[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100585254":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":29,"responsibleParty":44,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":50,"sex":54,"minAge":10,"maxAge":55,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":10,"overallStatus":65,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cardiac Surgery Patients",null,"Patients less than 18 years old who undergo cardiac surgical procedures on cardiopulmonary bypass.",[13],"Other: Collecting discarded blood samples",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Collecting discarded blood samples","Discarded blood samples will be collected from routine clinical labs collected before and after surgery.",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Koichi Yuki, MD","CONTACT","617-355-6115","koichi.yuki@childrens.harvard.edu",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Rachel Bernier, MPH","857-218-5438","rachel.bernier@childrens.harvard.edu",[30],{"facility":5,"status":10,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Boston","Massachusetts","02115","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-71.05977,42.35843,{"lat":40,"lon":39},[43],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Koichi Yuki","Principal Investigator, MD","100585254","the-association-between-tau--gfap-and-postoperative-neurological-impairment-in-patients-undergoing-cardiac-surgery-100585254",false,"NCT06899971","The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery","Inclusion Criteria:\n\n* less than 18 years old\n* undergoing cardiac surgery with cardiopulmonary bypass at Boston Children's Hospital\n\nExclusion Criteria:\n\n* undergoing an emergent procedure and do not have more than 1 hour ahead of time to review the consent\n* patient in a moribund condition American Society of Anesthesiology (ASA 5)\n* patient with a hematological and\u002For oncological disease\n* Jehovah witnesses\n* patient on preoperative mechanical ventilation","ALL","18 Years",{"count":57,"type":58},100,"ESTIMATED","OBSERVATIONAL","Patients born with heart defects often undergo surgical procedures on a heart lung machine. With improvements in medical and surgical management, their survival has significantly improved, but their brain insult has not been paid much attention. This study is to determine the relationship between specific proteins in the blood and brain injury in patients less than 18-year-old undergoing heart surgery.",[62,63,64],"Cardiac Surgery Requiring Cardiopulmonary Bypass","Brain Injury","Congenital Heart Defect","NOT_YET_RECRUITING","2026-03-16",{"date":68,"type":69},"2026-03-17","ACTUAL",{"date":71,"type":58},"2026-05-01",{"date":73,"type":58},"2027-12-31",{"name":5,"class":6},1]