[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100430403":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":25,"responsibleParty":38,"collaborators":41,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":10,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Rigshospitalet, Denmark","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Cross-sectional cohort",null,"Healthy children and adolescents from twenty-five selected schools in the metropolitan area",{"label":13,"type":10,"description":14,"interventionNames":10},"Longitudinal cohort","Cases with first-time diagnoses of extremely early puberty within the period 1995-2019 in the National Patient Registry and five randomly selected references drawn from the general background population in the Danish Civil registry (CPR) matched on age and sex for each case",[16],{"name":17,"affiliation":18,"role":19},"Anders Juul, PhD, DMSc","Rigshospitalet, Department of Growth and Reproduction","PRINCIPAL_INVESTIGATOR",[21],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},"CONTACT","+45 35 45 13 77","anders.juul@regionh.dk",[26],{"facility":18,"status":27,"city":28,"state":10,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":10},"RECRUITING","Copenhagen","2100","Denmark","DK",{"type":33,"coordinates":34},"Point",[35,36],12.56553,55.67594,{"lat":36,"lon":35},{"type":19,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Anders Juul","Anders Juul, Rigshospitalet, Denmark",[42,45],{"name":43,"class":44},"Environmental Protection Agency (EPA)","FED",{"name":46,"class":6},"European Commission","100430403","the-3rd-copenhagen-puberty-study-100430403",false,"NCT04884620","The 3rd COPENHAGEN Puberty Study","The COPENHAGEN School Study. Normal Pubertal Development in Youth 2021 and Long-term Disease and Death Risk After Extremely Early Puberty","Inclusion Criteria:\n\n* Healthy children and adolescents\n\nExclusion Criteria:\n\n* In case of acute disease, cancer, cancer therapy, or chronic disease (History of malignant disease, chemotherapy or radiation, cystic fibrosis, juvenile rheumatoid arthritis, systemic lupus erythematosus, sickle cell disease, thalassemia, chronic renal disease or known numerical chromosome aberration)\n* Non-Caucasian",true,"ALL","5 Years","19 Years",{"count":59,"type":60},3000,"ESTIMATED","OBSERVATIONAL","The COPENHAGEN School Study is a combined cross-sectional and longitudinal study of healthy Danish school children. This study will by clinical examinations and withdrawal of blood samples investigate whether age of pubertal onset is continuing to decline in Denmark over the past 15 years. Furthermore, we will investigate the mechanism driving earlier onset of puberty and the long term health risks of extremely early puberty using Danish registry data",[64,65],"Puberty","Puberty, Precocious","2024-01-09",{"date":68,"type":69},"2024-01-10","ACTUAL",{"date":71,"type":69},"2023-01-01",{"date":73,"type":60},"2056-12-31",{"name":5,"class":6},1]