[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560400":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":43,"centralContacts":47,"locations":53,"responsibleParty":94,"collaborators":97,"id":103,"slug":104,"hasResults":105,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":34,"eligibilityCriteria":109,"healthyVolunteers":110,"sex":111,"minAge":112,"maxAge":113,"enrollmentInfo":114,"targetDuration":34,"studyType":117,"phases":118,"briefSummary":120,"conditions":121,"keywords":123,"overallStatus":56,"whyStopped":34,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":136},{"fullName":5,"class":6},"University of Massachusetts, Worcester","OTHER",[8,16,20,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard PrEP counseling, mHC, and FRESH content","EXPERIMENTAL","Participants in this arm will receive standard PrEP counseling, followed by four mHC sessions and six FRESH sessions to reduce stigma and increase utilization of HIV prevention services.",[13,14,15],"Behavioral: Mobile Healthy Choices (mHC)","Behavioral: Finding Respect and Ending Stigma around HIV (FRESH)","Behavioral: Standard PrEP Counseling",{"label":17,"type":10,"description":18,"interventionNames":19},"Standard PrEP counseling and mHC","Participants in this arm will receive standard PrEP counseling, followed by four mHC sessions to reduce stigma and increase utilization of HIV prevention services.",[13,15],{"label":21,"type":10,"description":22,"interventionNames":23},"Standard PrEP counseling and FRESH content","Participants in this arm will receive standard PrEP counseling, followed by six FRESH sessions to reduce stigma and increase utilization of HIV prevention services.",[14,15],{"label":25,"type":10,"description":26,"interventionNames":27},"Standard PrEP counseling","Participants in this arm will receive the standard PrEP counseling.",[15],[29,35,39],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"BEHAVIORAL","Mobile Healthy Choices (mHC)","mHC is a four-session, 20-minute, motivational interviewing-based intervention, which will be delivered on the CIAS platform. It will be tailored to participants' responses given during the interaction in the intervention. In the first two sessions, the (virtual) counselor will motivate participants to overcome stigma and utilize HIV prevention services by using tailored motivational interviewing strategies, develop an individualized change goal based on their readiness, and provide cognitive behavioral strategies. In the last two sessions, the counselor will review the change plan, monitor progress, and provide support for sustained behavioral change. The sessions will occur within three months after baseline.",[17,9],null,{"type":30,"name":36,"description":37,"armGroupLabels":38,"otherNames":34},"Finding Respect and Ending Stigma around HIV (FRESH)","FRESH content includes six 10-15 minute sessions with interactive, culturally sensitive multimedia modules, which will be delivered on the CIAS platform. The content will aim to improve self-efficacy, reduce intersectional stigmas and promote HIV preventative behaviors. The sessions will occur within three months after baseline.",[21,9],{"type":30,"name":40,"description":41,"armGroupLabels":42,"otherNames":34},"Standard PrEP Counseling","All participants will receive one-on-one, face to face counseling from focusing on sexual and behavioral risk assessment for HIV\u002FSTIs, risk reduction, and HIV prevention. For those not on PrEP, the sessions will focus on risk perception, awareness of PrEP, and facilitators and barriers to PrEP access. For those on PrEP, the sessions will focus on adherence. The counseling will be provided at baseline, 3 months, and 6 months.",[25,21,17,9],[44],{"name":45,"affiliation":5,"role":46},"Bo Wang, PhD","PRINCIPAL_INVESTIGATOR",[48],{"name":49,"role":50,"phone":51,"phoneExt":34,"email":52},"Deogwoon Kim, PhD","CONTACT","586-703-4899","Deogwoon.Kim13@umassmed.edu",[54,75,84],{"facility":55,"status":56,"city":57,"state":34,"zip":34,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"Institute of HIV Research and