[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643713":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":54,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":25,"overallStatus":75,"whyStopped":25,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Zhongshan Ophthalmic Center, Sun Yat-sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"glass rod group","EXPERIMENTAL","Implement glass rod assisted eyelid massage for a total of 4 times",[13],"Procedure: glass rod assisted eyelid massage",{"label":15,"type":10,"description":16,"interventionNames":17},"eyelid support plate group","Implement eyelid support plate assisted eyelid massage for a total of 4 times.",[18],"Procedure: eyelid support plate assisted eyelid massage",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","eyelid support plate assisted eyelid massage","The participants of experimental group receive sodium hyaluronate eye drops in both eyes four times a day for 8 weeks, and receive eyelid support plate assisted eyelid massage based on the group standard of Meibomian gland massage procedure (T\u002FGDPMAA003-2023) every two weeks for a total of four times. Follow up evaluations will be conducted at weeks 4 and 8.",[15],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"glass rod assisted eyelid massage","The participants of control group receive sodium hyaluronate eye drops 4 times a day for 8 weeks, and receive glass rod assisted eyelid massage based on the group standard of \"Meibomian gland massage operation procedure\" (T\u002FGDPMAA003-2023) every 2 weeks, for a total of 4 times. Follow up evaluations will be conducted at weeks 4 and 8",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Qi Fu","CONTACT","86+66619334","fuqi@gzzoc.com",[37],{"facility":38,"status":25,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Zhongshan Ophthalmology Center, Sun Yat sen University","Guangzhou","Guangdong","510060","China","CN",{"type":45,"coordinates":46},"Point",[47,48],113.25,23.11667,{"lat":48,"lon":47},[51],{"name":52,"role":33,"phone":34,"phoneExt":25,"email":53},"Bishan Tian","tianbishan@gzzoc.com",{"type":55,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100643713","the-effect-of-eyelid-support-plate-assisted-eyelid-massage-on-meibomian-gland-dysfunction-a-randomized-controlled-trial-100643713",false,"NCT07633938","The Effect of Eyelid Support Plate Assisted Eyelid Massage on Meibomian Gland Dysfunction: a Randomized Controlled Trial","Inclusion Criteria:\n\n1. Voluntarily participate and sign an informed consent form;\n2. Age range: 18 to 60 years old;\n3. Meet the diagnostic criteria for dry eye in the International Society of Tears and Ocular Surface (TFOS) Dry Eye Symposium (DEWS) II ;\n4. 1\u002F3 or more of the meibomian gland openings are blocked or the secretion characteristics of the meibomian gland are abnormal;\n5. The best corrected visual acuity for each eye is ≥ 0.5;\n6. Eye pressure (IOP) ≥ 5mmHg and ≤ 21mmHg per eye;\n7. Women with reproductive potential agree to use reliable contraceptive methods during the study period;\n8. Willing and able to complete all planned research visits and follow the guidance of the researchers.\n\nExclusion Criteria:\n\n1. Contact lens use: Having used contact lenses within 14 days prior to the screening visit, or refusing to commit to discontinuing contact lens use during the study period (within the next 2 months);\n2. Had undergone corneal refractive surgery (e.g., LASIK\u002FSMILE), other corneal surgeries, cataract surgery, anti-glaucoma surgery, or fundoscopic surgery within 12 months prior to enrollment screening;\n3. Participation in other medical studies within 3 months prior to enrollment screening;\n4. Presence of any of the following active ocular diseases at present or within 3 months prior to screening: I) Acute allergic conjunctivitis; II) Infection (by bacteria, viruses, fungi, etc.); III) Inflammation (e.g., keratitis, retinitis).\n\n   Meningitis, choroiditis, uveitis, scleritis, etc.;\n5. Eyelid abnormalities affecting eyelid function (such as ptosis, blepharospasm, entropion, ectropion, etc.);\n6. Extensive ocular surface scars or conditions that may compromise ocular surface integrity (e.g., Stevens-Johnson syndrome, history of chemical burns, persistent corneal epithelial defects, history of ocular trauma, etc.);\n7. Currently or previously diagnosed with glaucoma, or undergoing treatment with anti-glaucoma medications;\n8. Has used any of the following ocular medications within the past 1 month: immunosuppressants, nonsteroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, or perfluorohexyloctane;\n9. Has received any of the following non-pharmacological treatments for dry eye within the past month: meibomian gland massage, deep eyelid margin cleansing, intense pulsed light therapy, or thermal pulsation therapy;\n10. During pregnancy or lactation;\n11. Neurological or psychiatric disorders (moderate to severe anxiety, depression, and sleep disorders);\n12. Uncontrolled ocular or systemic diseases;\n13. History of epilepsy;\n14. The investigator determines that the subject is not suitable for participation in this study.","ALL","18 Years","60 Years",{"count":66,"type":67},142,"ESTIMATED","INTERVENTIONAL",[70],"NA","This study aims to conduct a randomized controlled clinical trial to compare the efficacy of a new type of massage device - eyelid support plate and glass rod assisted eyelid massage in improving MGD related dry eye symptoms, and evaluate the comfort and efficiency of both treatments, providing evidence-based support for clinical work",[73,74],"Dry Eye Disease (DED)","MGD-Meibomian Gland Dysfunction","NOT_YET_RECRUITING","2026-06-08",{"date":78,"type":79},"2026-06-11","ACTUAL",{"date":81,"type":67},"2026-07-01",{"date":83,"type":67},"2027-09-01",{"name":5,"class":6},1]