[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100549321":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":39,"responsibleParty":57,"collaborators":61,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":18,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":18,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":42,"whyStopped":18,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"4℃ water drinking group","EXPERIMENTAL","Volunteers will drink 500ml 4℃ water within 10 minutes at 9a.m., 12p.m., 15p.m., 18p.m. everyday for 6 months.",[13],"Behavioral: Drinking cold water",{"label":15,"type":16,"description":17,"interventionNames":18},"37℃ water drinking group","NO_INTERVENTION","Volunteers will drink 500ml 37℃ water within 10 minutes at 9a.m., 12p.m., 15p.m., 18p.m. everyday for 6 months.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Drinking cold water","Volunteers in the intervention group will be asked to drink up 500 ml 4℃ water within 10 minutes four times per day throughout the study.",[9],[26],{"name":27,"affiliation":5,"role":28},"John R Speakman, PhD","STUDY_CHAIR",[30,35],{"name":27,"role":31,"phone":32,"phoneExt":33,"email":34},"CONTACT","15810868669","0755-86528487","j.speakman@abdn.ac.uk",{"name":36,"role":31,"phone":37,"phoneExt":33,"email":38},"Yinuo Wang, Master","15734075325","yi-nuo.wang@connect.polyu.hk",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences","RECRUITING","Shenzhen","Guangdong","518055","China","CN",{"type":49,"coordinates":50},"Point",[51,52],114.0683,22.54554,{"lat":52,"lon":51},[55,56],{"name":27,"role":31,"phone":32,"phoneExt":33,"email":34},{"name":36,"role":31,"phone":37,"phoneExt":33,"email":38},{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","John R. Speakman","Prof.",[62,64],{"name":63,"class":6},"Shenzhen University General Hospital",{"name":65,"class":6},"The Hong Kong Polytechnic University","100549321","the-association-between-core-temperature-and-health-100549321",false,"NCT06432491","The Association Between Core Temperature and Health","Study to Explore How Core Temperature Reduction Influence Health","Inclusion Criteria:\n\n* Aged between 50 and 65 years old (including 50 and 65)\n* No surgery in the past 6 months\n* Healthy (No metabolic diseases, cardiovascular diseases, lung diseases (COPD, asthma, et al.), endocrine diseases and gastrointestinal diseases)\n* Based in Shenzhen during the whole study period\n* No significant change on body weight in the past 3 months\n\nExclusion Criteria:\n\n* Those who need to take medication for a long term (including diet pills)\n* On a diet\n* Disabled\n* Females who are trying to get pregnant, pregnant, or breastfeeding\n* Presence of a metal implant in the body (e.g. pacemaker)\n* Those with claustrophobia\n* Those with blood phobia, pathological hypotension or hypertension\n* Those who are in other intervention studies",true,"ALL","50 Years","65 Years",{"count":78,"type":79},36,"ESTIMATED","INTERVENTIONAL",[82],"NA","The goal of this clinical trial is to learn if cold water drinking could promote body composition and further extend healthy lifespan in Chinese older adults. The main questions it aims to answer are:\n\n1. Does cold water drinking lower the body fat percentage?\n2. Will cold water drinking positively extend lifespan in a long-term Researchers will compare cold water intervention group to a control group (drinking 37℃ water instead) to see if cold water drinking works to promote health and slow down ageing process.\n\nParticipants will:\n\n1. Drink 4℃ or 37℃ water 4 times (9a.m., 12p.m., 15p.m., 18p.m.) every day for 6 months.\n2. Visit the institute and health checkup department for tests and checkup at baseline, the end of the 3rd month, and the end of 6th month.",[85,86,87],"Body Temperature Changes","Body Composition","Aging",[89,90,87],"Body temperature","Body composition","2026-01-19",{"date":93,"type":94},"2026-01-21","ACTUAL",{"date":96,"type":94},"2025-01-01",{"date":98,"type":79},"2026-12-31",{"name":5,"class":6},1]