[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605549":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":20,"responsibleParty":43,"collaborators":45,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":50,"sex":56,"minAge":7,"maxAge":57,"enrollmentInfo":58,"targetDuration":7,"studyType":61,"phases":7,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":72,"whyStopped":7,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Norfolk and Norwich University Hospitals NHS Foundation Trust","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Dr Isabel Iglesias-Platas","PRINCIPAL_INVESTIGATOR",[13,17],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},"CONTACT","01603288234","isabel.iglesias-platas@nnuh.nhs.uk",{"name":18,"role":14,"phone":7,"phoneExt":7,"email":19},"Professor Martin Warren","Martin.Warren@quadram.ac.uk",[21],{"facility":22,"status":7,"city":23,"state":7,"zip":7,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Norfolk and Norwich University Hospital NHS Foundation Trust","Norwich","United Kingdom","UK",{"type":27,"coordinates":28},"Point",[29,30],1.29834,52.62783,{"lat":30,"lon":29},[33,37,38,40],{"name":34,"role":14,"phone":35,"phoneExt":7,"email":36},"Julie Dawson","+441603 647882","Julie.dawson@nnuh.nhs.uk",{"name":10,"role":14,"phone":7,"phoneExt":7,"email":16},{"name":39,"role":11,"phone":7,"phoneExt":7,"email":7},"Dr isabel Iglesias-Platas",{"name":41,"role":42,"phone":7,"phoneExt":7,"email":7},"Professor Paul Clarke","SUB_INVESTIGATOR",{"type":44,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[46],{"name":47,"class":6},"Quadram Institute Bioscience","100605549","the-b-babies-study-an-observational-study-of-group-b-vitamins-in-preterm-infants-100605549",false,"NCT07163962","THE B-BABIES STUDY: An Observational Study of Group B Vitamins in Preterm Infants","Maternal, Milk and Baby Markers of Group B Vitamin Metabolism in (Very) Preterm Infants at the Time of Discharge Home","B-BABIES","Inclusion Criteria:\n\n* Gestational age at birth \\\u003C37 weeks.\n* Admission to one of the participating units.\n* Full enteral milk feeds established by suck\u002Fnasogastric tube\n\nExclusion Criteria:\n\n* Known or suspected chromosomal, genetic or metabolic abnormalities.\n* Major congenital malformations\n* Any intercurrent condition that precludes implementation of standard feeding protocols and requires specialized formulas or changes in standard vitamin supplementation.\n* Any intercurrent condition that will interfere with the interpretation of results (renal impairment and hypothyroidism can lead to elevated tHcy and MMA, for example).","ALL","28 Days",{"count":59,"type":60},40,"ESTIMATED","OBSERVATIONAL","Infancy may be associated with a risk of micronutrient depletion due to the high demands of rapid growth. This is particularly true when preterm birth occurs, as the period before term exhibits the highest rate of bodily growth across the lifespan. Folate and vitamin B12 are essential in development, and preterm infants may be particularly susceptible to deficiencies. This is the result of a combination of low stores and high requirements for fast growth and rapid red blood cell production in the context of multifactorial anaemia of prematurity. Micronutrient supply, including vitamin B12 and folate, is delivered through nutritional support, in the shape of parenteral nutrition, fortification of human milk of use of artificial formula. Most of this supplementation will be interrupted by the time the infant is getting ready for discharge home. The investigators previously reported high levels of serum folate in preterm infants at the time of discharge home and in early infancy, but there are no contemporary studies investigating the vitamin B12\u002Ffolate status in this population. The investigators aim to investigate the prevalence of vitamin B12 deficiency in preterm infants at the time of discharge home.",[64],"Vitamin B-12 Deficiency",[66,67,68,69,70,71],"Preterm infant","vitamin B12","Folate","Folic acid","Vitamin deficiency","Micronutrition","NOT_YET_RECRUITING","2025-09-05",{"date":75,"type":76},"2025-09-09","ACTUAL",{"date":78,"type":60},"2025-09-01",{"date":80,"type":60},"2026-09-30",{"name":5,"class":6},1]