[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606165":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":41,"responsibleParty":61,"collaborators":11,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":11,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":11,"enrollmentInfo":73,"targetDuration":11,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":11,"overallStatus":43,"whyStopped":11,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Plymouth","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Chlorhexidine","EXPERIMENTAL",null,[13],"Other: Chlorhexidine mouthwash",{"label":15,"type":16,"description":11,"interventionNames":17},"Placebo","PLACEBO_COMPARATOR",[18],"Other: Placebo mouthwash",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"Chlorhexidine mouthwash","Rinsing the mouth with chlorhexidine mouthwash for 2 minutes before consuming 50 g of carbohydrates",[9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"Placebo mouthwash","Rinsing the mouth with placebo mouthwash for 2 minutes before consuming 50 g of carbohydrates",[15],[29],{"name":30,"affiliation":5,"role":31},"Raul Bescos Garcia","PRINCIPAL_INVESTIGATOR",[33,37],{"name":30,"role":34,"phone":35,"phoneExt":11,"email":36},"CONTACT","07599034710","Raul.Bescos@plymouth.ac.uk",{"name":38,"role":34,"phone":39,"phoneExt":11,"email":40},"Zoe Brookes","+44 1752 586828","Zoe.Brookes@plymouth.ac.uk",[42],{"facility":5,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Plymouth","Devon","PL4 8AA","United Kingdom","UK",{"type":50,"coordinates":51},"Point",[52,53],-4.14305,50.37153,{"lat":53,"lon":52},[56,58],{"name":57,"role":34,"phone":35,"phoneExt":11,"email":36},"Raul Bescos, PhD",{"name":59,"role":34,"phone":11,"phoneExt":11,"email":60},"Patricia Casas, PhD","Patricia.Casas@plymouth.ac.uk",{"type":31,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Raul Bescos","Associate Professor in Human Nutrition & Physiology","100606165","the-effect-of-chlorhexidine-mouthwash-on-postprandial-glucose-response-in-healthy-individuals-100606165",false,"NCT07172009","The Effect of Chlorhexidine Mouthwash on Postprandial Glucose Response in Healthy Individuals","Inclusion Criteria: Healthy adults (\\> 18 years\u002Fold)\n\nExclusion Criteria:\n\nThe main exclusion criteria is pregnancy, people following cancer treatment, taking immunosuppressant or antibiotics and using antibacterial mouthwash for less than 2 weeks before the study.",true,"ALL","18 Years",{"count":74,"type":75},45,"ESTIMATED","INTERVENTIONAL",[78],"NA","The digestion of carbohydrates begins in the mouth through the salivary enzyme amylase which breaks food starches into maltose and disaccharides. The mouth also has a large community of microorganisms which include bacteria, fungi, viruses and protozoa that can also assist in the digestion of carbohydrates. Mouthwashes containing antibacterial compounds such as chlorhexidine are used to kill oral bacteria, but current evidence indicates that a majority of these bacteria are essential for human health.\n\nThe aim of this study is to investigate whether chlorhexidine mouthwash can also affect the digestion of carbohydrates. At least 25 individuals will be recruited. Participants will visit the laboratory in two occasions. A saliva and blood sample (fingertip to measure blood glucose) will be taken at baseline. Then, using a randomized, cross-over and double-blind design, the participants will rinse their mouth for two minutes with a placebo or chlorhexidine mouthwash. Then, participants will eat 50 g of white bread and blood glucose will be measured (fingertips) every 30 min for the following 2 hours. Another saliva sample will be collected at the end of each test.",[81],"Glucose Metabolism Disorders (Including Diabetes Mellitus)","2025-09-12",{"date":84,"type":85},"2025-09-19","ACTUAL",{"date":87,"type":85},"2022-06-08",{"date":89,"type":75},"2026-06-01",{"name":5,"class":6},1]