[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611794":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":28,"responsibleParty":47,"collaborators":18,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":18,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":71,"overallStatus":89,"whyStopped":18,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"King's College London","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cannabis for Psychosis Intervention + Treatment as Usual","EXPERIMENTAL","The CCP intervention consists of two main components:\n\n1. one-to-one weekly sessions: offered both face to face and online to meet the patient preference. Patients can change the meeting modality at any point to suit their needs (e.g. transport difficulties, family commitments, or mental state). The CCP intervention uses a combination of evidence-based psychosocial interventions (PSIs) tailored to each patient's needs. Patients are offered on average 12 (SD 4.2) weeks sessions, for a maximum of 60 minutes\n2. an online PEER group is facilitated by a senior member of CCP staff and moderated by two PEER mentors with lived experience of psychosis and cannabis use.",[13],"Other: CCP Intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Treatment as Usual \u002F Waiting List","NO_INTERVENTION","Participants continue Treatment as Usual from their clinical team while on a 16-week waiting list for the CCP intervention.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"CCP Intervention","1. one-to-one weekly sessions: offered both face to face and online to meet the patient preference. Patients can change the meeting modality at any point to suit their needs (e.g. transport difficulties, family commitments, or mental state). The CCP intervention uses a combination of evidence-based psychosocial interventions (PSIs) tailored to each patient's needs. Patients are offered on average 12 (SD 4.2) weeks sessions, for a maximum of 60 minutes.\n2. an online PEER group is facilitated by a senior member of CCP staff and moderated by two PEER mentors with lived experience of psychosis and cannabis use.",[9],[25,26,27],"psychosocial intervention","motivational interviewing","cognitive behavioral therapy",[29],{"facility":30,"status":18,"city":31,"state":18,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Marina House","London","SE5 8RZ","United Kingdom","UK",{"type":36,"coordinates":37},"Point",[38,39],-0.12574,51.50853,{"lat":39,"lon":38},[42],{"name":43,"role":44,"phone":45,"phoneExt":18,"email":46},"Marta Di Forti","CONTACT","+44 7970211938","marta.diforti@kcl.ac.uk",{"type":48,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100611794","testing-the-efficacy-of-the-cannabis-clinic-for-patients-with-psychosis-ccp-intervention-for-cannabis-use-reductioncessation-in-patients-with-first-episode-psychosis-fep-100611794",false,"NCT07245212","Testing the Efficacy of the Cannabis Clinic for Patients With Psychosis (CCP) Intervention for Cannabis Use Reduction\u002FCessation in Patients With First Episode Psychosis (FEP)","Testing the Efficacy of the Cannabis Clinic for Patients With Psychosis (CCP) Intervention for Cannabis Use Reduction\u002FCessation in Patients With First Episode Psychosis","CCP RCT","Inclusion Criteria:\n\n* First episode psychosis Community Mental Health teams receiving care under of SLaM Early Intervention for Psychosis Adult Mental Health Teams\n* CUDIT≥9 (Dependent on Cannabis)\n* age=18 to 65 years old ( age range of adult psychiatric services)\n* Capacity to give informed consent, as assessed by clinical teams\n\nExclusion Criteria:\n\n* Lack capacity to consent\n* High levels of suicidal ideation, judged by clinical team\n\n  -≥2 days\u002Fweek frequency use of any other illicit drug\n* Participation in any other current intervention trial\n* In active crises and\u002For expressing suicidal ideations","ALL","18 Years","65 Years",{"count":61,"type":62},80,"ESTIMATED","INTERVENTIONAL",[65],"NA","People suffering from psychosis who use cannabis experience more relapses, long and compulsory admissions, with huge costs to the individual, families and health services. The Cannabis Clinic for Psychosis (CCP) was developed to respond to this clinical need. A published review of the CCP's intervention showed its safety and efficacy in supporting people suffering from psychosis with reducing their cannabis use. Nevertheless, for the CCP model of care to be applied widely and benefit a larger clinical population, its intervention needs to be tested in a Randomised Control Trial (RCT). The proposed CCP RCT is a waiting list randomised controlled trial that aims to evaluate the clinical efficacy of the existing CCP intervention. Participants will be adults currently under the care of South London and Maudsley (SLaM) Early Intervention Teams for first onset psychosis, who are dependent on cannabis and who express an intention to reduce or stop their use. The RCT primary outcome will measure changes in all participants' cannabis use. Participants will be randomised to either the intervention group or the waiting list control group receiving Treatment As Usual (TAU). The CCP intervention comprises 12 weekly (+\u002F- 4 weeks) one-to-one sessions, with optional participation in a weekly online peer group. Sessions are delivered by trained clinicians and include evidence-based psychosocial techniques, including Motivational Interviewing (MI), Cognitive Behavioural Therapy (CBT), SMART goal settings and support for co-occurring tobacco use. The treatment is non-pharmacological and administered via participant-led approach that accommodates online or face-to-face sessions to meet the patient preference. Qualitative data from the recent CCP proof of concept paper indicate that the flexibility in allowing patients choice on the session's modality (online\u002Fface to face, hybrid) increased and maintained engagement.\n\nThe study is fully funded by the Maudsley Charity and due to last 30 months from the start of recruitment.",[68,69,70],"Psychosis","Cannabis Use Disorder","First Episode Psychosis (FEP)",[69,68,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88],"First Episode Psychosis","Cannabis Cessation","Cannabis","Reduction","Cessation","Psychosocial Intervention","Psychosocial","Intervention","Cognitive Behavioural Therapy","Motivational Interviewing","Randomised Controlled Trial","Early Intervention in Psychosis","Cannabis Clinic for Psychosis","psychoeducation","peer support","flexibility","personalised","NOT_YET_RECRUITING","2025-11-20",{"date":92,"type":93},"2025-11-24","ACTUAL",{"date":95,"type":62},"2025-12-01",{"date":97,"type":62},"2028-11-30",{"name":5,"class":6},1]