[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100513411":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":18,"locations":28,"responsibleParty":52,"collaborators":7,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":7,"enrollmentInfo":65,"targetDuration":7,"studyType":68,"phases":7,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":31,"whyStopped":7,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Shanghai Zhongshan Hospital","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Sample of Blood","All participants will receive M-protein screening by serum electrophoresis. Individuals with detected M-protein will undergo further diagnostic tests to determine their accurate diagnosis. Patients with monoclonal gammopathy of undetermined significance (MGUS) would be carefully assessed and followed up.",[14],{"name":15,"affiliation":16,"role":17},"Peng Liu, PhD, MD","Fudan University","PRINCIPAL_INVESTIGATOR",[19,24],{"name":15,"role":20,"phone":21,"phoneExt":22,"email":23},"CONTACT","+8621-64041990","2925","liu.peng@zs-hospital.sh.cn",{"name":25,"role":20,"phone":21,"phoneExt":26,"email":27},"Jing Li, MD","2025","li.jing6@zs-hospital.sh.cn",[29],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Zhongshan Hospital，Fudan University","RECRUITING","Shanghai","Shanghai Municipality","200032","China","CN",{"type":38,"coordinates":39},"Point",[40,41],121.45806,31.22222,{"lat":41,"lon":40},[44,47,49,50],{"name":45,"role":20,"phone":46,"phoneExt":22,"email":23},"Peng Liu, Ph.D","+862164041990",{"name":48,"role":20,"phone":46,"phoneExt":26,"email":27},"Jing Li, M.D.",{"name":45,"role":17,"phone":7,"phoneExt":7,"email":7},{"name":48,"role":51,"phone":7,"phoneExt":7,"email":7},"SUB_INVESTIGATOR",{"type":17,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Peng Liu","Head of Department of Hematology","100513411","the-china-m-protein-screening-project-in-first-degree-relatives-of-myeloma-patient---the-chaperone-study-100513411",false,"NCT05965115","The China M-protein Screening Project in First-degree Relatives of Myeloma Patient - The CHAPERONE Study","The China Monoclonal Gammopathy Screening Project in First-degree Relatives of Patients With Multiple Myeloma (CHAPERONE) --A Multicenter Observational Study","CHAPERONE","Inclusion Criteria:\n\n1. Male or female over the age of 18;\n2. First-degree relatives (including parents, children, and biological siblings) have multiple myeloma diagnosed by the International Myeloma Working Group (IMWG) Myeloma Diagnostic Criteria;\n3. Understand the purpose and procedure of this trial and voluntarily participate in this screening study;\n4. Participants should be willing and able to follow the study follow-up plan and other protocol requirements.\n\nExclusion Criteria:\n\nPatients with a known diagnosis of plasma cell diseases, such as MGUS, smoldering myeloma (SMM), or multiple myeloma","ALL","18 Years",{"count":66,"type":67},10000,"ESTIMATED","OBSERVATIONAL","The goal of the China Monoclonal Gammopathy Screening Project in First-degree Relatives of Patients With Multiple Myeloma (CHAPERONE) study is to assess the clinical significance of screening for monoclonal gammopathy (M-protein) in first-degree relatives of patients with multiple myeloma in China population, and establish a prospective cohort of individuals with monoclonal gammopathy of undetermined significance (MGUS), a precursor conditions to multiple myeloma. We will study these patients as a means to identify risk factors for progression to symptomatic multiple myeloma.",[71,72],"Multiple Myeloma","Monoclonal Gammopathy of Undetermined Significance",[72,71,74],"Early Tumor Screening","2023-07-31",{"date":77,"type":78},"2023-08-01","ACTUAL",{"date":80,"type":67},"2023-07",{"date":82,"type":67},"2035-08",{"name":5,"class":6},1]