bumps","Investigators will fabricate and characterize two bumps of varying widths (ranging from 150 μm to 3 times the bump width, based on fabrication resolution available in commercial tactile aid machines). Subjects will be asked to run their finger across the two bumps (two bumps always form a line, so investigators do not need to ask subjects to orient their fingers) quickly and asked if they felt one bump or two.",[17,9,21],{"type":26,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Improving signal from a single bump with designer materials","Investigators will coat single bumps with our designer materials (with alkyl and amino functional groups) to improve the mechanical stimuli from a single bump. Subjects will then be asked to perform a similar experiment as the \"single bump acuity\" test and the \"optimal spacing between bumps\" test. (\"can you notice the bump?\" or \"did you feel one or two bumps\").",[17,9,21],[40],{"facility":5,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Newark","Delaware","19711","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-75.74966,39.68372,{"lat":51,"lon":50},[54,59,63],{"name":55,"role":56,"phone":57,"phoneExt":30,"email":58},"Charles Dhong","CONTACT","302-831-2828","cdhong@udel.edu",{"name":60,"role":56,"phone":61,"phoneExt":30,"email":62},"Cynthia Papettas","3022796766","cpap@Udel.edu",{"name":64,"role":65,"phone":30,"phoneExt":30,"email":30},"Charles Dhong, PhD","PRINCIPAL_INVESTIGATOR",{"type":67,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR","100534361","testing-tactile-aids-with-blind-subjects-100534361",false,"NCT06237829","Testing Tactile Aids With Blind Subjects","Inclusion Criteria:\n\n* Visual Impairment: Participants should be blind or visually impaired for greater than 10 years, either congenitally or acquired.\n* Tactile Aid Usage: Participants must use tactile aids regularly.\n* Mathematical Knowledge: Participants should have a basic understanding of mathematical plots, equivalent to at least high school geometry.\n\nExclusion Criteria:\n\n\\- Limb Conditions: Participants with amputations or outer extremity conditions affecting hand use will be excluded.",true,"ALL","16 Years",{"count":78,"type":79},100,"ESTIMATED","INTERVENTIONAL",[82],"NA","The objective of this project is to create richer tactile aids by using materials chemistry to create tactile sensations in tactile aids, as an alternative to traditional physical bumps, lines, or textures. These materials are commonly used in household products, but have not yet been used to enrich tactile aids. Successful outcomes are primarily the accuracy with which low vision or blind subjects identify objects made from tactile coatings versus traditional tactile aids. Other outcomes include time to completion of the task, or the number of distinctive categories that participants can identify.",[85,86],"Vision, Low","Blindness",[88],"Tactile Aid","2024-03-11",{"date":91,"type":92},"2024-03-13","ACTUAL",{"date":94,"type":92},"2021-09-01",{"date":96,"type":79},"2027-12",{"name":5,"class":6},1]