Innovation","RECRUITING","Bangkok","Thailand","TH",{"type":61,"coordinates":62},"Point",[63,64],100.50144,13.75398,{"lat":64,"lon":63},[67,71,72],{"name":68,"role":50,"phone":69,"phoneExt":34,"email":70},"Nittaya Phanuphak","6621605371","nittaya.p@ihri.org",{"name":68,"role":46,"phone":34,"phoneExt":34,"email":34},{"name":73,"role":74,"phone":34,"phoneExt":34,"email":34},"Rena Janamnuaysook","SUB_INVESTIGATOR",{"facility":76,"status":56,"city":57,"state":34,"zip":34,"country":58,"countryCode":59,"cosmosGeoPoint":77,"geoPoint":79,"contacts":80},"Rainbow Sky Association of Thailand",{"type":61,"coordinates":78},[63,64],{"lat":64,"lon":63},[81],{"name":82,"role":50,"phone":34,"phoneExt":34,"email":83},"Phubet Panpet","phubet.p@rsat.info",{"facility":85,"status":56,"city":57,"state":34,"zip":34,"country":58,"countryCode":59,"cosmosGeoPoint":86,"geoPoint":88,"contacts":89},"SWING Foundation",{"type":61,"coordinates":87},[63,64],{"lat":64,"lon":63},[90],{"name":91,"role":50,"phone":92,"phoneExt":34,"email":93},"Surang Janyam","6602632950","director.swingfoundation@gmail.com",{"type":46,"investigatorFullName":95,"investigatorTitle":96,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"Bo Wang","Professor",[98,101],{"name":99,"class":100},"National Institute of Mental Health (NIMH)","NIH",{"name":102,"class":6},"Institute of HIV Research and Innovation Foundation, Thailand","100560400","thailand-hiv-and-stigma-reduction-study-100560400",false,"NCT06576648","Thailand HIV and Stigma Reduction Study","Optimizing Mobile Interventions to Overcome Stigma and Promote HIV Prevention","Aim 1 (Formative Research and Beta-Testing) Transgender women\n\nInclusion Criteria:\n\n* Ages between 18 and 29 years\n* Male sex at birth\n* Self-identifies as women, transgender women or culturally identifies with the female spectrum\n* Laboratory-confirmed HIV-negative status\n* Self-reported recent history of condomless sex\n* Able to understand, read and speak Thai\n* Either not started PrEP or currently on PrEP but not adherent (taking ≤3 pills\u002Fweek) in the past month.\n\nExclusion Criteria:\n\n* Have a serious cognitive or psychiatric problem compromising ability to provide informed consent\n* Have active suicidal ideation or major mental illness at the time of interview (these patients will be referred for treatment)\n* Laboratory or clinical findings that would preclude PrEP initiation (e.g., decreased creatinine clearance)\n* Currently enrolled in another HIV intervention study.\n\nHealthcare providers Inclusion criteria\n\n* Age 18 or above\n* Has provided HIV prevention or treatment services for TGW for at least one year Exclusion criteria\n* None\n\nAim 2 (Pilot RCT) Transgender women Inclusion criteria\n\n* Ages between 18 and 29 years\n* Male sex at birth\n* Self-identifies as women, transgender women or culturally identifies with the female spectrum\n* Laboratory-confirmed HIV-negative status\n* Self-reported recent history of condomless sex\n* Able to understand, read and speak Thai\n* Either not started PrEP or currently on PrEP but not adherent (taking ≤3 pills\u002Fweek) in the past month.\n\nExclusion criteria\n\n* Have a serious cognitive or psychiatric problem compromising ability to provide informed consent\n* Have active suicidal ideation or major mental illness at the time of interview (these patients will be referred for treatment)\n* Laboratory or clinical findings that would preclude PrEP initiation (e.g., decreased creatinine clearance)\n* Currently enrolled in another HIV intervention study.",true,"MALE","18 Years","29 Years",{"count":115,"type":116},154,"ESTIMATED","INTERVENTIONAL",[119],"NA","This project will develop a multi-component, technology-delivered intervention designed to reduce HIV and intersectional stigma and improve the use of HIV pre-exposure prophylaxis (PrEP) among HIV-negative Thai vulnerable emerging adults (18-29 years).",[122],"Pre-Exposure Prophylaxis",[122,124,125,126],"HIV Prevention","mHealth","Stigma","2025-09-03",{"date":129,"type":130},"2025-09-08","ACTUAL",{"date":132,"type":130},"2025-02-20",{"date":134,"type":116},"2027-08-14",{"name":5,"class":6},3]