[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596589":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":37,"centralContacts":41,"locations":48,"responsibleParty":72,"collaborators":46,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":46,"eligibilityCriteria":80,"healthyVolunteers":77,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":46,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":50,"whyStopped":46,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"University of Washington","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Effective portable air cleaner (HEPA)","EXPERIMENTAL","During the baseline home visit, a Winix 9800 air cleaner is installed in the child's bedroom and paired with data logging energy use monitor as well as air quality monitor. Households randomized to the intervention group receive an air cleaner with a pre-filter, carbon filter, and with the HEPA air filter pre-installed.",[13],"Device: Portable air cleaner with HEPA filter",{"label":15,"type":16,"description":17,"interventionNames":18},"Control portable air cleaner (less effective).","SHAM_COMPARATOR","During the baseline home visit, a Winix 9800 air cleaner is installed in the child's bedroom. In the sham group, the Winix 9800 true HEPA filter and activated carbon filter which were removed via an internal modification not visible to the user. The air cleaner still included a washable fine mesh pre-filter that captures large airborne particles. Households randomized to the sham group receive an air cleaner with only the pre-filter and without the carbon filter, and HEPA air filter.",[19],"Device: Less effective portable air cleaner (no HEPA)",[21,30],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Portable air cleaner with HEPA filter","The Winix 9800 is a true HEPA air cleaner that has been AHAM (Association of Home Appliance Manufacturers) Verifide® for rooms that are 500 square feet in size. The air cleaner has a washable fine mesh pre-filter that captures large airborne particles, an activated carbon filter that reduces volatile organic compounds and odors, and a true HEPA filter that captures 99.99% of airborne allergens as small as 0.003 microns in size.",[9],[27,28,29],"HEPA","Portable air cleaner","Air Filter",{"type":22,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Less effective portable air cleaner (no HEPA)","Winix 9800 air cleaner, with data logging energy use monitor is installed in the child's bedroom. In the sham group, the Winix 9800 true HEPA filter and activated carbon filter were removed. This was an internal modification and not visible to the user. The air cleaner still included a washable fine mesh pre-filter that captures large airborne particles.",[15],[35,36],"portable air cleaner","HEPA filter removed",[38],{"name":39,"affiliation":5,"role":40},"Elena Austin, Sc.D.","PRINCIPAL_INVESTIGATOR",[42],{"name":43,"role":44,"phone":45,"phoneExt":46,"email":47},"Christine Loftus, PhD, MPH","CONTACT","206-753-9079",null,"cloftus@uw.edu",[49],{"facility":5,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Seattle","Washington","98195","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-122.33207,47.60621,{"lat":60,"lon":59},[63,67,71],{"name":64,"role":44,"phone":65,"phoneExt":46,"email":66},"Elena Austin, ScD","206-221-6301","elaustin@uw.edu",{"name":68,"role":44,"phone":69,"phoneExt":46,"email":70},"Maria Tchong-French","206-685-0465","mtchong@uw.edu",{"name":64,"role":40,"phone":46,"phoneExt":46,"email":46},{"type":40,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":46,"oldOrganization":46},"Elena Austin","Assistant Professor, Environmental & Occupational Health Sciences","100596589","the-airports-air-quality-and-asthma-aaa-study-100596589",false,"NCT07047430","The Airports, Air Quality, and Asthma (AAA) Study","Inclusion Criteria:\n\n* Child is 6-12 years old with a health care provider-diagnosed asthma.\n* Caregiver is comfortable in participating in all study activities in English (communicating with study staff by phone and completing online surveys).\n* Caregiver is familiar with the child's daily asthma health.\n* Residence within 10 miles of Seattle-Tacoma International Airport as determined by zip code\n* Child resides in caregiver's home at least five nights a week on a regular basis and has no plans to move in the next three months.\n\nExclusion Criteria:\n\n* Child has severe asthma at baseline. Severe asthma was defined in consultation with pediatric pulmonologists to be caregiver-reported asthma symptoms every day over the past 14 days and\u002For two or more inpatient hospitalizations for asthma in the past 12 months.\n* Households were excluded if there were multiple individuals within the same household with asthma eligible for the King County CHW Asthma Program or had severe asthma.","ALL","6 Years","12 Years",{"count":85,"type":86},60,"ESTIMATED","INTERVENTIONAL",[89],"NA","For children with asthma, exposure to indoor air pollution increases the risk of a serious asthma exacerbation, which can be life-threatening. Interventions aimed at improving indoor air quality, including use of a portable air cleaner with a high-efficiency particulate air (HEPA) filter, can reduce this risk, but the effectiveness, feasibility and acceptability of HEPA air cleaners varies by setting. In collaboration with a community health worker (CHW) delivered asthma education program, the investigators are conducting a randomized clinical trial to evaluate the effectiveness of HEPA air cleaners to improve indoor air quality and child asthma health in South King County of Washington state, a vulnerable community impacted by air pollution from airports and highway traffic. Key features of the Airports, Air Quality and Asthma (AAA) design include integration of CHWs into study procedures, including CHWs recruited from community-based organizations, into multiple aspects of the trial protocol. The investigators aim to recruit up to N=60 children with asthma randomized into intervention and control groups in a 1:1 ratio, conduct baseline assessments of indoor air quality and airway health, and collect repeated assessments of air quality and airway health during the three-month intervention period and after the trial concludes. Study findings will inform future approaches to integrate HEPA air cleaners into existing CHW asthma education programs in this and similar communities.",[92],"Pediatric Asthma",[94,95,35,96,97],"air quality","indoor air","pediatric asthma","community health workers","2025-06-27",{"date":100,"type":101},"2025-07-02","ACTUAL",{"date":103,"type":101},"2024-06-01",{"date":105,"type":86},"2027-06-01",{"name":5,"class":6},1]