[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100441580":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":28,"responsibleParty":46,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"University of Washington","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Phase 1",null,"51 subjects with serum levels of testosterone, free testosterone, and sex hormone binding globulin as well as the SpCuV from the cultures obtained in clinic, immediately pre-operative skin cultures, and incised wound cultures.",{"label":13,"type":10,"description":14,"interventionNames":10},"Phase 2","Subjects enrolled to help determine if preoperative serum testosterone levels are associated with risk for shoulder PJI in patients undergoing primary shoulder arthroplasty and if preoperative serum testosterone levels are predictive of bacterial load of deep tissue cultures taken at the time of revision shoulder arthroplasty in patients undergoing primary shoulder arthroplasty.",[16],{"name":17,"affiliation":5,"role":18},"Jason E Hsu, MD","PRINCIPAL_INVESTIGATOR",[20,24],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","330-883-8829","jehsu@uw.edu",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Anastasia Whitson, BS","206-755-7847","whitsa@uw.edu",[29],{"facility":5,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Seattle","Washington","98195","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-122.33207,47.60621,{"lat":40,"lon":39},[43,45],{"name":44,"role":21,"phone":10,"phoneExt":10,"email":23},"Jason Hsu, MD",{"name":25,"role":21,"phone":10,"phoneExt":10,"email":27},{"type":18,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Jason Hsu","Associate Professor, School of Medicine","100441580","testosterone-levels-and-cutibacterium-100441580",false,"NCT05030220","Testosterone Levels and Cutibacterium","Association Between Serum Testosterone Levels and Cutibacterium Culture Positivity During Shoulder Arthroplasty","Phase 1 Inclusion Criteria:\n\n* Patients having elective shoulder arthroplasty\n\nPhase 1 Exclusion Criteria:\n\n* history of shoulder septic arthritis\n* antibiotic use within 3 months prior to surgery\n* recent treatment for acne\n* Lacked fluency in English\n\nPhase 2 Inclusion Criteria:\n\n* Patients having elective shoulder arthroplasty\n\nPhase 2 Exclusion Criteria:\n\n* Lacked fluency in English","ALL","18 Years","89 Years",{"count":60,"type":61},300,"ESTIMATED","OBSERVATIONAL","Phase 1: In 51 patients undergoing shoulder arthroplasties, total serum testosterone, free testosterone and sex hormone binding globulin levels obtained in the clinic before surgery were correlated with the levels of Cutibacterium on the skin in clinic, in the operating room prior to surgery, and in the skin incision.\n\nPhase 2: The investigators wish to determine if preoperative serum testosterone levels are associated with risk for shoulder PJI (periprosthetic joint infection) in patients undergoing primary shoulder arthroplasty. Also to determine if preoperative serum testosterone levels are predictive of bacterial load of deep tissue cultures taken at the time of revision shoulder arthroplasty in patients undergoing primary shoulder arthroplasty.",[65],"Arthroplasty, Replacement, Shoulder",[67,68,69],"Testosterone","Cutibacterium","Shoulder Arthroplasty","2025-03-25",{"date":72,"type":73},"2025-03-30","ACTUAL",{"date":75,"type":73},"2020-07-01",{"date":77,"type":61},"2027-01-01",{"name":5,"class":6},1]