[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643922":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":42,"locations":48,"responsibleParty":65,"collaborators":28,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":28,"eligibilityCriteria":72,"healthyVolunteers":69,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":28,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":28,"overallStatus":51,"whyStopped":28,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Yeditepe University","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental - Combined Treatment Group","EXPERIMENTAL","Mulligan Mobilization + Pain Neuroscience Education + Core Stabilization Exercises",[13,14,15],"Behavioral: Pain Neuroscience Education (PNE)","Procedure: Mulligan Mobilization With Movement (MWM)","Behavioral: Core Stabilization Exercises",{"label":17,"type":18,"description":19,"interventionNames":20},"Active Comparator - Conventional Physical Therapy Group","ACTIVE_COMPARATOR","Conventional Physical Therapy (TENS + hot-pack + ROM Exercises + Stretching Exercises)",[21],"Other: Conventional Physical Therapy",[23,29,34,38],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"BEHAVIORAL","Pain Neuroscience Education (PNE)","Participants will receive Pain Neuroscience Education focused on the biopsychosocial nature of pain, central sensitization, the distinction between pain and tissue damage, and strategies to reduce fear of movement. The initial educational session will last approximately 15-20 minutes, followed by 5-10 minute reinforcement sessions throughout the intervention period. Education will be delivered through verbal explanations and interactive discussion.",[9],null,{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":28},"PROCEDURE","Mulligan Mobilization With Movement (MWM)","Participants will receive Mulligan Mobilization with Movement techniques applied to the glenohumeral joint, including posterolateral glide with active abduction, inferior glide with shoulder flexion, and posterior glide with internal rotation. Mobilizations will be performed within a pain-free range of motion. Each technique will be administered in 3 sets of 10 repetitions with 30 seconds of rest between sets. Treatment will be provided three times per week for six weeks",[9],{"type":24,"name":35,"description":36,"armGroupLabels":37,"otherNames":28},"Core Stabilization Exercises","Participants will perform Dynamic Neuromuscular Stabilization (DNS)-based core stabilization exercises. The program will include diaphragmatic breathing, supine 90\u002F90 positioning, abdominal bracing, and progression to dead bug, bird-dog, and modified plank exercises as tolerated. Exercises will be performed in 2-3 sets of 8-12 repetitions with 10-20 second isometric holds. Progression will occur from stable to unstable surfaces and from static to dynamic activities",[9],{"type":6,"name":39,"description":40,"armGroupLabels":41,"otherNames":28},"Conventional Physical Therapy","Participants in the control group will receive conventional physical therapy consisting of transcutaneous electrical nerve stimulation (TENS) applied at a sensory level for 20 minutes, hot-pack application for 20 minutes, passive shoulder joint mobilization exercises, pendulum exercises, and wand exercises. Treatment sessions will be conducted three times per week for six weeks.",[17],[43],{"name":44,"role":45,"phone":46,"phoneExt":28,"email":47},"Dilay Döner","CONTACT","+90 0535 019 58 83","dilay.doner@std.yeditepe.edu.tr",[49],{"facility":50,"status":51,"city":52,"state":28,"zip":28,"country":53,"countryCode":28,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Life Med Tıp Merkezi","RECRUITING","Istanbul","Turkey (Türkiye)",{"type":55,"coordinates":56},"Point",[57,58],28.94966,41.01384,{"lat":58,"lon":57},[61],{"name":62,"role":45,"phone":63,"phoneExt":28,"email":64},"Murat Gökhan Döner","+90 532 342 98 15","fztgokhandoner@gmail.com",{"type":66,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR","100643922","the-combined-effect-of-mulligan-mobilization-pain-neuroscience-based-training-and-core-stabilization-exercises-in-frozen-shoulder-patients-100643922",false,"NCT07667556","The Combined Effect of Mulligan Mobilization, Pain Neuroscience-Based Training, and Core Stabilization Exercises in Frozen Shoulder Patients","Inclusion Criteria:\n\n* Adults aged 18 to 65 years\n* Diagnosis of adhesive capsulitis confirmed by an orthopedic surgeon or a physical medicine and rehabilitation physician\n* Presence of shoulder pain and limitation of shoulder range of motion\n* Ability to communicate verbally\n* Ability to understand study procedures and educational content\n* Willingness to participate and provide written informed consent\n* Mini-Mental State Examination (MMSE) score of 24 or higher\n* Ability to attend treatment and assessment sessions regularly\n\nExclusion Criteria:\n\n* MMSE score below 24\n* Severe cognitive impairment\n* Severe psychiatric disorders\n* Active infectious disease\n* Active malignancy\n* Uncontrolled cardiovascular disease\n* Presence of a cardiac pacemaker\n* Contraindications to transcutaneous electrical nerve stimulation (TENS)\n* Neurological disorders that may affect participation or outcomes\n* Systemic diseases that may interfere with the safe implementation of the intervention\n* Inability to comply with the study protocol or attend scheduled sessions","ALL","18 Years","65 Years",{"count":77,"type":78},36,"ESTIMATED","INTERVENTIONAL",[81],"NA","The purpose of this randomized controlled study is to investigate the effects of a combined rehabilitation program consisting of Mulligan Mobilization with Movement (MWM), Pain Neuroscience Education (PNE), and core stabilization exercises in individuals with adhesive capsulitis (frozen shoulder).\n\nThe main questions this study aims to answer are:\n\nDoes the combination of Mulligan mobilization, Pain Neuroscience Education, and core stabilization exercises reduce pain in individuals with adhesive capsulitis? Does this combined intervention improve shoulder range of motion, shoulder function, quality of life, scapular dyskinesis, and pain catastrophizing compared with conventional physical therapy?\n\nParticipants diagnosed with adhesive capsulitis will be randomly assigned to one of two groups. The intervention group will receive Mulligan mobilization, Pain Neuroscience Education, and core stabilization exercises, while the control group will receive conventional physical therapy, including TENS, hot-pack application, passive joint mobilization, and stretching exercises. Both groups will participate in treatment sessions three times per week for six weeks. Outcome measures will be assessed at baseline and after completion of the 6-week intervention period.",[84],"Frozen Shoulder","2026-06-19",{"date":87,"type":88},"2026-06-25","ACTUAL",{"date":90,"type":88},"2026-04-21",{"date":92,"type":78},"2026-06",{"name":5,"class":6},1]