[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599231":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":44,"locations":50,"responsibleParty":65,"collaborators":69,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":28,"eligibilityCriteria":87,"healthyVolunteers":83,"sex":88,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":28,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":28,"overallStatus":53,"whyStopped":28,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Guang'anmen Hospital of China Academy of Chinese Medical Sciences","OTHER",[8,17],{"label":9,"type":10,"description":11,"interventionNames":12},"TEAS + TCM + Prehabilitation + ERAS","EXPERIMENTAL","Experimental Group:\n\nTEAS:\n\nAdministered once daily from the day of surgery until postoperative day 4. Each session lasts 30 minutes, except on the day of surgery, when treatment begins 30 minutes preoperatively and continues for 1 hour.\n\nAcupoints: ST36 (Zusanli), ST37 (Shangjuxu), PC6 (Neiguan), and LI4 (Hegu) Note: Intraoperatively, only bilateral ST36 and ST37 are stimulated due to anesthesia constraints.\n\nParameters: Continuous wave at 10 Hz; intensity adjusted to elicit deqi sensation (heaviness, numbness, or soreness) within patient tolerance.\n\nTraditional Chinese Medicine (TCM):\n\nIntraoperative \\& Postoperative (up to day 4): Fixed prescription of Da Jian Zhong Tang Zanthoxyli Pericarpium (Sichuan Pepper) 3g, Zingiberis Rhizoma (Dried Ginger) 12g, Ginseng Radix et Rhizoma (Ginseng) 6g, Maltosum (Malt Sugar) 30g.\n\nAll participants receive identical perioperative management and postoperative care, including prehabilitation and Enhanced Recovery After Surgery (ERAS) protocols.",[13,14,15,16],"Drug: Da Jian Zhong Tang (Zanthoxylum, Ginger, Ginseng, Maltose)","Procedure: Transcutaneous Electrical Acupoint Stimulation (TEAS)","Other: ERAS","Other: Multimodal Prehabilitation Program",{"label":18,"type":19,"description":20,"interventionNames":21},"Prehabilitation + ERAS","ACTIVE_COMPARATOR","All participants receive identical perioperative management and postoperative care, including prehabilitation and Enhanced Recovery After Surgery (ERAS) protocols.",[15,16],[23,29,34,40],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DRUG","Da Jian Zhong Tang (Zanthoxylum, Ginger, Ginseng, Maltose)","\"Da Jian Zhong Tang (Zanthoxylum, Ginger, Ginseng, Maltose)was administered orally twice daily from preoperative day 3 to postoperative day 3. The decoction aims to warm the middle jiao and promote gastrointestinal recovery, with dose adjustments based on syndrome differentiation.",[9],null,{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":28},"PROCEDURE","Transcutaneous Electrical Acupoint Stimulation (TEAS)","TEAS was delivered at acupoints ST36\u002FST37 (10Hz continuous wave, 30min\u002Fsession) once daily from intraoperative day to postoperative day 4. On surgery day, stimulation started 30min preoperatively for 1 hour. Intensity was adjusted to elicit deqi sensation.",[9],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":38},"ERAS","\"Standardized ERAS protocol included: (1) Preoperative carbohydrate loading; (2) Intraoperative goal-directed fluid therapy; (3) Minimally invasive surgery; (4) Multimodal opioid-sparing analgesia; (5) Early oral feeding (semi-liquid diet at 6h post-op); (6) Early ambulation (first mobilization at 8h post-op). Implemented by a multidisciplinary team.",[18,9],[39],"Fast-Track Surgery",{"type":6,"name":41,"description":42,"armGroupLabels":43,"otherNames":28},"Multimodal Prehabilitation Program","(1) Exercise: Daily aerobic\u002Fresistance training (30min, 5×\u002Fweek); (2) Nutrition: High-protein diet (1.5g\u002Fkg\u002Fday) + oral supplements if needed; (3) Psychological Support: Cognitive-behavioral therapy sessions (2×\u002Fweek). Tailored to individual patient risk profiles.",[18,9],[45],{"name":46,"role":47,"phone":48,"phoneExt":28,"email":49},"Quanda Liu Liu","CONTACT","+8688001037","15549437482@163.com",[51],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":28},"Guang'anmen Hospital China Academy of Chinese Medical Sciences","RECRUITING","Beijing","Beijing Municipality","100053","China","CN",{"type":60,"coordinates":61},"Point",[62,63],116.39723,39.9075,{"lat":63,"lon":62},{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"PRINCIPAL_INVESTIGATOR","Quanda Liu","Chief Physician",[70,72,75,77,79],{"name":71,"class":6},"Second Affiliated Hospital of Nanchang University",{"name":73,"class":74},"The First Hospital of