[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100592269":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":42,"responsibleParty":55,"collaborators":26,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":26,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":26,"enrollmentInfo":66,"targetDuration":26,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":26,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"NYU Langone Health","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Total knee arthroplasty (TKA) + Cryoablation","EXPERIMENTAL","Patients will receive cryoablation during the two to three weeks prior to the TKA procedure.",[13,14],"Procedure: Total knee arthroplasty (TKA)","Device: Cryoablation",{"label":16,"type":17,"description":18,"interventionNames":19},"TKA Only","ACTIVE_COMPARATOR","Patients will NOT receive cryoablation prior to the TKA procedure.",[13],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Total knee arthroplasty (TKA)","Administered as part of patient standard of care.",[16,9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"DEVICE","Cryoablation","Cryoablation will be administered on the leg of the knee indicated for surgery.",[9],[33],{"name":34,"affiliation":5,"role":35},"Joshua Rozell, MD","PRINCIPAL_INVESTIGATOR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Daniel Waren","CONTACT","212-598-6245","Daniel.waren@nyulangone.org",[43],{"facility":5,"status":44,"city":45,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":26},"RECRUITING","New York","10016","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-74.00597,40.71427,{"lat":53,"lon":52},{"type":56,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100592269","the-benefits-of-cryoablation-in-patients-undergoing-total-knee-arthroplasty-100592269",false,"NCT06991231","The Benefits Of Cryoablation In Patients Undergoing Total Knee Arthroplasty","The Benefits Of Cryoablation In Patients Undergoing Total Knee Arthroplasty - A Randomized Prospective Clinical Trial","Inclusion Criteria:\n\n* Patients are candidates for elective primary total knee arthroplasty for a diagnosis of osteoarthritis or inflammatory arthritis.\n* Patients have been medically cleared and scheduled for surgery\n\nExclusion Criteria:\n\n* Patients with cold-related conditions (cryoglobulinemia, paroxysmal cold hemoglobinuria, cold urticaria, and Raynaud's disease)\n* Surgery for fracture, infection, or malignancy","ALL","18 Years",{"count":67,"type":68},215,"ESTIMATED","INTERVENTIONAL",[71],"NA","The purpose of this study is to evaluate the efficacy of cryoablation use on patient-reported outcomes (PROMs) and opioid consumption following total knee arthroplasty. This is a randomized study that will involve a 1:1 randomization to total knee arthroplasty +\u002F- cryoablation.",[74,75],"Post-Operative Pain","Total Knee Arthroplasty","2026-03-30",{"date":78,"type":79},"2026-04-03","ACTUAL",{"date":81,"type":79},"2025-06-13",{"date":83,"type":68},"2027-01-01",{"name":5,"class":6},1]