[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573985":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":25,"centralContacts":30,"locations":41,"responsibleParty":67,"collaborators":35,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":35,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":35,"enrollmentInfo":79,"targetDuration":35,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":44,"whyStopped":35,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Kutahya Health Sciences University","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Thin phenotype","Mucosa thickness is less than 1 mm and the visibility of the probe in the sulcus is high.",[12],"Procedure: Platelet rich fibrin",{"label":14,"type":6,"description":15,"interventionNames":16},"Thick phenotype","Mucosa thickness is greater than 1 mm and visibility of the probe in the sulcus is low.",[12],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"PROCEDURE","Platelet rich fibrin","The injectable platelet rich fibrin will be integrated into the tissue by subgingival and submucosal application to the keratinized gingiva of the implant sites with insufficient peri-implant soft tissue phenotype. Then, the prepared injectable platelet rich fibrin will be injected into the mucogingival junction apical to the keratinized gingival site. This procedure will be repeated 3 times in total, 1 time in 30 days for 3 months.",[14,9],[24],"Injectable plateler rich fibrin",[26],{"name":27,"affiliation":28,"role":29},"Berceste Güler Ayyıldız, Assoc. Prof. Dr","Kütahya Health Sciences University","STUDY_DIRECTOR",[31,37],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},"Berceste Güler Ayyıldız","CONTACT","+05059359207",null,"berceste.guler@ksbu.edu.tr",{"name":38,"role":33,"phone":39,"phoneExt":35,"email":40},"Seyma Eken","05518489820","seyma.eken@ksbu.edu.tr",[42],{"facility":43,"status":44,"city":45,"state":35,"zip":46,"country":47,"countryCode":35,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Kütahya Health Sciences University Faculty of Dentistry","RECRUITING","Kütahya","43100","Turkey (Türkiye)",{"type":49,"coordinates":50},"Point",[51,52],29.98333,39.42417,{"lat":52,"lon":51},[55,59,62,64],{"name":56,"role":33,"phone":57,"phoneExt":35,"email":58},"Berceste Guler Ayyıldız, Associate Professor Dr.","905059359207","berceste43@gmail.com",{"name":60,"role":61,"phone":35,"phoneExt":35,"email":35},"Seyma Eken, Lect. Dr","SUB_INVESTIGATOR",{"name":63,"role":61,"phone":35,"phoneExt":35,"email":35},"Busra Terzioglu, Lect. Dr.",{"name":65,"role":66,"phone":35,"phoneExt":35,"email":35},"Berceste Guler Ayyıldız, Assoc. Prof. Dr","PRINCIPAL_INVESTIGATOR",{"type":66,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"Berceste Guler","Associate Professor Dr.","100573985","the-effect-of-injectable-platelet-rich-fibrin-in-peri-implant-soft-tissue-100573985",false,"NCT06753396","The Effect of Injectable Platelet-Rich Fibrin in Peri-implant Soft Tissue","Evaluation of the Effect of Injectable Platelet-Rich Fibrin on Peri-Implant Soft Tissue Phenotype","Inclusion Criteria:\n\n1. be over 18 years old\n2. The patient does not have any systemic disease\n3. Patients who do not smoke or who smoke less than 10 cigarettes\n4. Peri-implant keratinized mucosa width less than 2 mm\n5. Peri-implant mucosal thickness less than 2 mm\n\nExclusion Criteria:\n\n1. Being out of the defined age group\n2. Any systematic contraindication for periodontal surgery\n3. Patients who smoke more than 10 cigarettes per day\n4. Patients with adequate peri-implant keratinized mucosa width and mucosal thickness\n5. Pregnancy\n6. Patients taking medication that suppresses the immune system or impairs healing\n7. Patients taking medication that impairs the bleeding condition","ALL","18 Years",{"count":80,"type":81},80,"ESTIMATED","INTERVENTIONAL",[84],"NA","An inadequate amount of peri-implant soft tissue results in more plaque accumulation around the implants, peri-implant mucositis, marginal bone loss, mucosal recession, and\u002For attachment loss. In the literature, there are studies evaluating the application of injectable platelet-rich fibrin to the gingiva and oral mucosa around teeth, but injectable platelet-rich fibrin application around implants has not been encountered. This study aimed to evaluate the effect of subgingival and submucosal application of injectable platelet-rich fibrin on peri-implant soft tissue phenotype in patients with inadequate peri-implant soft tissue phenotype.The study will include 80 systemically healthy and non-smoking patients\u002Fimplants older than 18 years of age with insufficient peri-implant keratinized mucosa width and mucosal thickness who applied to Kütahya University of Health Sciences, Faculty of Dentistry, Department of Periodontology. There are two study groups according to peri-implant mucosa phenotype: Thin phenotype and thick phenotype. All patients will undergo the same procedure of injectable platelet-rich fibrin application",[87],"Peri-Implant Tissues",[89,90,91,92],"Peri-implant soft tissue","Injectable platelet-rich fibrin","Platelet-rich fibrin","Phenotype","2025-09-04",{"date":95,"type":96},"2025-09-11","ACTUAL",{"date":98,"type":96},"2022-12-15",{"date":100,"type":81},"2026-04-15",{"name":5,"class":6},1]