[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555737":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":45,"centralContacts":49,"locations":35,"responsibleParty":58,"collaborators":60,"id":106,"slug":107,"hasResults":108,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":35,"eligibilityCriteria":112,"healthyVolunteers":108,"sex":113,"minAge":114,"maxAge":115,"enrollmentInfo":116,"targetDuration":35,"studyType":119,"phases":120,"briefSummary":122,"conditions":123,"keywords":126,"overallStatus":133,"whyStopped":35,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":35},{"fullName":5,"class":6},"Changhai Hospital","OTHER",[8,14,19,25],{"label":9,"type":10,"description":11,"interventionNames":12},"TXI (Group A)","EXPERIMENTAL","Arm undergoing colonoscopy with TXI",[13],"Procedure: TXI (Group A)",{"label":15,"type":10,"description":16,"interventionNames":17},"TXI followed by WLI (Group B)","Arm undergoing initial inspection under TXI first, followed by second inspection with WLI",[18],"Procedure: TXI followed by WLI (Group B)",{"label":20,"type":21,"description":22,"interventionNames":23},"WLI (Group C)","ACTIVE_COMPARATOR","Arm undergoing normal colonoscopy with WLI",[24],"Procedure: WLI (Group C)",{"label":26,"type":21,"description":27,"interventionNames":28},"WLI followed by TXI (Group D)","Arm undergoing initial inspection under WLI first, followed by second inspection with TXI",[29],"Procedure: WLI followed by TXI (Group D)",[31,36,39,42],{"type":32,"name":9,"description":33,"armGroupLabels":34,"otherNames":35},"PROCEDURE","Patients in Group A will undergo colonoscopy with TXI.",[9],null,{"type":32,"name":15,"description":37,"armGroupLabels":38,"otherNames":35},"Patients in group B will first undergo colonoscopy with TXI and every polyp found should be removed. Then switch to WLI for a second withdrawal to detect lesions that were not observed the first time.",[15],{"type":32,"name":20,"description":40,"armGroupLabels":41,"otherNames":35},"Patients in Group C will undergo colonoscopy with WLI.",[20],{"type":32,"name":26,"description":43,"armGroupLabels":44,"otherNames":35},"Patients in group D will first undergo colonoscopy with WLI and every polyp found should be removed. Then switch to TXI for a second withdrawal to detect lesions that were not observed the first time.",[26],[46],{"name":47,"affiliation":5,"role":48},"Zhaoshen Li, MD","PRINCIPAL_INVESTIGATOR",[50,54],{"name":47,"role":51,"phone":52,"phoneExt":35,"email":53},"CONTACT","86-021-31161365","li.zhaoshen@hotmail.com",{"name":55,"role":51,"phone":56,"phoneExt":35,"email":57},"Yu Bai, MD","86-021-31161335","baiyu1998@hotmail.com",{"type":59,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR",[61,63,65,68,70,72,74,76,78,80,82,84,86,88,90,92,94,96,98,100,102,104],{"name":62,"class":6},"The First Affiliated Hospital of Dalian Medical University",{"name":64,"class":6},"The Second Hospital of Hebei Medical University",{"name":66,"class":67},"The Second Affiliated Hospital of Guangzhou University of Chinese Medicine","UNKNOWN",{"name":69,"class":6},"Huadong Hospital",{"name":71,"class":6},"Shanghai 6th People's Hospital",{"name":73,"class":6},"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine",{"name":75,"class":6},"The General Hospital of Eastern Theater Command",{"name":77,"class":6},"Jiangsu Provincial People's Hospital",{"name":79,"class":6},"First People's Hospital of Hangzhou",{"name":81,"class":6},"Wenzhou Central Hospital",{"name":83,"class":6},"The First Affiliated Hospital of Nanchang University",{"name":85,"class":67},"Shanxi Coal Center Hospital",{"name":87,"class":6},"Dalian Municipal Central Hospital",{"name":89,"class":6},"Seventh Medical Center of PLA Army General Hospital",{"name":91,"class":6},"Henan Provincial People's Hospital",{"name":93,"class":6},"Zunyi Medical College",{"name":95,"class":67},"Shandong Second People's Hospital",{"name":97,"class":6},"The Third People's Hospital of Chengdu",{"name":99,"class":6},"Lanzhou University Second Hospital",{"name":101,"class":67},"The Third People's Hospital of Jingdezhen",{"name":103,"class":67},"Fudan University Attached Tumor Hospital",{"name":105,"class":6},"Qingyuan People's Hospital","100555737","texture-and-colour-enhancement-imaging-in-improving-detection-and-miss-rate-of-premalignant-lesions-100555737",false,"NCT06515977","Texture and Colour Enhancement Imaging in Improving Detection and Miss Rate of Premalignant Lesions","Impact of Texture and Color Enhancement Imaging on Detection and Miss Rate of Premalignant Lesions: A Multicentre, Randomized, Tandem Trial","Inclusion Criteria:\n\npatients aged 45-85 years and scheduled for screening colonoscopy who provided written informed consent\n\nExclusion Criteria:\n\nSurveillance, diagnostic or therapeutic colonoscopy\n\nPatients with an already known or suspected colorectal tumour\n\nPatients with alarming symptoms and signs, including haematochezia, melena, weight loss or anaemia without specific causes, an abdominal mass and positive digital rectal examination\n\nPregnant or lactating women\n\nPatients with gastrointestinal tract obstruction\n\nPatients with inflammatory bowel diseases, hereditary CRC syndromes or serrated polyposis syndrome\n\nPatients with abnormal blood coagulation or taking antiplatelets or anticoagulants within 7 days before colonoscopy\n\nPatients with failed cecal intubation\n\nPatients with poor bowel preparation quality that necessitated a second bowel preparation\n\nPatients with a history of colonic resection","ALL","45 Years","85 Years",{"count":117,"type":118},2964,"ESTIMATED","INTERVENTIONAL",[121],"NA","Texture and Color Enhancement Imaging (TXI) is a newly developed image-enhancing endoscopy technology that has show potential in improving detection of colorectal lesions. This multicenter, randomized, tandem trial is aimed at evaluating whether TXI is superior to WLI endoscopy in terms of diagnosis of premalignant lesions.",[124,125],"Adenoma","Sessile Serrated Adenoma",[127,128,129,130,131,132],"texture and color enhancement imaging","colonoscopy","adenoma detection rate","sessile serrated lesion detection rate","adenoma miss rate","sessile serrated lesion miss rate","NOT_YET_RECRUITING","2024-07-17",{"date":136,"type":137},"2024-07-23","ACTUAL",{"date":139,"type":118},"2024-08-01",{"date":141,"type":118},"2025-08-01",{"name":5,"class":6}]