[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639251":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":36,"collaborators":10,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":10,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":53,"studyType":54,"phases":10,"briefSummary":55,"conditions":56,"keywords":65,"overallStatus":70,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Izmir Democracy University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Group 1",null,"Knee osteoarthritis with lipedema",{"label":13,"type":10,"description":14,"interventionNames":10},"Group 2","Knee osteoarthritis without lipedema",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Kadir Songür, Assoc. Prof.","CONTACT","+905054529231","kadir.93@gmail.com",[22],{"facility":5,"status":10,"city":23,"state":24,"zip":25,"country":26,"countryCode":10,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"Izmir","İzmir","35570","Turkey (Türkiye)",{"type":28,"coordinates":29},"Point",[30,31],27.13838,38.41273,{"lat":31,"lon":30},[34],{"name":35,"role":18,"phone":19,"phoneExt":10,"email":20},"Kadir Songür",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Kadir Songur","Dr. Lecturer","100639251","the-effect-of-lipedema-on-knee-osteoarthritis-100639251",false,"NCT07575555","The Effect of Lipedema on Knee Osteoarthritis","The Effect of Lipedema on Knee Osteoarthritis: A Cross-Sectional Analysis of Clinical Symptoms and Ultrasonographic Findings","Inclusion Criteria:\n\nAll participants (Group 1 + Group 2)\n\n* Women aged 30-65\n* With a clinical and radiological diagnosis of knee osteoarthritis\n* Who agreed to participate in the study\n\nGroup 1 (knee osteoarthritis with lipedema):\n\n* Patients who meet the Wold criteria for a clinical diagnosis of lipedema\n* An increase in subcutaneous fat thickness confirmed by ultrasound\n\nGroup 2 (knee osteoarthritis without lipedema):\n\n* No diagnosis of lipedema\n* Exclusion of lymphedema and venous diseases\n\nExclusion Criteria:\n\n* Inflammatory arthritis\n* History of knee surgery\n* Intra-articular injection within the past 6 months\n* Acute trauma\n* Systemic connective tissue disease\n* Severe venous insufficiency or lymphedema\n* History of malignancy\n* Use of gabapentinoids\u002FSNRIs\u002FSSRIs due to fibromyalgia or psychiatric illness\n* Severe cognitive impairment or communication problems that would prevent participation in the study\n* Pregnancy\n* Participants who were informed about the study and refused to participate","FEMALE","30 Years","65 Years",{"count":51,"type":52},76,"ESTIMATED","1 Day","OBSERVATIONAL","This study will be one of the few to examine the effect of lipedema on knee osteoarthritis in a comparative manner with a control group within the same osteoarthritis context. Although the relationship between obesity and osteoarthritis has been extensively studied in the literature, the effect of specific adipose tissue pathologies, such as lipedema, on osteoarthritis has not been sufficiently investigated. This study aims to demonstrate the independent effect of lipedema on osteoarthritis, evaluate clinical and ultrasonographic parameters together, and contribute to early diagnosis and targeted rehabilitation strategies.",[57,58,59,60,61,62,63,64],"Lipedema","Knee Osteoarthritis","Knee Acute and Chronic Pain","Knee","Knee Arthritis Osteoarthritis","Knee Arthropathy","Knee Cartilage Defects","Knee Cartilage Lesions",[66,67,68,69],"lipedema","knee osteoarthritis","knee joint","knee","NOT_YET_RECRUITING","2026-05-03",{"date":73,"type":74},"2026-05-08","ACTUAL",{"date":76,"type":52},"2026-07-15",{"date":78,"type":52},"2027-08-15",{"name":5,"class":6},1]