[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603149":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":50,"collaborators":26,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":56,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":26,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":41,"whyStopped":26,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Pamukkale University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"ESWT + Conventional Physical Therapy Group","EXPERIMENTAL","A total of 6 sessions of extracorporeal shock wave therapy (ESWT) will be administered twice a week, along with 15 sessions of conventional physical therapy applied five times per week. Each conventional physical therapy session will include 20 minutes of hot pack application, 20 minutes of conventional transcutaneous electrical nerve stimulation (TENS), 5 minutes of ultrasound therapy at an intensity of 1.5 W\u002Fcm², and core stabilization exercises performed under the supervision of a physiotherapist. The treatment program will be carried out over a total period of 3 weeks. Each ESWT session will last approximately 15 minutes. ESWT will be applied with the patient positioned in the prone position, using an energy density of 0.15 mJ\u002Fmm², at a frequency of 4 Hz, and delivering 1,500 shock waves per session. The application will target the right and left paravertebral muscles between the L3 and S1 spinal segments.",[13,14],"Device: Radial Extracorporeal Shock Wave Therapy","Other: Conventional rehabilitation",{"label":16,"type":17,"description":18,"interventionNames":19},"Conventional Physical Therapy Group","ACTIVE_COMPARATOR","A total of 15 sessions of conventional physical therapy will be administered, five times per week. Each session will include 20 minutes of hot pack application, 20 minutes of conventional transcutaneous electrical nerve stimulation (TENS), 5 minutes of ultrasound therapy at 1.5 W\u002Fcm², and core stabilization exercises performed under the supervision of a physiotherapist. The treatment will be applied over a total period of 3 weeks.",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Radial Extracorporeal Shock Wave Therapy","A total of 6 sessions of ESWT, applied twice a week. Each ESWT session will last approximately 15 minutes. ESWT will be administered with the patient in the prone position, using an energy density of 0.15 mJ\u002Fmm², at 4 Hz frequency, and 1,500 shock waves per session.\n\nThe ESWT application will be performed on the right and left paravertebral muscles between the L3 and S1 segments.",[9],null,{"type":6,"name":28,"description":18,"armGroupLabels":29,"otherNames":26},"Conventional rehabilitation",[16,9],[31],{"name":32,"affiliation":5,"role":33},"Füsun Ardıç, Professor","STUDY_DIRECTOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":26,"email":38},"CONTACT","+905342197714","ardicf@gmail.com",[40],{"facility":5,"status":41,"city":42,"state":26,"zip":26,"country":43,"countryCode":26,"cosmosGeoPoint":44,"geoPoint":49,"contacts":26},"RECRUITING","Denizli","Turkey (Türkiye)",{"type":45,"coordinates":46},"Point",[47,48],29.0875,37.77417,{"lat":48,"lon":47},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Füsun Ardıç","PROFESSOR","100603149","the-effect-of-eswt-added-to-conservative-treatment-on-pain-disability-and-ultrasonographic-outcomes-in-chronic-low-back-pain-100603149",false,"NCT07132762","The Effect of ESWT Added to Conservative Treatment on Pain, Disability, and Ultrasonographic Outcomes in Chronic Low Back Pain","The Effect of Extracorporeal Shock Wave Therapy (ESWT) Added to Conservative Treatment on Pain, Disability, and Ultrasonographic Outcomes in Chronic Low Back Pain: A Randomized Controlled Trial","ESWT","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Non-specific low back pain lasting more than three months\n\nExclusion Criteria:\n\n* Specific lumbar spine diseases (radicular pain, spinal stenosis, infection)\n* History of trauma, fracture, surgery, or presence of scar tissue in the lumbar region\n* Presence of a disease that may affect muscle stiffness, such as collagen tissue disorders, hemiplegia, multiple sclerosis, or myopathies\n* Malignancy, pregnancy, severe hypertension\n* Coagulopathy, chronic heart disease\n* Ankylosing spondylitis\n* Diseases that may initially affect lumbar mobility and pain, such as leg length discrepancy, hip prosthesis, or scoliosis","ALL","18 Years","65 Years",{"count":66,"type":67},44,"ESTIMATED","INTERVENTIONAL",[70],"NA","Chronic low back pain (CLBP) is a major public health concern worldwide, leading to reduced quality of life and significant work loss. It is defined as pain lasting more than 12 weeks between the lumbar and sacral spinal segments. The global prevalence of CLBP ranges from 13.1% to 20.3%, and the number of affected individuals has increased from 370 million in 1990 to 570 million in 2017.\n\nCore muscles, including the multifidus, erector spinae, transversus abdominis, psoas major, and quadratus lumborum, play a key role in spinal stabilization. In patients with CLBP, dysfunction and loss of synergy among these muscles can compromise spinal balance. Prolonged poor posture can reduce the strength and endurance of the lumbar erector spinae, multifidus, and transversus abdominis, leading patients to compensate by overusing the erector spinae, rectus abdominis, and oblique abdominal muscles. This compensation is considered one of the primary contributors to chronic low back pain.\n\nThese deep core muscles can be objectively evaluated using ultrasonography (USG), a non-invasive, inexpensive, and accessible imaging method. Strain elastography, a quantitative ultrasonographic technique, is increasingly used to assess tissue stiffness and monitor structural changes in muscle over time.\n\nConventional treatments for CLBP include pharmacotherapy, exercise, and physical therapy. In recent years, extracorporeal shock wave therapy (ESWT) has emerged as a non-invasive, easily applicable, and low-risk treatment method. ESWT is widely used in various musculoskeletal conditions such as lateral epicondylitis, patellar tendinopathy, and calcific tendinitis of the shoulder. Studies have shown that ESWT provides pain relief and functional improvement in patients with CLBP through its angiogenic, anti-inflammatory, analgesic, and tissue-regenerative effects.\n\nSeveral studies have demonstrated the positive impact of ESWT on pain reduction and functional recovery in CLBP. A recent meta-analysis reported that ESWT significantly reduces pain in CLBP patients and may be superior to other conservative treatments. Yue et al. (2021) highlighted the short-term benefits of ESWT in reducing pain and disability, while also emphasizing the need for well-designed randomized controlled trials (RCTs) to establish high-quality evidence. Similarly, Wu et al. (2023) underscored the necessity of including objective outcomes in future RCTs to better evaluate the efficacy of ESWT.\n\nAlthough numerous studies have assessed the effects of ESWT on pain, disability, and functional outcomes in CLBP, to date, no study has objectively evaluated its effectiveness using ultrasonographic strain elastography focusing on the elasticity and stiffness of core muscles.\n\nThis study aims to be one of the first to assess the long-term effects of ESWT using objective measures. Its contribution to the literature lies in evaluating the efficacy of ESWT, when added to conventional physical therapy, through long-term monitoring with ultrasonographic strain elastography in patients with CLBP.",[73],"Chronic Low Back Pain",[75,76,77,78],"Extracorporeal Shockwave Therapy treatment (ESWT)","Elastography","physical therapy","chronic low back pain","2026-02-04",{"date":81,"type":82},"2026-02-06","ACTUAL",{"date":84,"type":82},"2025-10-10",{"date":86,"type":67},"2026-09-15",{"name":5,"class":6},1]