[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622169":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":33,"locations":25,"responsibleParty":43,"collaborators":25,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":25,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":25,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":66,"whyStopped":25,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":25},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Functional crown lengthening","EXPERIMENTAL","patients will undergo functional crown lengthening by raising a full thickness flap with osseous resection to establish a distance of 3 mm between the cervical margin of the cavity and the bone crest. Osteoplasty was performed in the adjacent and neighboring tooth surfaces to accomplish a smooth bone contour. The flaps will then be sutured in their new position",[13],"Procedure: Functional Crown lengthening",{"label":15,"type":16,"description":17,"interventionNames":18},"Deep Margin Elevation","ACTIVE_COMPARATOR","patients will undergo deep margin elevation through a two-step direct restoration performed using the concepts of Progressive Matrixing and Wedging where the Deep subgingival cavity margin will be acquired. Then isolation by rubber dam. A curved matrix will seal the margin without any gingival or rubber dam entrapped in between. One step adhesive system will be performed under rubber dam isolation. Composite resin base is applied to raise the margin by about 2 mm. A bulk fill packable or flowable composite can be used. Finishing will be done using polishing strips and disks. Finally a bitewing radiograph will be taken to check the presence of overhangs or gaps before the final restoration.",[19],"Procedure: Deep Margin Elevation",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Functional Crown lengthening",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":27,"otherNames":25},[15],[29],{"name":30,"affiliation":31,"role":32},"Doaa A. Khattab, Associate Professor","Faculty of Dentistry - Ain shams university","STUDY_DIRECTOR",[34,40],{"name":35,"role":36,"phone":37,"phoneExt":38,"email":39},"Mahmoud A. Ezz, Bachelor","CONTACT","+201092921800","+201091702356","mahmoudezz210000@gmail.com",{"name":41,"role":36,"phone":42,"phoneExt":25,"email":25},"Hadeel G. Al Malahy, Associate Professor","+201017767662",{"type":44,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100622169","the-effect-of-functional-crown-lengthening-versus-deep-margin-elevation-on-periodontal-tissues-100622169",false,"NCT07380126","The Effect of Functional Crown Lengthening Versus Deep Margin Elevation on Periodontal Tissues","The Effect of Functional Crown Lengthening Versus Deep Margin Elevation on Periodontal Tissues (A Randomized Clinical Trial With Biochemical Analysis)","Inclusion Criteria :\n\n1. Patients aged 20-50 years\n2. Both genders\n3. Patients free from any systemic disease that may affect the treatment (Greenberg \\& Glick, 2012)\n4. Patients with intact periodontium\n5. Patients are ready to comply with oral hygiene measures.\n6. Patients having Posterior teeth with carious cavities and\u002F or restorations in need of replacement on proximal surfaces, where the cervical margin of the cavity is at a distance less than 3 mm to the bone crest (Cyana et al.,2013).\n7. Patients with thick phenotype having gingival thickness \\> 1mm (Aimetti et al,2008).\n8. Patients with keratinized tissue width ≥ 2mm\n\nExclusion criteria:\n\n1. Pregnant and lactating females\n2. Smokers\n3. Drug abusers.\n4. Patients with persistent poor oral hygiene\n5. Patients with proximal margins beyond the bone level\n6. Patients with developmental dental anomalies\n7. Patients undergoing or will start orthodontic treatment","ALL","20 Years","50 Years",{"count":56,"type":57},20,"ESTIMATED","INTERVENTIONAL",[60],"NA","The present study will evaluate and compare the effect of functional CL and DME in the treatment of posterior teeth with class II caries clinically and on the level of TNF-α in the GCF of treated teeth.\n\nClinical evaluation of periodontal tissue in the form of probing depth as a primary outcome, clinical attachment level, plaque index, bleeding index, gingival index, pink aesthetic score, Radiographic evaluation of biological width and the level of TNF-α in the GCF as a secondary outcome.",[63],"TNF Alpha",[23,15,65],"TNF-α","NOT_YET_RECRUITING","2026-01-24",{"date":69,"type":70},"2026-02-02","ACTUAL",{"date":72,"type":57},"2026-02-01",{"date":74,"type":57},"2026-10-01",{"name":5,"class":6}]