[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548261":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":26,"responsibleParty":44,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":55,"maxAge":10,"enrollmentInfo":56,"targetDuration":59,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":72,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Zhujiang Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients with acute ischemic stroke due to large or medium vessel occlusion",null,"Patients with acute ischemic stroke due to large or medium vessel occlusion meeting inclusion criteria, must accept mechanical thrombectomy and have CT images which can get the IAC Agatston score.",[13],{"name":14,"affiliation":5,"role":15},"Duan Chuanzhi, MD","PRINCIPAL_INVESTIGATOR",[17,22],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},"Feng Xin, MD","CONTACT","+8613681134001","13681134001@163.com",{"name":23,"role":19,"phone":24,"phoneExt":10,"email":25},"Wen Zhuohua, MD","+8615622311746","810107327@qq.com",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Zhujiang Hospital, Southern Medical University","RECRUITING","Guangzhou","Guangdong","528400","China","CN",{"type":36,"coordinates":37},"Point",[38,39],113.25,23.11667,{"lat":39,"lon":38},[42,43],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},{"name":23,"role":19,"phone":24,"phoneExt":10,"email":25},{"type":45,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100548261","the-correlation-of-intracranial-artery-calcification-and-outcomes-of-mechanical-thrombectomy-100548261",false,"NCT06418698","The Correlation of Intracranial Artery Calcification and Outcomes of Mechanical Thrombectomy","The Prediction of Intracranial Artery Calcification on Adverse Outcomes of Large Vessel Occlusive, Acute Ischemic Stroke Patients After Mechanical Thrombectomy: A Prospective Cohort, Observational Study","CAIS-MT","Inclusion Criteria:\n\n* Male or non-pregnant women with acute stroke symptoms aged over 18 years.\n* Occlusion of the intracranial internal carotid artery, the middle cerebral artery, the anterior cerebral artery, the posterior cerebral artery, basilar artery and intracranial vertebral artery confirmed by CT, MR angiography, or digital subtraction angiography.\n* No absolute contraindication to iodinated contrast media.\n* Planned treatment with EVT by clinical care team.\n* Informed consent obtained from patients or their legal representatives.\n* Willing to be followed up as required by the clinical study protocol.\n\nExclusion Criteria:\n\n* Acute ischemic stroke occurs over 24 hours of time last known well.\n* Neurologic deficits caused by diagnoses other than ischemic stroke, such as intracerebral hemorrhage, subarachnoid hemorrhage, or intracranial tumors.\n* With other underlying factors leading to IAC, such as hyperthyroidism, end-stage renal disease, long-term oral intake of vitamin K antagonist(Warfarin), chronic vitamin D deficiency or overdose, persistent hypomagnesemia, persistent hypercalcemia, persistent hyperphosphatemia and high oral calcium intake.\n* Lack of non-contract CT images on admission and significant artifacts in CT images preventing IAC measurement.\n* Severe renal insufficiency (estimated glomerular filtration rate \\\u003C 30ml\u002Fmin or serum creatinine \\> 220μmol\u002FL (2.5mg\u002Fdl)).\n* Previous cerebrovascular intervention treatment or craniotomy.","ALL","18 Years",{"count":57,"type":58},434,"ESTIMATED","3 Years","OBSERVATIONAL","CAIS-MT is a single-center, prospective cohort study, to evaluate the correlation between outcomes of endovascular treatment(EVT) and intracranial artery calcification(IAC) in patients with acute ischemic stroke due to large or medium vessel occlusion.",[63,64,65,66,67,68,69,70,71],"Stroke, Acute","Ischemic Stroke","Vascular Diseases","Central Nervous System Diseases","Nervous System Diseases","Stroke","Brain Diseases","Cerebrovascular Disorders","Intracranial Arterial Calcification",[73,74,75,76,77,78,79],"Acute ischemic stroke","Large vessel occlusion","Mechanical thrombectomy","Endovascular treatment","Agatston score","Prospective cohort study","Intracranial atherosclerotic disease","2025-07-24",{"date":82,"type":83},"2025-07-28","ACTUAL",{"date":85,"type":83},"2024-03-28",{"date":87,"type":58},"2029-06",{"name":5,"class":6},1]