[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579566":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":35,"responsibleParty":51,"collaborators":55,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":24,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":24,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":84,"whyStopped":24,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Loughborough University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Euhydrated","EXPERIMENTAL","Light exercise in a hot environment with water ingested to fully replace sweat losses and maintain euhydration.",[13],"Other: Water intake",{"label":15,"type":10,"description":16,"interventionNames":17},"Hypohydrated","Light exercise in a hot environment with water restricted to induce hypohydration of \\~3% body mass through sweating.",[18],"Other: Water restriction",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Water intake","Water ingested to fully replace sweat losses during exercise.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Water restriction","Water restriction to induce hypohydration of \\~3% body mass through sweat losses during exercise.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Lewis J James, PhD","CONTACT","+44 (0) 1509 226305","L.James@lboro.ac.uk",[36],{"facility":5,"status":24,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Loughborough","Leicestershire","LE113TU","United Kingdom","UK",{"type":43,"coordinates":44},"Point",[45,46],-1.2,52.76667,{"lat":46,"lon":45},[49],{"name":50,"role":32,"phone":33,"phoneExt":24,"email":34},"Lewis J James",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Lewis James","Dr",[56],{"name":57,"class":58},"National Institute for Health Research Leicester Biomedical Research Centre","UNKNOWN","100579566","the-effect-of-hydration-on-postprandial-metabolic-responses-100579566",false,"NCT06825962","The Effect of Hydration on Postprandial Metabolic Responses","Inclusion Criteria:\n\n* Male or female\n* Generally fit and healthy\n* Participate in endurance or intermittent exercise at least 3 times a week or minimum of 150 minutes moderate intensity activity per week\n\nExclusion Criteria:\n\n* \\\u003C 18 or \\> 45\n* Any health condition that may affect study outcomes (e.g., endocrine\u002Fliver\u002Frenal\u002Fcardiovascular disease)\n* Any morbidity that affects ability to cycle\n* Smoker or vaper",true,"ALL","18 Years","45 Years",{"count":70,"type":71},16,"ESTIMATED","INTERVENTIONAL",[74],"NA","Certain populations, such as industrial workers and endurance athletes are particularly susceptible to dehydration due to exposure to heat for long periods of time causing evaporative water loss via sweating. The physical and cognitive decrements associated with dehydration have been widely researched, however the effect of dehydration on metabolism is lesser known. As climate change is causing temperatures to rise, and metabolic diseases such as type 2 diabetes are more common, the effect of dehydration on metabolism, specifically glycemic response to meals, needs to be established for future recommendations in clinical, environmental and athletic settings.\n\nTherefore, the aim of this study is to investigate the effect of acute exercise-induced dehydration on subsequent metabolic responses to feeding (i.e. glycaemia and insulinaemia).",[77],"Glycaemia",[79,80,81,82,77,83],"Hydration","Dehydration","Hypohydration","Glycemia","Glucose control","NOT_YET_RECRUITING","2025-02-10",{"date":87,"type":88},"2025-02-13","ACTUAL",{"date":90,"type":71},"2025-03",{"date":92,"type":71},"2025-12",{"name":5,"class":6},1]