[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100495940":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":77,"collaborators":26,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":26,"eligibilityCriteria":85,"healthyVolunteers":81,"sex":86,"minAge":87,"maxAge":26,"enrollmentInfo":88,"targetDuration":26,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":26,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Icahn School of Medicine at Mount Sinai","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Circadian Effective Lighting (CEL)","ACTIVE_COMPARATOR","The CEL will be performed in hospital sites over a 2-month period.",[13],"Device: Circadian Effective Lighting",{"label":15,"type":16,"description":17,"interventionNames":18},"Circadian Ineffective Lighting (CIL)","SHAM_COMPARATOR","The comparator lighting will be performed identical to Arm 1, at specified lower levels of lighting.",[19],"Device: Circadian Ineffective Lightning (CIL)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Circadian Effective Lighting","Participants will receive lighting with a spectrum of 300K, 500 lux to the eye level between 7:00am and 10:00am in the morning, and hospital lighting (\\\u003C100lux) during the afternoon between 10:00am and 6:00pm. In the evening this group of participants will receive lighting with a spectrum of 3000K, \\\u003C50lux at eye light level between 6:00PM and bedtime.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Circadian Ineffective Lightning (CIL)","Participants will receive lower lighting levels in the morning (lighting with A spectrum of 300k, \\\u003C50lux to the eye level between 7:00am and 10:00am) and the same lighting levels throughout the rest of the day.",[15],[32],{"name":33,"affiliation":5,"role":34},"Mariana Figueiro, PhD","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Barbara Plitnick, BSN","CONTACT","518 242-4603","Barbara.Plitnick@mountsinai.org",{"name":33,"role":38,"phone":42,"phoneExt":26,"email":43},"518-366-9306","Mariana.Figueiro@mountsinai.org",[45,65],{"facility":46,"status":47,"city":48,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Icahn Schoool of Medicine at Mount Sinai","RECRUITING","New York","10029","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-74.00597,40.71427,{"lat":56,"lon":55},[59,61,63],{"name":33,"role":38,"phone":42,"phoneExt":26,"email":60},"mariana.figueiro@mountsinai.org",{"name":37,"role":38,"phone":62,"phoneExt":26,"email":40},"518-242-4603",{"name":64,"role":34,"phone":26,"phoneExt":26,"email":26},"Mariana Figueiro",{"facility":66,"status":47,"city":48,"state":48,"zip":67,"country":50,"countryCode":51,"cosmosGeoPoint":68,"geoPoint":70,"contacts":71},"Memorial Sloan Kettering Cancer Center","10065",{"type":53,"coordinates":69},[55,56],{"lat":56,"lon":55},[72,75],{"name":73,"role":38,"phone":26,"phoneExt":26,"email":74},"Sergio Giralt, MD","giralts@mskcc.org",{"name":76,"role":34,"phone":26,"phoneExt":26,"email":26},"Sergio Giralt",{"type":34,"investigatorFullName":64,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Professor, Director of Light and Health Research Center at Mount Sinai","100495940","the-ambient-light-multiple-myeloma-study-100495940",false,"NCT05737732","The Ambient Light Multiple Myeloma Study","Systematic Light Exposure Effects on Circadian Rhythms Entrainment, Inflammation, Neutropenic Fever and Symptom Burden Among Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation","Inclusion Criteria:\n\n* Multiple Myeloma diagnosis\n* Scheduled to undergo their first Autologous Stem Cell Transplant procedure.\n* 21years or older\n* Able to provide informed consent.\n* English-language proficient\n\nExclusion Criteria:\n\n* Previous Autologous Stem Cell Transplant procedure\n* Pregnancy\n* Eye diseases which limit the ability of light to be processed\n* Secondary cancer diagnosis within the last 5 years\n* Severe sleep disorders\n* History of bipolar disorder or manic episodes\n* Severe psychological impairment\n* Previous use of light therapy\n* Active infection including COVID-19 infection","ALL","21 Years",{"count":89,"type":90},200,"ESTIMATED","INTERVENTIONAL",[93],"NA","The aim of this multi-site randomized control trial will be is to assess the impact Systematic lighting on circadian rhythm entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation. To achieve this aim, 200 multiple myeloma patients will receive one of two different light-treatments that are designed to promote circadian rhythm alignment. While receiving these light treatments, participants' sleep efficiency, urine melatonin levels, blood inflammatory cytokine levels and symptoms will be assessed over a 2-month period.",[96],"Multiple Myeloma","2026-06-10",{"date":99,"type":100},"2026-06-12","ACTUAL",{"date":102,"type":100},"2023-02-13",{"date":104,"type":90},"2027-06-30",{"name":5,"class":6},2]