[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633931":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":25,"responsibleParty":36,"collaborators":18,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":18,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":18,"maxAge":18,"enrollmentInfo":48,"targetDuration":18,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":61,"overallStatus":69,"whyStopped":18,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Nigde Omer Halisdemir University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental Group: Cold Gel Packs Application","EXPERIMENTAL","Women in the experimental group will apply cold gel packs to the acupoints located on the right and left sides of their bodies Sanyinjiao (SP6) and Hegu (Large Intestinal 4 (LI4)) for 15 minutes each, simultaneously, for a total of 30 minutes. This treatment will be administered over four weeks, comprising a total of 12 sessions, three days a week. Prior to the treatment, the acupoints on the woman's hands and legs will be identified by a researcher who has completed a course in 'acupressure' and marked with a permanent marker. The treatment steps, developed in accordance with the literature, will be explained in detail.\n\nIt will be emphasized that cold gel packs should be kept in the freezer compartment of the refrigerator for at least 2 hours before application, and that they should be removed and placed in a protective cover before application. A reminder message will be sent to the woman by the researcher before the session.",[13],"Behavioral: Cold gel packs application",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","NO_INTERVENTION","No intervention will be applied.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Cold gel packs application","The women will apply a cold gel pack to the Sanyinjiao (SP6) and Hegu (Large Intestinal 4 (LI4)) acupoints located on the right and left sides of the body, which have been marked with a permanent marker by a specialist researcher.\n\nEach session will last a total of 30 minutes: 15 minutes on the SP6 acupoints followed by 15 minutes on the LI4 acupoints.This treatment will be carried out three times a week for four weeks, comprising a total of 12 sessions.",[9],[26],{"facility":27,"status":18,"city":28,"state":18,"zip":18,"country":29,"countryCode":18,"cosmosGeoPoint":30,"geoPoint":35,"contacts":18},"Başkent Üniversitesi Hastanesi","Ankara","Turkey (Türkiye)",{"type":31,"coordinates":32},"Point",[33,34],32.85427,39.91987,{"lat":34,"lon":33},{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","Rabia Atilla","Assistant Professor","100633931","the-effect-of-cold-packs-on-hot-flushes-and-depression-in-women-going-through-the-climacteric-period-100633931",false,"NCT07533097","The Effect of Cold Packs on Hot Flushes and Depression in Women Going Through the Climacteric Period","The Effect of Applying Cold Gel Packs to the LI4 and SP6 Acupoints on Menopausal Hot Flashes and Depression in Women During the Climacteric Period","Inclusion Criteria:\n\n* In the perimenopausal phase (no menstruation for 3-11 months or an increase in irregular menstrual bleeding) or the postmenopausal phase (no menstruation for more than 12 months),\n* Participants experiencing moderate to severe hot flushes at least four times a day in the week prior to enrolment,\n* Participants who are literate in Turkish and able to communicate,\n* Participants who volunteer to take part in the study will be included in the study.\n\nExclusion Criteria:\n\n* Women who have entered menopause following surgery,\n* Women whose hot flush symptoms have decreased or ceased in the week prior to joining the study,\n* Those receiving hormone replacement therapy,\n* Those who had received herbal medication (such as black cohosh, black cohosh, ginkgo, ginseng, motherwort, valerian, black snake root, St. John's wort, etc.) or chemical medication for at least two weeks prior to joining the study,\n* Women with endocrine system disorders such as diabetes or a condition presenting symptoms similar to hot flushes,\n* Women with a regular menstrual cycle,\n* Women with a psychiatric diagnosis who are currently receiving treatment,\n* Women taking sleeping pills,\n* Women with a language barrier preventing communication in Turkish,\n* Women who are not willing to participate in the study will not be included in the research.","FEMALE",{"count":49,"type":50},80,"ESTIMATED","INTERVENTIONAL",[53],"NA","This study is planned as a pre-post test, randomised controlled, experimental trial designed to determine the effect of applying a cold gel pack to the Sanyinjiao (SP6) and Hegu (Large Intestinal 4 (LI4)) acupoints on hot flushes and depression in women during the climacteric period.",[56,57,58,59,60],"Hot Flashes","Climactericum","Perimenopausal Depression","Cold Application","Acupoints",[62,63,64,65,66,67,68],"Climacterium","hot flashes","perimenopausal depression","cold gel packs","cold application","LI4 acupoint","SP6 acupoint","NOT_YET_RECRUITING","2026-04-16",{"date":72,"type":73},"2026-04-21","ACTUAL",{"date":75,"type":50},"2026-04-13",{"date":77,"type":50},"2026-09-13",{"name":38,"class":6},1]