[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632321":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":39,"locations":44,"responsibleParty":60,"collaborators":10,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":10,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":10,"enrollmentInfo":73,"targetDuration":10,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":47,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Non-survivors",null,"Patients who die in hospital",[13,14,15],"Diagnostic Test: Tetanus Severity Score (TSS)","Diagnostic Test: Philips Score","Diagnostic Test: Dakar Score",{"label":17,"type":10,"description":18,"interventionNames":19},"Survivors","Patients who survive to hospital discharge",[13,14,15],[21,26,30],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"DIAGNOSTIC_TEST","Tetanus Severity Score (TSS)","The Tetanus Severity Score (TSS) is calculated for each patient by the investigator using the required data as documented in the medical records at admission",[9,17],{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"Philips Score","The Philips Score is calculated for each patient by the investigator using the required data as documented in the medical records at admission",[9,17],{"type":22,"name":31,"description":32,"armGroupLabels":33,"otherNames":10},"Dakar Score","The Dakar Score is calculated for each patient by the investigator using the required data as documented in the medical records at admission",[9,17],[35],{"name":36,"affiliation":37,"role":38},"Sameh M Hakim, MD","Ain Shams University Faculty of Medicine","STUDY_DIRECTOR",[40],{"name":36,"role":41,"phone":42,"phoneExt":10,"email":43},"CONTACT","+202 26900073","hakimsm@med.asu.edu.eg",[45],{"facility":46,"status":47,"city":48,"state":10,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Ain Shams University Hospitals & Demanhour Fever Hospital","RECRUITING","Cairo","11341","Egypt","EG",{"type":53,"coordinates":54},"Point",[55,56],31.24967,30.06263,{"lat":56,"lon":55},[59],{"name":36,"role":41,"phone":42,"phoneExt":10,"email":43},{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Sameh M. Hakim","Professor of Anesthesiology, Intensive Care and Pain Management","100632321","tetanus-severity-score-for-prediction-of-mortality-in-manifest-tetanus-100632321",false,"NCT07512167","Tetanus Severity Score for Prediction of Mortality in Manifest Tetanus","Comparison of Three Scoring Systems for Prediction of Mortality in Patients Admitted to the Intensive Care Unit With Manifest Tetanus","Inclusion criteria:\n\n* Adults (age 18 years old or more).\n* Any sex (male or female), regardless of gender identity.\n* Diagnosis of manifest tetanus according to the WHO criteria (https:\u002F\u002Fwww.who.int\u002Fnews-room\u002Ffact-sheets\u002Fdetail\u002Ftetanus), that is the presence of one or both of the following criteria with or without the history of specific wound or injury:\n\n  * Sustained spasm of the facial muscles in which person appears grinning.\n  * Painful muscular contractions\n\nExclusion criteria:\n\n* Age \\\u003C 18 years.\n* Absent criteria of manifest tetanus, as per the WHO criteria (https:\u002F\u002Fwww.who.int\u002Fnews-room\u002Ffact-sheets\u002Fdetail\u002Ftetanus).\n* Incomplete medical record with missing data required to calculate the Tetanus Severity Score, Philips Score, or Dakar score.\n* Incomplete medical record with missing data regarding the primary outcome measure (survival to hospital discharge or in-hospital mortality).","ALL","18 Years",{"count":74,"type":75},115,"ESTIMATED","OBSERVATIONAL","Three scoring systems will be applied to patients suffering from manifest tetanus and will be related to mortality.",[79],"Tetanus, Manifest",[81],"Tetanus, Tetanus Severity Score","2026-05-26",{"date":84,"type":85},"2026-05-28","ACTUAL",{"date":87,"type":85},"2026-04-15",{"date":89,"type":75},"2026-06-15",{"name":5,"class":6},1]