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After the 36-month follow-up period, patients will receive follow-up usual care (i.e. CT-scans).\n\nThe scanning protocol of Boellaard et al (2015) is the basis of all center-specific protocols and therefore will be followed approximately (PET low dose CT 60 minutes post injection with scan trajectory from skull to (at least the) thighs followed by a CT scan).",[13,14],"Diagnostic Test: 18F FDG PET\u002FCT","Diagnostic Test: CT scan",{"label":16,"type":17,"description":18,"interventionNames":19},"Control group (care as usual)","ACTIVE_COMPARATOR","The control group (n = 345) consists of regular follow-up visits with physical check-ups and CT-scans at least every 6 months for the first 2 years and then at least yearly CT-scans until 3 years of follow-up. 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Patients may already be included during their curative intent treatment. Patients enter a screening period that runs until their randomization.\n\nInclusion Criteria:\n\nTo be eligible to participate in this study, a subject must meet all of the following criteria at the timing of randomization:\n\n* Cytological or histologically proven stage III non-small cell lung cancer before start of curative intent treatment\n* Treated with curative intent and started follow-up care\n* All adjuvant treatments are permitted as co-intervention during follow-up care\n* Age 18 years or older\n* ECOG Performance Status classification 0-2 at moment of inclusion\n* Written and signed informed consent by the patient or patient's representative (with the understanding that consent may be withdrawn by the patient or patient's representative at any time without consequences to future medical care)\n\nExclusion Criteria:\n\nA potential subject who meets any of the following criteria will be excluded from participation in this study:\n\n* Life expectancy shorter than 6 months at the end of curative intent treatment\n* Evidence of recurrence after end of curative intent treatment and before randomization (4 months follow-up)\n* Any condition that, in the opinion of the investigator, would interfere with evaluation of the intervention or interpretation of HRQOL or other study results.","ALL","18 Years",{"count":432,"type":433},690,"ESTIMATED","INTERVENTIONAL",[436],"NA","The primary objective of this study is to compare the 3-year overall survival of stage III NSCLC patients during follow-up surveillance with 18F-Fluorodeoxyglucose Positron Emission Tomography\u002F Computerized Tomography (18F FDG PET\u002FCT) versus follow-up with conventional CT surveillance.\n\nParticipants will receive usual care until 3 years of follow-up (control group) with additional whole-body 18F FDG PET\u002FCT scans during follow-up visits at 6 months, 12 months, 18 months, 24 months, and 36 months of follow-up in the intervention group.\n\nOther tasks include:\n\n* filling in quality of life (QOL) questionnaires at every time point;\n* participating in an interview evaluating the addition of the 18F FDG PET\u002FCT scans (optional);\n* collecting blood at the follow-up time points for our secondary endpoint (optional).\n\nResearchers will compare the usual care control group with the intervention group to see if the additional 18F FDG PET\u002FCT scans are (cost-)effective.",[439],"Stage III Non-small Cell Lung Cancer",[441,442],"18F FDG PET\u002FCT scans","Follow-up care","2025-02-04",{"date":445,"type":446},"2025-02-05","ACTUAL",{"date":448,"type":446},"2024-03-19",{"date":450,"type":433},"2029-06",{"name":5,"class":6},27]