[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100530349":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":30,"responsibleParty":47,"collaborators":19,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":19,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":19,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":19,"overallStatus":32,"whyStopped":19,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Air Force Military Medical University, China","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"100mg aspirin group","EXPERIMENTAL","Patients received oral 100mg aspirin, one tablet daily for 2 years",[13],"Drug: 100mg aspirin",[15],{"type":16,"name":17,"description":11,"armGroupLabels":18,"otherNames":19},"DRUG","100mg aspirin",[9],null,[21,26],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Yanglin Pan, MD","CONTACT","+8613991811225","yanglinpan@hotmail.com",{"name":27,"role":23,"phone":28,"phoneExt":19,"email":29},"Xiaoyu Kang, MD","+8615291680602","kangxiaoyu@hotmail.com",[31],{"facility":5,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Xi'an","Shaanxi","710032","China","CN",{"type":39,"coordinates":40},"Point",[41,42],108.92861,34.25833,{"lat":42,"lon":41},[45],{"name":22,"role":23,"phone":46,"phoneExt":19,"email":25},"13991811225",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Yanglin Pan","Professor","100530349","the-effect-of-aspirin-on-recurrent-acute-pancreatitis-100530349",false,"NCT06185621","The Effect of Aspirin on Recurrent Acute Pancreatitis","The Effect of 100mg Aspirin on Recurrent Acute Pancreatitis: a Prospective Cohort Study","Inclusion Criteria:\n\n* Patients with with recurrent acute pancreatitis\n\nExclusion Criteria:\n\n* Less than 2 episodes of acute pancreatitis in the past year\n* Latrogenic AP (pancreatitis due to endoscopic retrograde cholangiopancreatography, surgery, or after other invasive treatment). Iatrogenic pancreatitis will not count as an episode of recurrent pancreatitis\n* Previous allergy to Non-Steroid Anti-inflammatory Drugs (NSAIDs)\n* Regularly taking aspirin or other NSAIDs \\>3 doses per week\n* Contradictions for the medications of NSAIDs, including Active peptic ulcer disease or gastrointestinal hemorrhage within 3 months or previous peptic ulcer, history of significant hepatic or renal disease, platelet count less than 100X10\\^9\u002FL or international normalized ratio (INR) \\>1.5)\n* Biliary stones\n* Receiving endoscopic sphincterotomy and\u002For pancreatic stent placement and\u002For cholecystectomy and\u002For pancreatic surgery after the latest pancreatitis or planning to undergo one of those interventions within preceding 2 years\n* Patients with the level of serum triglycerides of \\>5.65 mmol\u002FL and did not receive regular lipid-lowering therapy\n* Primary hyperparathyroidism has been well-treated after last episode of pancreatitis and recruitment or will be operated in \\\u003C2 years\n* Patients with previously heavy alcohol consumption (50g\u002Fday for men, 40g\u002Fday for women) and have not quit drinking, or have significant withdrawal symptoms\n* Pregnant or breastfeeding patients\n* Inability to give informed consents","ALL","14 Years","80 Years",{"count":62,"type":63},23,"ESTIMATED","INTERVENTIONAL",[66],"NA","Recurrent acute pancreatitis (RAP) was defined as two or more occurrences of acute pancreatitis, which was associated with higher percentages of morbidities and mortalities, lower patients' life quality and increased health-care costs. Current interventions, including cholecystectomy and abstain from drinking were reported to be effective methods for preventing the recurrences of biliary and alcoholic etiologies, respectively. However, there were no effective preventions for other etiologies, such as idiopathic etiologies. Non-steroid anti-inflammatory drugs (NSAIDs), including indomethacin, diclofenac and aspirin could inhibiting the inflammatory cascade of pancreatitis. In this study, we aimed at exploring the effects of 100mg aspirin on reducing the occurrences of recurrent acute pancreatitis.",[69,70,71],"Recurrent Acute Pancreatitis","Prevention","Aspirin","2023-12-15",{"date":74,"type":75},"2023-12-29","ACTUAL",{"date":77,"type":75},"2023-11-01",{"date":79,"type":63},"2026-11-01",{"name":5,"class":6},1]