[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100585204":3},{"organization":4,"armGroups":7,"interventions":34,"overallOfficials":33,"centralContacts":47,"locations":53,"responsibleParty":70,"collaborators":72,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":33,"eligibilityCriteria":82,"healthyVolunteers":83,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":33,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":33,"overallStatus":96,"whyStopped":33,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Unilever R&D","INDUSTRY",[8,14,18,22,26,30],{"label":9,"type":10,"description":11,"interventionNames":12},"Cosmetic product M68","EXPERIMENTAL","Cosmetic product to be applied twice daily 6 days a week (except on measurement days, when it will be applied once) for the duration of the study.",[13],"Other: Cosmetic product M68",{"label":15,"type":10,"description":11,"interventionNames":16},"Cosmetic product Z15",[17],"Other: Cosmetic product Z15",{"label":19,"type":10,"description":11,"interventionNames":20},"Cosmetic product R52",[21],"Other: Cosmetic product R52",{"label":23,"type":10,"description":11,"interventionNames":24},"Cosmetic product J61",[25],"Other: Cosmetic product J61",{"label":27,"type":10,"description":11,"interventionNames":28},"Cosmetic product U36",[29],"Other: Cosmetic product U36",{"label":31,"type":32,"description":31,"interventionNames":33},"No treatment control","NO_INTERVENTION",null,[35,39,41,43,45],{"type":36,"name":9,"description":37,"armGroupLabels":38,"otherNames":33},"OTHER","Cosmetic skin brightening product to be applied to defined test site",[9],{"type":36,"name":15,"description":37,"armGroupLabels":40,"otherNames":33},[15],{"type":36,"name":19,"description":37,"armGroupLabels":42,"otherNames":33},[19],{"type":36,"name":23,"description":37,"armGroupLabels":44,"otherNames":33},[23],{"type":36,"name":27,"description":37,"armGroupLabels":46,"otherNames":33},[27],[48],{"name":49,"role":50,"phone":51,"phoneExt":33,"email":52},"Dr Mukta Sachdev, MD","CONTACT","+91 8040917243","mukta.sachdev@msclinical.com",[54],{"facility":55,"status":33,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"MS Clinical Research Pvt Ltd","Bangalore","Karnataka","560008","India","IN",{"type":62,"coordinates":63},"Point",[64,65],77.59369,12.97194,{"lat":65,"lon":64},[68],{"name":49,"role":50,"phone":69,"phoneExt":33,"email":52},"+91 80 40917243",{"type":71,"investigatorFullName":33,"investigatorTitle":33,"investigatorAffiliation":33,"oldNameTitle":33,"oldOrganization":33},"SPONSOR",[73],{"name":74,"class":75},"MS Clinical Research Pvt. Ltd","UNKNOWN","100585204","the-effect-of-cosmetic-products-on-skin-brightening-100585204",false,"NCT06899321","The Effect of Cosmetic Products on Skin Brightening","A Clinical Study to Evaluate Test Products for Skin Brightening Benefit Under Controlled UV Exposure, in a 6-week Study Design","Inclusion Criteria:\n\n* Healthy female adult participants in general good health as determined from a recent medical history.\n* Participants in the age group of 18-45 years as on the day of enrolment (both ages inclusive).\n* Participants having very little hair, no burns, no cut\u002Fabrasion; no moles\u002Ftattoo\u002Fbirth marks\u002Fburn marks on the test sites\u002Fareas as identified on screening.\n* Participants with long and broad forearms.\n* Participants having skin photo-type IV and V.\n* Participants with Spectrophotometer L\\* value- 45 to 55 (both values included) on the identified test sites on the volar forearm.\n* Participants having uniform skin color and no sunburn\u002F erythema on the test sites.\n* Participants who do not have very dry or scaly skin, uneven skin tone on their volar forearms or no other signs of significant local irritation or skin disease like psoriasis.\n* Participants who agree to refrain from using pumice stone, scrubber while bathing during the study.\n* Participants who are willing to avoid direct sun exposure to the test sites.\n* Participants who have not participated in any clinical product evaluation test within past 1 month.\n* Participants able to read and sign an appropriate informed consent form indicating her willingness to participate and agree to come for regular study visits.\n* Participants willing to abide by and comply with the study protocol.\n* Participants willing to use umbrella \\& wear full covered attire if she has to go in sun.\n* Participants who are willing not to participate in any other clinical study during participation in the current study.\n\nExclusion Criteria:\n\n* Participants with a known history or present condition of allergic response to any sunscreen products, cosmetic products, bathing soaps, detergent powder or medicine.\n* Participants who have outdoor job, extremely physical (manual) job which could cause excessive sun exposure or sweating\n* Participants who are smokers.\n* Menopausal women.\n* Participants having active skin diseases which will interfere with the test readings.\n* Participants on oral and topical medications (e.g Steroids, anti-oxidant, antibiotics) which will compromise the study.\n* Systemic treatment which may modify the cutaneous state on the day of inclusion or in the previous 30 days, including retinoid therapy.\n* Participants who are pregnant, lactating or nursing.\n* Intense sun exposure\u002F photo allergenicity\u002Ftoxicity.\n* Chronic illness which may influence the cutaneous state.\n* Participants participating in any other cosmetic or therapeutic trial.\n* Participants with any underlying uncontrolled medical illness including diabetes mellitus, hypertension, liver disease or history of alcoholism, HIV, hepatitis, or any other serious medical illness that will pose a health risk due to study participation as per investigator's discretion.\n* For female participants only: be pregnant, planning pregnancy or lactating\u002Fnursing. Urine pregnancy testing (UPT) will be performed at the time of screening.",true,"FEMALE","18 Years","45 Years",{"count":88,"type":89},34,"ESTIMATED","INTERVENTIONAL",[92],"NA","This is a single centre, single cell, blinded study designed to evaluate the effect of 5 cosmetic products on skin brightening, skin hydration and skin barrier function of the volar forearm after controlled UV exposure as compared to baseline and a no-treatment control.",[95],"Skin Brightening","NOT_YET_RECRUITING","2025-03-20",{"date":99,"type":100},"2025-03-27","ACTUAL",{"date":102,"type":89},"2025-03",{"date":104,"type":89},"2025-05",{"name":5,"class":6},1]