[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100536858":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":28,"locations":34,"responsibleParty":53,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Guy's and St Thomas' NHS Foundation Trust","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"RBD group",null,"Participants with a diagnosis of REM sleep behaviour disorder",[13],"Other: Exposure to contact sports or history of concussions",{"label":15,"type":10,"description":16,"interventionNames":17},"Control group","Participants without a diagnosis of REM sleep behaviour disorder",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Exposure to contact sports or history of concussions","History of contact sports practices or of concussions",[15,9],[24],{"name":25,"affiliation":26,"role":27},"Gillian Radcliffe","Guys and St. Thomas NHS Foundation Hospital","STUDY_CHAIR",[29],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Laura Pérez-Carbonell, PhD","CONTACT","02071883430","laura.perezcarbonell@gstt.nhs.uk",[35],{"facility":36,"status":37,"city":38,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Guy's & St Thomas' NHS Foundation Trust","RECRUITING","London","SE1 9RT","United Kingdom","UK",{"type":43,"coordinates":44},"Point",[45,46],-0.12574,51.50853,{"lat":46,"lon":45},[49],{"name":50,"role":31,"phone":51,"phoneExt":10,"email":52},"Gill Radcliffe","02071888070","gillian.radcliffe@gstt.nhs.uk",{"type":54,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100536858","the-cosp-rbd-study-concussions-and-contact-sports-in-rbd-vs-controls-100536858",false,"NCT06270290","The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls","Observational Cross-sectional Study Investigating the History of Concussion and Exposure to Contact Sports in Patients With REM Sleep Behaviour Disorder (RBD) Versus Controls (Without a Diagnosis of RBD)","COSP-RBD","Inclusion criteria group with RBD:\n\n* Patient at the SDC with diagnosis of RBD (Guy's and St Thomas' NHS Foundation Trust).\n* 50 years of age or above (patients below this age would not be expected to have a RBD related to a synucleinopathy and other causes of RBD would need to be considered instead - e.g. narcolepsy, post-traumatic stress disorder).\n\nInclusion criteria control group:\n\n* Patients who have undergone a v-PSG at the SDC (Guy's and St Thomas' NHS Foundation Trust) and who do not have history of suspected RBD or RBD confirmed by v-PSG.\n* 50 years of age or above This group will be age- and sex-matched to the RBD group.\n\nExclusion criteria group with RBD:\n\n* Age \\\u003C 50 years of age.\n* Diagnoses of narcolepsy or post-traumatic stress disorder.\n* Subjects lacking capacity or literacy.\n* Non-English speakers.\n\nExclusion criteria control group:\n\n* Age \\\u003C 50 years of age (in order to match RBD group).\n* REM sleep without atonia or confirmed RBD on v-PSG.\n* Diagnosis of neurological diseases, cognitive complaints or motor complaints.\n* Clinical history suggestive of parasomnia that may be included in the differential of RBD.\n* Subjects lacking capacity or literacy.\n* Non-English speakers.",true,"ALL","50 Years",{"count":67,"type":68},140,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate concussions and contact sports practices in REM sleep behaviour disorder (RBD).\n\nThe main questions it aims to answer are:\n\n* What is the proportion of patients with RBD that have a history of concussions or exposure to contact sports?\n* Is this proportion higher to that in control patients without a diagnosis of RBD?\n\nParticipants will undergo an interview with a sleep medicine specialist to answer questions about history of concussions and contact sports practices.\n\nResearchers will compare an RBD group and a control group (without RBD) to see if the proportion of concussions and exposure to contact sports differ.",[72,73],"REM Sleep Behavior Disorder","Concussion, Brain",[75,76,77],"REM sleep behaviour disorder","concussion","contact sports","2026-06-03",{"date":80,"type":81},"2026-06-04","ACTUAL",{"date":83,"type":81},"2024-04-23",{"date":85,"type":68},"2026-09-30",{"name":5,"class":6},1]