[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619950":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":26,"locations":32,"responsibleParty":52,"collaborators":18,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":18,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":18,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":18,"overallStatus":76,"whyStopped":18,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"University of Health Sciences Lahore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Case Group","EXPERIMENTAL","PRF placement in extraction socket",[13],"Other: Platelet rich fibrin",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","NO_INTERVENTION","Surgical extraction without using PRF",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Platelet rich fibrin","After surgical extraction of impacted mandibular 3rd molar PRF will be placed in extraction socket",[9],[25],"PRF",[27],{"name":28,"role":29,"phone":30,"phoneExt":18,"email":31},"MHayat","CONTACT","+923420690087","uhayat722@gmail.com",[33],{"facility":34,"status":18,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Allama Iqbal Medical College\u002F Jinnah Hospital","Lahore","Punjab Province","54000","Pakistan","PK",{"type":41,"coordinates":42},"Point",[43,44],74.35071,31.558,{"lat":44,"lon":43},[47],{"name":48,"role":29,"phone":49,"phoneExt":50,"email":51},"Allama Iqbal Medical College (AIMC)","+92-42-99231480","+92-42-9923144","Info@aimc.edu.pk",{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Muhammad Umar Hayat","PGR OMFS( MDS)","100619950","the-effect-of-platelet-rich-fibrin-on-sensitivity-and-periodontal-pockets-distal-to-second-molar-after-surgical-extraction-of-impacted-third-molar-100619950",false,"NCT07351279","The Effect of Platelet Rich Fibrin On Sensitivity and Periodontal Pockets Distal to Second Molar After Surgical Extraction of Impacted Third Molar","\" The Effect of Platelet Rich Fibrin On Sensitivity and Periodontal Pockets Distal to Second Molar After Surgical Extraction of Impacted Third Molar \"","Inclusion Criteria:\n\n* Impacted third molar (as per Operational Definition) with fully erupted second molars bilaterally.\n* Impacted Third molar with Class 2 and Level B according to Pell and Gregory's classification (Annexure B) with mesioangular or horizontal angulation of impaction\n* Periodontal pocket depth \\> 4mm and Clinical attachment loss \\> 1mm at distal side of second molar\n* Age 18-40 years, both genders.\n* Patients who give informed consent.\n\nExclusion Criteria:\n\n* Any Systemic Disease i.e. Uncontrolled Diabetes mellitus, Uncontrolled hypertension, Ischemic heart disease, bleeding disorders, Autoimmune diseases or immunocompromised patients\n* Decayed or recommended for extraction second molars on either side.\n* Allergic to Amoxicillin to standardize Antibiotic therapy protocol.\n* Untreated periodontal condition.\n* Inability to follow up.","ALL","18 Years","40 Years",{"count":67,"type":68},56,"ESTIMATED","INTERVENTIONAL",[71],"NA","Surgical extraction of impacted third molar is the most common surgical procedure performed in oral and maxillofacial surgery. The immediate post operative complications after 3rd molar surgery are pain, swelling and trismus while delayed post operative complications are mostly seen on the distal surface of second molar due to distal bone loss which include prolonged sensitivity due to increased periodontal pocket depth, gingival recession and root exposure.\n\nWhen PRF clot is given in wound, it causes alterations of the cellular ratios in the wound blood clot, leading to replacement of blood cells with Platelets and growth factors stimulating all phases of healing which will improve the immidiate and delayed post operative complications The purpose of present study is to compare the clinical outcomes in the treatment of senstivity and periodontal pockets at the distal aspect of second molar following surgical extraction of impacted third molar using PRF or Blood clot alone.",[74,75],"Third Molar Impaction","Surgical Extraction of Impacted Third Molars","NOT_YET_RECRUITING","2026-01-11",{"date":79,"type":80},"2026-01-20","ACTUAL",{"date":82,"type":68},"2026-02",{"date":84,"type":68},"2028-02",{"name":5,"class":6},1]