[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594112":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":27,"responsibleParty":74,"collaborators":76,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":87,"acronym":10,"eligibilityCriteria":88,"healthyVolunteers":85,"sex":89,"minAge":90,"maxAge":10,"enrollmentInfo":91,"targetDuration":10,"studyType":94,"phases":10,"briefSummary":95,"conditions":96,"keywords":104,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"Institute of Health Information and Statistics of the Czech Republic","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"A woman over 18 years old in the first trimester of pregnancy (11th-13th gestational week)",null,"A participant in the project must have signed the Consent to Participate in the Project and the Consent to the Processing of Personal Data.",[13],{"name":14,"affiliation":15,"role":16},"Marek Ľubušký, prof.","THE FETAL MEDICINE CENTRE, Department of Obstetrics and Gynecology, Palacky University Olomouc, Faculty of Medicine and Dentistry, University Hospital Olomouc","STUDY_DIRECTOR",[18,23],{"name":19,"role":20,"phone":21,"phoneExt":10,"email":22},"Petra Brlica Heideová, Msc.","CONTACT","+420 770 171 533","Petra.BrlicaHeideova@uzis.cz",{"name":24,"role":20,"phone":25,"phoneExt":10,"email":26},"Lucie Mandelová, PhD","+420 770 190 828","lucie.mandelova@uzis.cz",[28,46,60],{"facility":29,"status":30,"city":31,"state":32,"zip":10,"country":32,"countryCode":10,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Regional Health Corpotarion - Most Hospital","RECRUITING","Most","Czechia",{"type":34,"coordinates":35},"Point",[36,37],13.63617,50.50301,{"lat":37,"lon":36},[40,44],{"name":41,"role":20,"phone":42,"phoneExt":10,"email":43},"Marian Kacerovský, Prof.","+420777657991","KacerovskyM@lfhk.cuni.cz",{"name":41,"role":45,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"facility":47,"status":30,"city":48,"state":32,"zip":10,"country":32,"countryCode":10,"cosmosGeoPoint":49,"geoPoint":53,"contacts":54},"University Hospital Olomouc","Olomouc",{"type":34,"coordinates":50},[51,52],17.25175,49.59552,{"lat":52,"lon":51},[55,59],{"name":56,"role":20,"phone":57,"phoneExt":10,"email":58},"Michaela Maděrková Tozzi, MD., Ph.D.","+420724991367","cfm@fnol.cz",{"name":56,"role":45,"phone":10,"phoneExt":10,"email":10},{"facility":61,"status":30,"city":62,"state":32,"zip":10,"country":32,"countryCode":10,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Institute for the Care of Mother and Child","Prague",{"type":34,"coordinates":64},[65,66],14.42076,50.08804,{"lat":66,"lon":65},[69,73],{"name":70,"role":20,"phone":71,"phoneExt":10,"email":72},"Ladislav Krofta, Prof.","+420296511837","ladislav.krofta@upmd.eu",{"name":70,"role":45,"phone":10,"phoneExt":10,"email":10},{"type":75,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[77,79,81],{"name":47,"class":78},"OTHER",{"name":80,"class":78},"Institute for the Care of Mother and Child, Prague, Czech Republic",{"name":82,"class":78},"Krajská zdravotní, a.s. - Nemocnice Most, o.z.","100594112","the-combined-first-trimester-screening-100594112",false,"NCT07015203","The Combined First Trimester Screening","Inclusion Criteria:\n\n* A woman over 18 years old in the first trimester of pregnancy (11th-13th gestational week)\n* Signed the Consent to Participate in the Project and GDPR.\n\nExclusion Criteria:\n\n* Unsigned the Consent to Participate in the Project and the Consent to the Processing of Personal Data.","FEMALE","18 Years",{"count":92,"type":93},2000,"ESTIMATED","OBSERVATIONAL","The project is a national, prospective, multicenter pilot project. The project is focus on setting up the combined first trimester screening in the Czech Republic.\n\nThe combined first trimester screening is aimed at predicting and detecting the most serious obstetric complications, such as the great obstetrical syndromes (preeclampsia, fetal growth restriction, preterm labor and intrauterine fetal demise \"IUFD\") and structural congenital defects (morphological and chromosomal).\n\nThe primary objective of the project is to create a unified methodology for performing and evaluating the combined first trimester screening in connection with the National Health Information System (hereinafter referred to as \"NHIS\"), which will enable recording, providing analysis and linking recorded clinical parameters with data in the NHIS. The pilot project will also provide data for modeling appropriate mechanisms for reimbursement from public health insurance.",[97,98,99,100,101,102,103],"Preeclampsia (PE)","Fetal Growth Restriction","Congenital Abnormalities","Preterm Labor","Intrauterine Fetal Demise","Genetics Syndrome","Pregnancy Overdue - Week 41+6",[105,106,107,108,109,110,111,112,113],"preeclampsia","prediction","prevention","maternal risk factors","Mean Arterial Pressure","Uterine artery Pulsatility Index","Placental Growth Factor","acetylsalicylic acid","Czech Republic","2026-04-16",{"date":116,"type":117},"2026-04-17","ACTUAL",{"date":119,"type":117},"2025-06-15",{"date":121,"type":93},"2027-04-30",{"name":5,"class":6},3]