[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569974":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":18,"centralContacts":23,"locations":29,"responsibleParty":47,"collaborators":7,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":59,"maxAge":7,"enrollmentInfo":60,"targetDuration":63,"studyType":64,"phases":7,"briefSummary":65,"conditions":66,"keywords":7,"overallStatus":31,"whyStopped":7,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Vanderbilt-Ingram Cancer Center","OTHER",null,[9,12,15],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Blood collection","Blood will be taken from participants already undergoing blood collection",{"type":6,"name":13,"description":14,"armGroupLabels":7,"otherNames":7},"Saliva collection","Undergo saliva collection",{"type":6,"name":16,"description":17,"armGroupLabels":7,"otherNames":7},"Bone marrow collection","Bone marrow will be taken from participants already undergoing bone marrow collection",[19],{"name":20,"affiliation":21,"role":22},"Alexander Bick, MD, PhD","Vanderbilt University\u002FIngram Cancer Center","PRINCIPAL_INVESTIGATOR",[24],{"name":25,"role":26,"phone":27,"phoneExt":7,"email":28},"Vanderbilt-Ingram Services for Timely Access","CONTACT","800-811-8480","cip@vumc.org",[30],{"facility":21,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Nashville","Tennessee","37203","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-86.78444,36.16589,{"lat":41,"lon":40},[44,46],{"name":45,"role":26,"phone":27,"phoneExt":7,"email":28},"Vanderbilt-Ingram Service Services for Timely Access",{"name":20,"role":22,"phone":7,"phoneExt":7,"email":7},{"type":22,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Alexander Bick","Assistant Professor Medicine, Division of Genetic Medicine","100569974","the-clonal-hematopoiesis--inflammation-in-vasculature-registry-and-biorepository-100569974",false,"NCT06701214","The Clonal Hematopoiesis & Inflammation in Vasculature Registry and Biorepository","Discovering Outcomes in Clonal Hematopoiesis: The Clonal Hematopoiesis and Inflammation in VasculaturE (CHIVE) Registry and Biorepository","CHIVE","Inclusion Criteria:\n\n* Patient greater than or equal to 18 years old at time of consent\n* Able to provide informed consent\n* Idiopathic cytopenia (ICUS) or idiopathic cytoses (elevated blood counts without disease or explanation); clonal cytopenia of undetermined significance (CCUS), clonal hematopoiesis of indeterminate potential (CHIP) or individuals at higher risk for clonal hematopoiesis (ex. patients with known diagnosis of solid tumors or cardiovascular disease)\n\nExclusion Criteria:\n\n* Unable to provide consent\n* Diagnosis of active hematologic malignancy. For example, a diagnosis of CMML, AML, MDS, MPN; History of hematologic malignancy is NOT exclusionary if in complete remission (e.g. previous myeloma or lymphoma)","ALL","18 Years",{"count":61,"type":62},800,"ESTIMATED","10 Years","OBSERVATIONAL","This study will investigate the association between clonal hematopoiesis and other conditions. Clonal hematopoiesis (CH) refers to the mutations in a person's stem cells which commonly affect people as they get older. These mutations have notably been linked to increased risk of certain cancers as well as increased risk of heart disease.",[67],"Clonal Hematopoiesis","2024-11-20",{"date":70,"type":71},"2024-11-22","ACTUAL",{"date":73,"type":71},"2020-10-28",{"date":75,"type":62},"2031-11-30",{"name":5,"class":6},1]