[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558488":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":30,"responsibleParty":49,"collaborators":25,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":25,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":25,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":25,"overallStatus":32,"whyStopped":25,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Eye & ENT Hospital of Fudan University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Photosensitive hydrogel","EXPERIMENTAL","The photosensitive hydrogel is composed of tetra-armed poly(ethylene glycol) (4aPEGNB)and methacrylate-modified hyaluronic acid (HAMA).The hydrogel can be rapidly photocured under light induction at 395nm.",[13],"Device: Photosensitive hydrogel",{"label":15,"type":16,"description":17,"interventionNames":18},"Suture fixation","ACTIVE_COMPARATOR","The suture is fixed with 6-0 absorbable thread.",[19],"Device: 6-0 absorbable stitches",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","In the photosensitive hydrogel group, the anastomosis of the lacrimal cyst mucosal flap and the nasal mucoperiosteal flap was achieved by photosensitive hydrogel.",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"6-0 absorbable stitches","In the suture fixation group, the anastomosis of the lacrimal cyst mucosal flap and the nasal mucoperiosteal flap was achieved by two stitches using 6-0 absorbable wire.",[15],[31],{"facility":5,"status":32,"city":33,"state":25,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Shanghai","200031","China","CN",{"type":38,"coordinates":39},"Point",[40,41],121.45806,31.22222,{"lat":41,"lon":40},[44],{"name":45,"role":46,"phone":47,"phoneExt":25,"email":48},"Tong Lin, MD","CONTACT","13585764906","lintongwzmc@163.com",{"type":50,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100558488","the-application-of-photosensitive-hydrogel-in-intranasal-endoscopic-dacryocystorhinostomy-100558488",false,"NCT06551766","The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy","The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy for the Anastomosis of Lacrimal Cyst Flap and Nasal Mucoperiosteal Flap","Inclusion Criteria:\n\n1. Voluntarily participate in this clinical study and sign the informed consent;\n2. Gender is not limited, age 18-75 years old;\n3. The patient had symptoms and signs of chronic dacryocystitis, and the results of lacrimal passage irrigation suggested that the lower rush and return or upper rush and lower return, accompanied by mucous or purulent discharge reflux;\n4. Lacrimal duct angiography suggests nasolacrimal duct obstruction without lacrimal canaliculi and\u002For duct obstruction.\n\nExclusion Criteria:\n\n1. Age \\\u003C 18 or \\> 75 years old;\n2. Previous history of dacryocystonasal anastomosis;\n3. Abnormal coagulation function;\n4. Tumors of lacrimal passage, especially in patients with papilloma or malignant tumors;\n5. in the acute dacryocystitis attack stage;\n6. obvious scar constitution;\n7. Complicated with serious nasal diseases, such as severe allergic rhinitis, chronic rhinosinusitis and nasal polyps, acute suppurative rhinosinusitis, severe atrophic rhinitis, and severe deviation of nasal septum;\n8. Have serious heart, liver, kidney, lung and other basic diseases, can not tolerate general anesthesia;\n9. Distance from the hospital, postoperative review is not convenient;\n10. Participated in other clinical trials within the last 3 months;\n11. Any medical history that the investigator determines may interfere with the test results or increase the patient's risk.","ALL","18 Years","75 Years",{"count":62,"type":63},20,"ESTIMATED","INTERVENTIONAL",[66],"NA","To study the effect of Photosensitive hydrogel used for suture free anastomosis of lacrimal cyst and nasal mucoperiosteal flap in endoscopic nasal dacryocystostomy, and evaluate its adhesion to lacrimal cyst and nasal mucoperiosteal flap, promoting wound healing, forming a good anastomosis, preventing postoperative anastomosis and shortening operation time. Twenty patients with chronic dacryocystitis were randomly divided into photosensitive hydrogel group and suture group.Symptoms and nasal endoscopy were followed up 2, 6, and 12 weeks after surgery for both groups. And also adverse events were recorded at each follow-up.",[69],"Chronic Dacryocystitis","2024-08-09",{"date":72,"type":73},"2024-08-13","ACTUAL",{"date":75,"type":73},"2023-03-01",{"date":77,"type":63},"2024-12-31",{"name":5,"class":6},1]