Qinhuangdao","OTHER_GOV",{"name":76,"class":6},"Affiliated Hospital of Hebei University",{"name":78,"class":6},"Handan Central Hospital",{"name":80,"class":6},"Liaoning Cancer Hospital & Institute","100599231","the-effect-of-perioperative-transcutaneous-electrical-acupoint-stimulation-combined-with-traditional-chinese-medicine-on-gastrointestinal-function-recovery-in-patients-undergoing-abdominal-surgery-100599231",false,"NCT07081802","The Effect of Perioperative Transcutaneous Electrical Acupoint Stimulation Combined With Traditional Chinese Medicine on Gastrointestinal Function Recovery in Patients Undergoing Abdominal Surgery","the Effect of Perioperative Transcutaneous Electrical Acupoint Stimulation Combined With Traditional Chinese Medicine on Gastrointestinal Function Recovery in Abdominal Surgery Patients","Inclusion Criteria:\n\n* Patients aged \\>18 years with no severe preoperative gastrointestinal dysfunction (e.g., no chronic gastrointestinal diseases such as long-term constipation or diarrhea).\n* Scheduled abdominal Grade IV surgeries (limited to liver, gallbladder, pancreas, stomach, or intestinal procedures) performed via open or laparoscopic approach.\n* Preoperative American Society of Anesthesiologists (ASA) Physical Status Classification of I-III.\n* Patients and their families fully understand the study's purpose, methods, potential risks\u002Fbenefits, and provide signed informed consent.\n\nExclusion Criteria:\n\n* Comorbid severe systemic diseases.\n* Local skin abnormalities at acupoints (e.g.,broken skin, infection, allergies, or scarring).\n* Preoperative long-term use (\\>1 month) of gastrointestinal motility-affecting drugs (e.g., mosapride, domperidone) that cannot be discontinued, or allergies to TCM components\u002Felectrode materials.\n* Psychiatric disorders or cognitive impairment rendering patients unable to comply with the study.\n\nElimination Criteria:\n\n* Non-compliance with treatment protocols (e.g., receiving \\\u003C80% of planned sessions).\n* Significant missing data.\n* Occurrence of severe adverse events unrelated to the study intervention.","ALL","18 Years","80 Years",{"count":92,"type":93},148,"ESTIMATED","INTERVENTIONAL",[96],"NA","Protocol Summary Project Name:Effect of Perioperative TEAS Combined with TCM on Gastrointestinal Function Recovery in Abdominal Surgery Patients Research Objective:To evaluate the impact of perioperative TEAS combined with TCM on postoperative gastrointestinal function, pain, adverse reactions, hospital stay, and complications, as well as its safety, aiming to enrich the ERAS and prehabilitation theory and promote the integration of TCM in surgical practice.\n\nResearch Design:Prospective, randomized, open-label trial involving 148 abdominal surgery patients (Grade IV surgeries) randomly assigned 1:1 to the experimental group (TCM + TEAS + prehabilitation + ERAS) or the control group (prehabilitation + ERAS).\n\nTotal Cases:148 Case Selection\n\nInclusion Criteria:\n\n1. Age 18-80, no severe gastrointestinal dysfunction;\n2. Elective abdominal Grade IV surgeries (pancreas or colorectall surgeries) via open or laparoscopic methods;\n3. Preoperative ASA classification I-III;\n4. Signed informed consent.\n\nExclusion Criteria:\n\nSevere comorbidities, skin abnormalities at acupoints, long-term use of gastrointestinal motility drugs, or other factors affecting the trial.\n\nElimination Criteria:\n\nPoor compliance, significant missing data, or severe adverse events unrelated to the intervention.\n\nTreatment Plan TEAS combined with TCM from the day of surgery to postoperative day 4, alongside prehabilitation and ERAS.\n\nEfficacy Evaluation\n\nPrimary Outcomes:\n\nTime to first flatus and defecation.\n\nSecondary Outcomes:\n\nPostoperative hospital stay, time to tolerate semi-liquid\u002Fsolid food, nausea\u002Fvomiting, pain, bloating, first ambulation, 30-day readmission rate, WBC\u002FCRP levels, and gastrin levels.\n\nSafety Evaluation: Any adverse events. Statistical Methods Continuous variables expressed as mean (SD) or median (IQR); independent t-test for normal distributions. Categorical variables summarized as frequencies\u002Fpercentages, analyzed using χ² or Fisher's exact test. Group differences reported as 95% CI and two-sided P-values (P \\\u003C 0.05 significant). Preset subgroup analyses by surgery type and frailty.",[35,99],"Traditional Chinese Medication (TCM)","2026-05-30",{"date":102,"type":103},"2026-06-02","ACTUAL",{"date":105,"type":103},"2025-09-01",{"date":107,"type":93},"2026-09-28",{"name":5,"class":6},1]