[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607784":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":10,"responsibleParty":26,"collaborators":10,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":10,"eligibilityCriteria":37,"healthyVolunteers":33,"sex":38,"minAge":39,"maxAge":10,"enrollmentInfo":40,"targetDuration":43,"studyType":44,"phases":10,"briefSummary":45,"conditions":46,"keywords":50,"overallStatus":56,"whyStopped":10,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":10},{"fullName":5,"class":6},"Herlev Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"CPH-MBD cohort",null,"Participants will be followed-up for 25 years after inclusion. Bone fractures, cardiovascular events, progression of kidney disease, end-stage kidney disease and death will be collected through linkage with registries during follow-up.\n\nThere is no intervention in this study.",{"label":13,"type":10,"description":14,"interventionNames":10},"Detailed dietary assessment","From the CPH-MBD cohort we invite 50 participants to complete a dietary assessment to obtain more accurate information about their calcium and phosphate intake.",[16],{"name":17,"affiliation":18,"role":19},"Ditte Hansen, Medical doctor, professor","Department of Nephrology, Herlev Hospital","STUDY_DIRECTOR",[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Freja S Hassager, Medical doctor","CONTACT","+4522554707","freja.staehr.hassager.01@regionh.dk",{"type":27,"investigatorFullName":28,"investigatorTitle":29,"investigatorAffiliation":30,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Freja Stæhr Hassager","Medical doctor","Herlev and Gentofte Hospital","100607784","the-cph-mbd-cohort-100607784",false,"NCT07193056","The CPH-MBD Cohort","Chronic Kidney Disease -Mineral and Bone Disorder, The CPH-MBD Cohort","Inclusion Criteria:\n\n* Age ≥18 years\n* CKD stage 4-5nonD (eGFR ≤ 29 ml\u002Fmin) according to KDIGO (Kidney Disease Improving Global Outcome) definition\n\nExclusion Criteria:\n\n* None","ALL","18 Years",{"count":41,"type":42},1000,"ESTIMATED","25 Years","OBSERVATIONAL","Persons with chronic kidney disease (CKD) have a 3-fold increased risk of bone fracture and a 10-fold increased risk of cardiovascular disease than the general population. These increased risks are related to the disturbances in the mineral metabolism, and this clinical entity is termed Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD).\n\nThe overall aim of the present project is to explore factors that may predict or associate with the development of bone and cardiovascular disease in patients with CKD and hopefully provide insight into underlying mechanisms and pathophysiological pathways for future treatment and prevention.\n\nIn a sub study investigators aim to explore the calcium and phosphate balance in patients with CKD and describe how these associate with each other as well as with kidney function (eGFR).",[47,48,49],"Chronic Kidney Disease Mineral and Bone Disorder","Chronic Kidney Disease (CKD)","Bone Markers",[51,52,53,54,55],"bone markers","parathyroid hormone","fracture risk","bone turnover","dietary assessment","NOT_YET_RECRUITING","2025-12-24",{"date":59,"type":60},"2025-12-31","ACTUAL",{"date":62,"type":42},"2025-12",{"date":64,"type":42},"2055-01",{"name":5,"class":6}]