[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614021":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":51,"collaborators":19,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":19,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":19,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":19,"overallStatus":36,"whyStopped":19,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Uşak University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Forced expiration program","EXPERIMENTAL","The participants will be equipped with the Airofit respiratory muscle trainer and will be provided with standardised instructions on performing forced expiration manoeuvres.\n\nParticipants will be fitted with the Airofit respiratory muscle trainer and given standardized instructions on performing forced expiration maneuvers.\n\n* The protocol consisted of sequentially performing forced expiration at each of the device's six predefined resistance levels (Level 1 being the lowest, Level 6 the highest).\n* The sequence for each level will be identical and as follows:\n\n  * Exercise Phase: The participant will perform forced expiration maneuvers with the Airofit device for a duration of 5 minute at the specified resistance level.\n  * Immediate Post-Exercise Measurement: Within 5 seconds of completing the exercise minute, IOP will be measured. This measurement will be labeled accordingly: T1 (after Level 1), T2 (after Level 2), up to T6 (after Level 6).",[13],"Other: Intraocular Pressure after forced expiration",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Intraocular Pressure after forced expiration","The experiment will entail the acquisition of a total of seven intraocular pressure (IOP) measurements from each subject.\n\n* T0: Baseline (pre-intervention, resting).\n* T1: Immediately after 1 minute of forced expiration at Level 1.\n* T2: Immediately after 1 minute of forced expiration at Level 2.\n* T3: Immediately after 1 minute of forced expiration at Level 3.\n* T4: Immediately after 1 minute of forced expiration at Level 4.\n* T5: Immediately after 1 minute of forced expiration at Level 5.\n* T6: Immediately after 1 minute of forced expiration at Level 6.",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Ali Y Karahan, Prof.","University of Usak","STUDY_CHAIR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":19,"email":30},"Ata Baytaroglu, Asst. Prof.","CONTACT","+905379315396","ata.baytaroglu@usak.edu.tr",{"name":32,"role":28,"phone":29,"phoneExt":19,"email":33},"Serife N Ciftci, Asst. Prof.","ciftciserifenur@gmail.com",[35],{"facility":23,"status":36,"city":37,"state":19,"zip":38,"country":39,"countryCode":19,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Uşak","64200","Turkey (Türkiye)",{"type":41,"coordinates":42},"Point",[43,44],29.4058,38.67351,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":49,"phoneExt":19,"email":50},"Ali Y Karahan","+905386921934","ali.karahan@usak.edu.tr",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Ali Yavuz Karahan","Professor","100614021","the-effect-of-graded-forced-expiration-on-intraocular-pressure-100614021",false,"NCT07274176","The Effect of Graded Forced Expiration on Intraocular Pressure","The Effect of Graded Forced Expiration on Intraocular Pressure: A Study Using the Airofit Device","Inclusion Criteria:\n\n* Aged 18 years or older.\n* Willing and able to provide informed consent.\n* Have a best-corrected visual acuity of 6\u002F12 or better.\n* Able to understand and follow instructions for using the Airofit device.\n* Have an optic nerve cup\u002Fdisc ratio not exceeding 0.5, and have a c\u002Fd difference between both eyes not exceeding 0.2.\n* Did not have taken any anticholinergic medication, systemic beta-blockers, or corticosteroids within the last 3 months that could affect intraocular pressure levels.\n\nExclusion Criteria:\n\n* a history of intraocular surgery,\n* a history of uveitis,\n* a spherical refractive error exceeding 3D,\n* a history of regular topical treatment other than artificial tears",true,"ALL","18 Years","65 Years",{"count":67,"type":68},60,"ESTIMATED","INTERVENTIONAL",[71],"NA","The primary objective of this study is to utilize the Airofit device to systematically measure and characterize the changes in intraocular pressure across its six different levels of forced expiration. This investigation will provide crucial quantitative data on the IOP-respiratory effort relationship, enhancing our understanding of IOP dynamics during controlled respiratory stress and establishing a new, standardized paradigm for such research.",[74],"Intraocular Pressure","2025-12-15",{"date":77,"type":78},"2025-12-22","ACTUAL",{"date":75,"type":78},{"date":81,"type":68},"2026-02-25",{"name":5,"class":6},1]