[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609894":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":29,"responsibleParty":47,"collaborators":49,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":10,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":72,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Wake Forest University Health Sciences","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants with ovarian or endometrial carcinoma with planned NACT.",null,"Participants over 55 years old with either ovarian\u002Fprimary peritoneal\u002Ffallopian tube carcinoma or endometrial carcinoma",[13],"Other: data collection",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"data collection","PROs, historical and longitudinal data collection and eFI calculation",[9],[20],{"name":21,"affiliation":5,"role":22},"Anna Kuan-Celarier, MD","PRINCIPAL_INVESTIGATOR",[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Sydney McEntire, RN","CONTACT","336-713-5879","sydney.mcentire@advocatehealth.org",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Wake Forest Baptist Comprehensive Cancer Center","RECRUITING","Winston-Salem","North Carolina","27157","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-80.24422,36.09986,{"lat":42,"lon":41},[45,46],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},{"name":21,"role":22,"phone":10,"phoneExt":10,"email":10},{"type":48,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[50],{"name":51,"class":6},"Atrium Health Wake Forest Baptist","100609894","the-better-harder-faster-stronger-study-100609894",false,"NCT07220512","The Better, Harder, Faster, Stronger Study","The BHFS Study (Better, Harder, Faster, Stronger): Does Neoadjuvant Chemotherapy Improve Fitness for Surgery?","Inclusion Criteria:\n\n* Ability to understand and willingness to sign an IRB-approved informed consent.\n* Age \\> 55 years at the time of enrollment.\n* Newly diagnosed suspected ovarian\u002Fprimary peritoneal\u002Ffallopian tube carcinoma of any histological subtype, FIGO Stage II-IV, per enrolling investigator, or newly diagnosed suspected endometrial carcinoma of any histologic subtype, FIGO Stage II-IV, per enrolling investigator.\n* Planned for 3 or 4 cycles of NACT, with interval cytoreductive surgery planned thereafter.\n* Ability to read, understand, and write the English language.\n* As determined by the enrolling investigator, ability of the participant to understand and comply with study procedures for the entire length of the study.\n\nExclusion Criteria:\n\n* History of brain metastases.\n* History of poorly controlled psychiatric conditions, defined as hospitalization within the prior 3 months for psychiatric disorders, traumatic brain injury, cerebrovascular event, or dementia, per the enrolling investigator.\n* Use of anti-amyloid agents, cholinesterase inhibitors, or glutamate regulators at the time of enrollment.\n* Vision impairment that would impede completion of study assessments, per enrolling investigator.","FEMALE","55 Years",{"count":62,"type":63},35,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to evaluate changes in the electronic Frailty Index (eFI) score following 3-4 cycles of neoadjuvant chemotherapy (NACT) in participants with advanced ovarian and endometrial cancer.",[67,68,69,70,71],"Frailty at Older Adults","Ovarian Cancer","Endometrial Cancer","Cognitive Dysfunction","Neoadjuvant Chemotherapy",[73,74,75,76,77],"Frailty","ovarian cancer","endometrial cancer","cognitive dysfunction","neoadjuvant chemotherapy","2025-10-22",{"date":80,"type":81},"2025-10-24","ACTUAL",{"date":83,"type":81},"2025-07-28",{"date":85,"type":63},"2027-05",{"name":5,"class":6},1]