[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597090":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":36,"responsibleParty":56,"collaborators":18,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":18,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":68,"enrollmentInfo":69,"targetDuration":18,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":81,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"The University of Texas Health Science Center at San Antonio","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1: Experimental Group using EMD","EXPERIMENTAL","During implant uncovering the experimental group will receive EMD under the buccal flap",[13],"Device: Enamel Matrix Derivative",{"label":15,"type":16,"description":17,"interventionNames":18},"Group 2: Control Group","NO_INTERVENTION","No EMD is administered under the buccal flap during suturing",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Enamel Matrix Derivative","EMD is an FDA approved medical device used in periodontal procedures since 1996. It has been shown to enhance soft and hard tissue healing, increased root coverage and aid in periodontal regeneration. It's use as an adjunct during implant uncovering may increase peri-implant mucosal thickness.",[9],[26],"EMD",[28],{"name":29,"affiliation":5,"role":30},"Angela Palaiologou-Gallis, DDS","PRINCIPAL_INVESTIGATOR",[32],{"name":29,"role":33,"phone":34,"phoneExt":18,"email":35},"CONTACT","210-450-3715","PalaiologouA@uthscsa.edu",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"University of Texas Health Science Center at San Antonio","RECRUITING","San Antonio","Texas","78229","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-98.49363,29.42412,{"lat":49,"lon":48},[52],{"name":53,"role":33,"phone":54,"phoneExt":18,"email":55},"Angela A Palaiologou-Gallis, DDS., MS.","210-567-3567","palaiologoua@uthscsa.edu",{"type":30,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Angela Palaiologou-Gallis, DDS, MS","Professor","100597090","the-effect-of-enamel-matrix-derivatives-on-gingival-tissue-thickness-100597090",false,"NCT07053969","The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness","The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness. A Randomized Controlled Trial.","Inclusion Criteria:\n\n1. Ability of subject to understand and the willingness to sign a written informed consent document.\n2. Males and females; Age 18 to 89 years old\n3. Require second stage implant uncovering\n4. In either the maxillary or mandibular arch\n5. Has consistent transportation for all clinical and study visits\n\nExclusion Criteria:\n\n1. Pregnancy, or those planning to become pregnant\n2. Allergy or any medical issue using EMD\n3. Non-English speaking\n4. Patients on anticoagulants\n5. Patients who object to the use of animal products",true,"ALL","18 Years",{"count":70,"type":71},32,"ESTIMATED","INTERVENTIONAL",[74],"NA","Scientists do research to answer important questions which might help change or improve the way we do things in the future.\n\nThe investigators know that using Enamel Matrix Derivatives results in thicker gum tissues around teeth. This study will test to see if using EMD around implants results in thicker gum tissues around implants.",[77,78,79,80],"Dental Implantation","Missing Teeth","Periodontitis, Adult","Mucositis",[82,26,83,84],"Enamel Matrix Derivatives","Keratinized mucosa width","Mucosal thickness","2025-11-10",{"date":87,"type":88},"2025-11-12","ACTUAL",{"date":90,"type":88},"2025-08-31",{"date":92,"type":71},"2027-09",{"name":5,"class":6},1]