[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597466":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":53,"collaborators":26,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":26,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Universitas Diponegoro","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Low Level Tragus Stimulation Group","EXPERIMENTAL","Participant will undergo low level tragus stimulation using Parasym Device",[13,14],"Device: Parasym Neuromodulation Device (Treatment Group)","Device: Parasym Neuromodulation Device (Sham Group)",{"label":16,"type":17,"description":18,"interventionNames":19},"Sham Control Group","SHAM_COMPARATOR","Participant will have Parasym Device implanted in their tragus without any active stimulation from the device",[13,14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Parasym Neuromodulation Device (Treatment Group)","Participant will undergo stimulation in their left tragus for 60 minutes by using Parasym device",[9,16],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Parasym Neuromodulation Device (Sham Group)","Participant will undergo implantation of Parasym device lead in their left tragus but without any stimulation for 60 minutes",[9,16],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Leo Deddy Pradipta","CONTACT","+6281316499074","dancingdeagle@gmail.com",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":26,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Dr. Kariadi Central General Hospital","RECRUITING","Semarang","Central of Java","Indonesia","ID",{"type":46,"coordinates":47},"Point",[48,49],110.42083,-6.99306,{"lat":49,"lon":48},[52],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Sodiqur Rifqi","Principal Investigator; Former of Head of Department of Cardiovascular Medicine Faculty of Medicine Universitas Diponegoro","100597466","the-effect-of-low-level-tragus-stimulation-on-echocardiographic-parameters-in-patients-with-st-segment-elevation-myocardial-infarction---a-single-centre-randomized-control-trial-100597466",false,"NCT07058857","The Effect of Low-Level Tragus Stimulation on Echocardiographic Parameters in Patients With ST-Segment Elevation Myocardial Infarction - A Single-Centre Randomized Control Trial","ELITE-STEMI","Inclusion Criteria:\n\n* Onset STEMI less than 12 hours\n* Participant agreed to be included in this study\n* Killip class I - II on presentation\n* SBP \\>90 mmHg and\u002For MAP \\>65 mmHg\n* Sinus rhtyhm\n\nExclusion Criteria:\n\n* History of myocardial infarction, stroke, heart failure with reduce ejection fraction, chronic total occlussion on prior coronary angiography, chronic kidney disease (eGFR \\\u003C 30) or on hemodyalisis, malignancy, hematology disease, autoimmune, or other chronic diseases\n* On permanent pacemaker\n* Acute infection\n* Pregnant woman","ALL","18 Years","75 Years",{"count":68,"type":69},100,"ESTIMATED","INTERVENTIONAL",[72],"NA","The goal of this clinical trial is to learn the effect of low level tragus stimulation (LLTS) on echocardiographic parameter in patient with ST-segment Elevation Myocardial Infarction (STEMI) who undergo primart percutaneous coronary intervention (PPCI). It will also learn about the safety of LLTS in such setting. The main questions, it aims to answer are compared with sham control:\n\nDoes LLTS could alter left ventricular ejection fraction in patients with STEMI? Does LLTS could alter wall motion score index in patients with STEMI? Does LLTS could alter diastolic dysfunction in patients with STEMI?\n\nResearchers will compare LLTS to sham LLTS control to see if LLTS have benefit in participants with STEMI participants will divided into two group i.e. treatment group vs control (sham\u002Fplacebo) group..\n\nBoth groups undergo transthoracal echocardiographi examination before and after PPCI..",[75],"ST Elevation Myocardial Infarction",[77,78,79,80],"ST-segment elevation myocardial infarction","Low level tragus stimulation","Left ventricular ejection fraction","Wall motion score index","2025-06-30",{"date":83,"type":84},"2025-07-10","ACTUAL",{"date":86,"type":84},"2025-01-01",{"date":88,"type":69},"2025-09-30",{"name":5,"class":6},1]