[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613940":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":23,"locations":29,"responsibleParty":45,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"University of Milan","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Case group (subjects with TMD)",null,"This group contains subjects with temporomandibular disorders",[13],"Other: Mastication of sugar-free chewing gum",{"label":15,"type":10,"description":16,"interventionNames":17},"Control group (TMD-free subjects)","This group contains healthy subjects without temporomandibular disorders",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Mastication of sugar-free chewing gum","The chewing task will last for a maximum of 18 minutes.",[9,15],[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Aesha Allam, DDS","CONTACT","+39 3276218958","aesha.allam@unimi.it",[30],{"facility":5,"status":31,"city":32,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Milan","20142","Italy","IT",{"type":37,"coordinates":38},"Point",[39,40],9.18951,45.46427,{"lat":40,"lon":39},[43],{"name":44,"role":26,"phone":27,"phoneExt":10,"email":28},"Aesha Allam DDS",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Aesha Allam","DDS, Doctor, principal investigator","100613940","the-effect-of-prolonged-sugar-free-chewing-gum-mastication-on-self-reported-fatigue-levels-and-changes-of-static-and-dynamic-surface-electromyography-parameters-in-young-individuals-with-and-without-temporomandibular-joint-disorders-100613940",false,"NCT07273123","The Effect of Prolonged Sugar-Free Chewing Gum Mastication on Self-Reported Fatigue Levels and Changes of Static and Dynamic Surface Electromyography Parameters in Young Individuals With and Without Temporomandibular Joint Disorders.","Effect of Sugar-Free Chewing Gum Mastication on Fatigue of the Masticatory Muscles in Young Adults With and Without Temporomandibular Joint Disorders","Inclusion criteria (both groups):\n\n* Age 19-35 years\n* Chewing-gum users, even occasional\n* Good general health\n* Good oral health\n\nInclusion criteria (Healthy controls):\n\n\\- no diagnosed temporomandibular joint disorders\n\nInclusion criteria (study group)\n\n\\- diagnosed temporomandibular joint disorders\n\nExclusion criteria (both groups):\n\n* Non chewing gum users\n* History of neurological disorders\n* History of musculoskeletal diseases\n* History of facial or cervical injuries\n* Presence of cervical pain\n* Two or more missing teeth\n* Current treatment with fixed or removable orthodontic appliances\n* Active periodontal disease\n* Presence of cavitated carious lesions",true,"ALL","19 Years","35 Years",{"count":61,"type":62},30,"ESTIMATED","OBSERVATIONAL","This case-control study investigates fatigue induced by prolonged gum mastication in individuals with temporomandibular disorders (TMD). The study addresses two primary questions:\n\nHow does self-reported fatigue, measured with a visual analogue scale (VAS), change during sustained chewing? How do static and dynamic surface electromyographic (sEMG) parameters evolve over the same period? Participants with TMD will be compared with healthy controls to determine group differences in perceived fatigue and EMG responses.\n\nAll participants will undergo baseline EMG assessment, then chew sugar-free gum continuously for 3 minutes, alternating sides without rest. After each 3-minute interval, static and dynamic EMG recordings will be obtained and participants will rate their fatigue on the VAS. This cycle may be repeated up to six times (maximum 18 minutes). Participants are free to stop chewing at any time if fatigue becomes intolerable.",[66],"Temporomandibular Joint Disorder","2026-04-27",{"date":69,"type":70},"2026-05-01","ACTUAL",{"date":72,"type":70},"2025-10-01",{"date":74,"type":62},"2026-07-30",{"name":5,"class":6},1]