[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572790":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":26,"responsibleParty":41,"collaborators":26,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":26,"eligibilityCriteria":50,"healthyVolunteers":47,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":26,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":26,"overallStatus":63,"whyStopped":26,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":26},{"fullName":5,"class":6},"Army Medical University, China","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Single Catheter Adrenal Vein Sampling","EXPERIMENTAL","Patients in the Intervention group will utilize a multifunctional catheter for bilateral adrenal vein sampling.",[13],"Procedure: Single catheter adrenal vein sampling",{"label":15,"type":16,"description":17,"interventionNames":18},"Double Catheter Adrenal Vein Sampling","ACTIVE_COMPARATOR","Patients in this group will utilize two catheters for bilateral adrenal vein sampling.",[19],"Procedure: Double catheters adrenal vein sampling",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Single catheter adrenal vein sampling","The clinical invasive procedure involves inserting a single catheter into the right and left adrenal veins to collect blood samples from both adrenal veins.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Double catheters adrenal vein sampling","The clinical invasive procedure involves inserting double catheters into the right and left adrenal veins to collect blood samples from both adrenal veins.",[15],[32],{"name":33,"affiliation":5,"role":34},"Li Li, MD","STUDY_DIRECTOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Li Li,MD","CONTACT","13372683559","doublepear@tmmu.edu.cn",{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Li Li","Deputy Director of the department of Hypertension & Endocrinology, Daping Hospital","100572790","the-comparison-of-single-catheter-and-double-catheter-adrenal-vein-sampling-methods-based-on-the-upper-limb-approach-100572790",false,"NCT06737848","The Comparison of Single Catheter and Double Catheter Adrenal Vein Sampling Methods Based on the Upper Limb Approach","Inclusion Criteria:\n\n* Patients aged 18-70 years with hypertension.\n* Initial screening shows a standing aldosterone\u002Frenin ratio (ARR) \\> 3.7, a baseline aldosterone level \\> 10 ng\u002Fdl, aldosterone level \\> 6 ng\u002Fdl after a saline load test, or aldosterone decrease of less than 30% after a captopril suppression test, consistent with a diagnosis of primary aldosteronism.\n* Voluntary participation in the trial, with signed informed consent.\n\nExclusion Criteria:\n\n* Patients with an allergy to iodinated contrast agents.\n* Patients who are pregnant, breastfeeding, or planning to become pregnant.\n* Patients with severe comorbidities, such as renal failure, liver cirrhosis, metastatic tumors, or those who have had an acute stroke or acute myocardial infarction, as well as patients with a history of surgery within the past month.\n* Patients suspected of having adrenal cortical carcinoma.","ALL","18 Years","70 Years",{"count":55,"type":56},70,"ESTIMATED","INTERVENTIONAL",[59],"NA","Primary Aldosteronism (PA) is a clinical syndrome characterized by the autonomous overproduction of aldosterone by the adrenal cortex's zona glomerulosa, leading to hypertension, elevated aldosterone levels, and suppressed renin activity as the primary manifestations. Studies have shown that the prevalence of PA in an unselected hypertensive population ranges from 5% to 11% , while the prevalence in patients with resistant hypertension is approximately 20% . PA is one of the most common causes of secondary hypertension , and its prevalence increases with rising blood pressure levels. Due to the adverse effects of PA on the heart, arterial walls, and kidneys, it contributes to the occurrence of cardiovascular events, with atrial fibrillation being the most common . In summary, PA is characterized by rapid onset, significant symptoms, obscurity, and severe complications, making early diagnosis and targeted treatment essential for prevention.\n\nThis study aims to explore a quasi-selected prospective randomized controlled method to compare the clinical efficacy differences between single-catheter and dual-catheter adrenal sampling via the right upper limb approach. The study seeks to clarify the effectiveness and safety of single-catheter sampling from the upper limb, providing a more efficient and cost-effective solution for the subtype diagnosis of patients with Primary Aldosteronism (PA).",[62],"Primary Aldosteronism","NOT_YET_RECRUITING","2024-12-12",{"date":66,"type":67},"2024-12-17","ACTUAL",{"date":69,"type":56},"2024-12-30",{"date":71,"type":56},"2025-07-31",{"name":5,"class":6}]