[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608186":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":33,"centralContacts":43,"locations":49,"responsibleParty":62,"collaborators":33,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":33,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":52,"whyStopped":33,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Recep Tayyip Erdogan University","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Conventional Suturing","EXPERIMENTAL","Wound edges are approximated using 3\u002F0 braided, non-absorbable silk sutures (Doğsan®, Turkey). Standard oral surgery closure technique.",[13],"Procedure: Conventional Suturing",{"label":15,"type":10,"description":16,"interventionNames":17},"Sutureless Technique","The wound is left to heal by secondary intention without any suturing material.",[18],"Procedure: Sutureless Technique",{"label":20,"type":10,"description":21,"interventionNames":22},"Surgical Drain","A biocompatible sterile plastic drain is placed to facilitate drainage of blood and fluids from the surgical site",[23],"Procedure: Surgical Drain",{"label":25,"type":10,"description":26,"interventionNames":27},"Cyanoacrylate Tissue Adhesive","Cyanoacrylate-based medical tissue adhesive (PeriAcryl®90 High Viscosity) is applied to effectively close the wound edges.",[28],"Procedure: Cyanoacrylate Tissue Adhesive",[30,34,37,40],{"type":31,"name":9,"description":11,"armGroupLabels":32,"otherNames":33},"PROCEDURE",[9],null,{"type":31,"name":15,"description":35,"armGroupLabels":36,"otherNames":33},"The wound is left to heal by secondary intention without using any suturing material.",[15],{"type":31,"name":20,"description":38,"armGroupLabels":39,"otherNames":33},"A biocompatible sterile plastic drain is placed in the surgical site to facilitate drainage of blood and fluids, helping to reduce edema and hematoma formation.",[20],{"type":31,"name":25,"description":41,"armGroupLabels":42,"otherNames":33},"Cyanoacrylate-based medical tissue adhesive (PeriAcryl®90 High Viscosity) is applied to the wound edges, providing rapid polymerization and effective closure.",[25],[44],{"name":45,"role":46,"phone":47,"phoneExt":33,"email":48},"Alperen Kalyoncu, Assistant Professor","CONTACT","+905058261967","alperen.kalyoncu@erdogan.edu.tr",[50],{"facility":51,"status":52,"city":53,"state":54,"zip":33,"country":55,"countryCode":33,"cosmosGeoPoint":56,"geoPoint":61,"contacts":33},"Recep Tayyip Erdoğan University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery","RECRUITING","Rize","Rize Province","Turkey (Türkiye)",{"type":57,"coordinates":58},"Point",[59,60],40.52194,41.02083,{"lat":60,"lon":59},{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"PRINCIPAL_INVESTIGATOR","Alperen Kalyoncu","Assistant Professor","100608186","the-effect-of-different-flap-closure-techniques-on-postoperative-morbidity-in-impacted-third-molar-surgery-100608186",false,"NCT07198282","The Effect of Different Flap Closure Techniques on Postoperative Morbidity in Impacted Third Molar Surgery","The Effect of Different Flap Closure Techniques on Postoperative Morbidity: A Randomized Controlled Trial for Impacted Third Molar Surgery","GMC02","Inclusion Criteria:\n\n* Patients aged 18-40 years.\n* Patients with no systemic diseases (ASA I).\n* Patients with impacted mandibular third molars indicated for extraction, with bone and\u002For mucosal retention, in similar positions (Pell \\& Gregory Class 2, Position B; Winter classification vertical or mesioangular).\n\nExclusion Criteria:\n\n* Patients classified as ASA II, III, or IV.\n* Known allergy to anesthetic solutions.\n* Allergy to acrylate.\n* Pregnant or breastfeeding women.\n* Individuals with tobacco use ≥10 cigarettes\u002Fday.\n* Alcohol users.\n* Patients using antiplatelet agents.\n* Patients using anticoagulants.\n* Patients with coagulation disorders.\n* Patients with immunosuppressive diseases or receiving immunosuppressive therapy.\n\nPatients with acute pain or local infection at the surgical site.","ALL","18 Years","40 Years",{"count":78,"type":79},148,"ESTIMATED","INTERVENTIONAL",[82],"NA","1\\. ABSTRACT This study is a randomized controlled trial comparing the clinical efficacy and safety of four different flap closure techniques in reducing postoperative morbidity (pain, swelling, trismus, wound healing) and improving patient quality of life (GOHAI) following impacted mandibular third molar extraction. The methods include conventional suturing, sutureless technique, surgical drain, and cyanoacrylate tissue adhesive, which are commonly used in oral surgery practice. The study aims to scientifically evaluate the effects of each method on patients and to determine the most appropriate clinical approach.",[85,86,87],"Impacted Mandibular Third Molar","Postoperative Morbidity","Oral Surgery",[89,90,91,92,93],"Impacted third molar","Flap closure techniques","Cyanoacrylate","Sutureless technique","Surgical drain","2026-06-08",{"date":96,"type":97},"2026-06-09","ACTUAL",{"date":99,"type":97},"2026-05-08",{"date":101,"type":79},"2026-08-30",{"name":5,"class":6},1]