[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100542178":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":10,"locations":20,"responsibleParty":45,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":23,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Dongzhimen Hospital, Beijing","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"POI Group",null,"The patients with premature ovarian insufficiency",[13],"Diagnostic Test: Testing the serum levels of bone metabolic markers",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Testing the serum levels of bone metabolic markers","Testing serum levels of TRACP-5b and BALP, BMD values of lumbar spine L1-L4, left and right hip, left and right femoral neck et.al.",[9],[21],{"facility":22,"status":23,"city":24,"state":10,"zip":10,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"Dongzhimen Hospital, Beijing University of Chinese Medicine","RECRUITING","Beijing","China","CN",{"type":28,"coordinates":29},"Point",[30,31],116.39723,39.9075,{"lat":31,"lon":30},[34,39,42],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Xueting Han","CONTACT","+861084012709","dzmyyec@126.com",{"name":40,"role":41,"phone":10,"phoneExt":10,"email":10},"Yun Shi, phD","PRINCIPAL_INVESTIGATOR",{"name":43,"role":44,"phone":10,"phoneExt":10,"email":10},"Ke Xu, Master","SUB_INVESTIGATOR",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Shi Yun","Sponsor-Investigator","100542178","the-bone-metabolism-characteristics-of-premature-ovarian-insufficiency-100542178",false,"NCT06339489","The Bone Metabolism Characteristics of Premature Ovarian Insufficiency","Explore the Bone Metabolism Characteristics of Premature Ovarian Insufficiency","POI","Inclusion Criteria:\n\nPatients diagnosed by Western medicine with premature ovarian insufficiency. 18 ≤ patients' age ≤ 39 years;. Patients who voluntarily participate in this study, sign an informed consent form.\n\nExclusion Criteria:\n\nPatients with congenital gonadal dysplasia or a family history similar to \"early menopause\".\n\nPOI patients with acquired organic lesions or ovarian surgery. Patients who have taken Western or herbal medicine artificial cycle therapy or other endocrine therapy in the past three months.\n\nPatients with serious primary diseases and mental disorders such as cardiovascular and cerebrovascular, liver, kidney and hematopoietic system.\n\nPatients who are breastfeeding or pregnant.","FEMALE","18 Years","39 Years",{"count":61,"type":62},60,"ESTIMATED","OBSERVATIONAL","Explore the bone metabolism characteristics of premature ovarian insufficiency.",[66,67,68],"Premature Ovarian Insufficiency","Bone Diseases, Metabolic","Bone Mineral Density","2024-06-21",{"date":71,"type":72},"2024-06-25","ACTUAL",{"date":74,"type":72},"2024-04-01",{"date":76,"type":62},"2025-02-01",{"name":47,"class":6},1]