[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597386":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":44,"responsibleParty":59,"collaborators":26,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":26,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":84,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Royal College of Surgeons, Ireland","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Partial Calcanectomy with Cerament G","EXPERIMENTAL","Patients will undergo partial calcanectomy with the application of Cerament G.",[13],"Device: Cerament G",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Partial Calcanectomy","ACTIVE_COMPARATOR","Patients will undergo partial calcanectomy with standard antibiotic therapy.",[19],"Other: Standard Surgical Managment",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Cerament G","Partial Calcanectomy plus cerament G",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Standard Surgical Managment","Partial Calcanectomy as standard of care",[15],[32],{"name":33,"affiliation":34,"role":35},"James Walsh","Beaumont Hospital","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+353 1 809 3344","james@walshortho.ie",{"name":42,"role":38,"phone":26,"phoneExt":26,"email":43},"Ramy Elkady","drramyelkady86@hotmail.co.uk",[45],{"facility":46,"status":26,"city":47,"state":26,"zip":26,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"University Hospital Galway","Galway","Ireland","IE",{"type":51,"coordinates":52},"Point",[53,54],-9.05095,53.27245,{"lat":54,"lon":53},[57],{"name":58,"role":38,"phone":26,"phoneExt":26,"email":26},"Stewart Walsh",{"type":60,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100597386","the-achills-trial-application-of-cerament-in-heel-infection-for-lower-limb-salvage-100597386",false,"NCT07057817","The ACHILLS Trial; Application of Cerament in Heel Infection for Lower Limb Salvage","Randomised Controlled Trial Comparing Partial Calcanectomy Plus Local Application Antibiotic Impregnated Bone Graft Substitute for Calcaneal Osteomyelitis vs Partial Calcanectomy Alone (The ACHILLS Trial)","ACHILLS","Inclusion Criteria:\n\n* 18 and over\n* Undergoing partial calcanectomy\n* Patients with Type1 or Type 2 Diabetes\n* Patients will be stratified by Pulse status and eGFR\n\nExclusion Criteria:\n\n* Patients unfit for surgery\n* Patients unable to provide informed consent\n* Patients with overwhelming sepsis that require major amputation\n* Patients with hypersensitivity to aminoglycosides\n* Pre-existing calcium metabolism disorder\n* Severe renal impairment\n* Patients in whom major limb amputation is deemed inevitable by the treating physician","ALL","18 Years",{"count":72,"type":73},30,"ESTIMATED","INTERVENTIONAL",[76],"NA","The ACHILLS Trial is a multicentre randomised controlled feasibility study comparing partial calcanectomy with and without the use of an antibiotic-impregnated bone graft substitute (Cerament G) for treating calcaneal osteomyelitis, specifically on wound healing rates, re-infection, and overall efficacy in a sample of 30 patients over a one-year period.",[79,80,81],"Osteomyelitis","Diabetes","Calcanectomy",[81,83],"Eq5d5l","NOT_YET_RECRUITING","2025-07-30",{"date":87,"type":88},"2025-08-03","ACTUAL",{"date":90,"type":73},"2025-07-25",{"date":92,"type":73},"2026-07-25",{"name":5,"class":6},1]