[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599715":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":17,"centralContacts":17,"locations":17,"responsibleParty":30,"collaborators":17,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":38,"acronym":39,"eligibilityCriteria":40,"healthyVolunteers":36,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":17,"studyType":47,"phases":48,"briefSummary":50,"conditions":51,"keywords":17,"overallStatus":54,"whyStopped":17,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":17},{"fullName":5,"class":6},"Beijing Tsinghua Chang Gung Hospital","OTHER",[8,13,18],{"label":9,"type":10,"description":9,"interventionNames":11},"Bone-patellar tendon-bone allograft transplantation","EXPERIMENTAL",[12],"Procedure: bone-patellar tendon-bone or meniscus allograft transplantation techniques",{"label":14,"type":15,"description":16,"interventionNames":17},"Control group","NO_INTERVENTION","non-surgical or conservative treatment group",null,{"label":19,"type":10,"description":19,"interventionNames":20},"Quasi-anatomical meniscus allograft transplantation",[21],"Procedure: Quasi-anatomical meniscus allograft transplantation",[23,28],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":17},"PROCEDURE","bone-patellar tendon-bone or meniscus allograft transplantation techniques","This clinical study follows an interventional design, focusing on the evaluation of bone-patellar tendon-bone and quasi-anatomical meniscus allograft transplantation techniques。",[9],{"type":24,"name":19,"description":19,"armGroupLabels":29,"otherNames":17},[19],{"type":31,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","YujiakuoTHU","Principal Investigator","100599715","the-clinical-study-of-bone-patellar-tendon-bone-and-quasi-anatomical-meniscus-allograft-transplantation-technique-100599715",false,"NCT07088094","The Clinical Study of Bone-patellar Tendon-bone and Quasi-anatomical Meniscus Allograft Transplantation Technique","BPTB，Meniscus","Inclusion Criteria:\n\n* Aged 18-50 years\n* Clinical diagnosis of symptomatic meniscal deficiency and anterior cruciate ligament injury (complete rupture or severe damage)\n* Failure of conservative treatment (e.g., physical therapy, analgesia) for ≥6 months\n* Stable knee joint (no ligamentous instability confirmed via clinical exam and MRI)\n* Willingness to comply with postoperative rehabilitation and follow-up evaluations\n\nExclusion Criteria:\n\n* Severe tibiofemoral osteoarthritis (Kellgren-Lawrence grade ≥3)\n* History of prior knee infection or septic arthritis\n* Inflammatory arthritis (e.g., rheumatoid arthritis, gout)\n* BMI ≥35 kg\u002Fm²\n* Pregnancy or planning pregnancy during the study period\n* Concurrent full-thickness chondral defects (Outerbridge grade III-IV) in the affected compartment\n* Inability to undergo MRI (e.g., claustrophobia, metallic implants)","ALL","18 Years","60 Years",{"count":45,"type":46},200,"ESTIMATED","INTERVENTIONAL",[49],"NA","This clinical study investigates the outcomes of bone-patellar tendon-bone and quasi-anatomical meniscus allograft transplantation techniques in patients requiring joint reconstruction. The study aims to assess the safety, efficacy, and functional improvements following these transplant procedures, utilizing donor tissues to restore joint function and alleviate pain in individuals with severe knee damage. Participants will undergo the transplantation procedure and be monitored for post-operative recovery, complications, and long-term outcomes, including joint stability and mobility. The study seeks to provide valuable insights into the effectiveness of these advanced surgical techniques for knee joint repair.",[52,53],"Meniscal Tears","ACL - Anterior Cruciate Ligament Rupture","NOT_YET_RECRUITING","2025-07-17",{"date":57,"type":58},"2025-07-28","ACTUAL",{"date":60,"type":46},"2025-08-01",{"date":62,"type":46},"2028-05-31",{"name":5,"class":6}]