[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100564847":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":67,"collaborators":71,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":24,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":24,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Beijing Normal University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"real rTMS on the dlPFC","EXPERIMENTAL","rTMS on the DLPFC Dorsolateral prefrontal cortex (DLPFC) target will be identified by the baseline functional magnetic resonance imaging (fMRI) study for regulation of craving using a separate sample. During the intervention, each participant will receive an iTBS mode intervention on this DLPFC region.",[13],"Other: real rTMS on the dlPFC",{"label":15,"type":16,"description":17,"interventionNames":18},"sham rTMS on the dlPFC","SHAM_COMPARATOR","Each participant will also receive a sham rTMS intervention as a controlled condition.",[19],"Other: Sham (No Treatment)",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"During real rTM session, participants will perform the regulation of craving (ROC). In the rest phase, participants need to relax and rest. In the ROC task, participants will regulate craving elicited by gaming pictures using cognitive reappraisal. During the task, reaction times (RTs) and craving scores wil be recorded.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Sham (No Treatment)","During the sham rTMS session, participants will perform the regulation of craving (ROC). In the ROC task, participants will regulate craving elicited by gaming pictures using cognitive reappraisal. During the task, reaction times (RTs) and craving scores wil be recorded.",[15],[30],{"name":31,"affiliation":5,"role":32},"Jin-Tao Zhang, Phd","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":24,"email":37},"CONTACT","15010233046","zhangjintao@bnu.edu.cn",[39,57],{"facility":40,"status":41,"city":42,"state":43,"zip":24,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Medical Ethics Committee of Zhenjiang Mental Health Center","RECRUITING","Zhenjiang","Jiangsu","China","CN",{"type":47,"coordinates":48},"Point",[49,50],119.45508,32.21086,{"lat":50,"lon":49},[53],{"name":54,"role":35,"phone":55,"phoneExt":24,"email":56},"Zi-Liang Wang, Phd","18395949625","wangziliang201@163.com",{"facility":58,"status":41,"city":59,"state":24,"zip":24,"country":44,"countryCode":45,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"State Key Laboratory of Cognitive Neuroscience and Learning","Beijing",{"type":47,"coordinates":61},[62,63],116.39723,39.9075,{"lat":63,"lon":62},[66],{"name":31,"role":35,"phone":24,"phoneExt":24,"email":37},{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","Jin-tao Zhang","Professor",[72],{"name":73,"class":74},"Zi-Liang Wang, Medical Ethics Committee of Zhenjiang Mental Health Center","UNKNOWN","100564847","the-effect-of-repetitive-transcranial-magnetic-stimulation-for-internet-gaming-disorder-100564847",false,"NCT06634498","The Effect of Repetitive Transcranial Magnetic Stimulation for Internet Gaming Disorder","The Effect of Repetitive Transcranial Magnetic Stimulation of the Left Dorsolateral Prefrontal Cortex in Internet Gaming Disorder","Inclusion Criteria:\n\n* DSM-V gaming disorder \\>5 and scored ≥ 50 on a revised version of Young's online Internet addiction test；\n* spent more than 50% of their online time gaming；\n* engagement in one of four popular Internet game (Arena of Valor,Genshine, LOL, FPS) for over 20 hours per week for at least 1 year.\n\nExclusion Criteria:\n\n* current or history of use of illegal substances and gambling;\n* current or history of psychiatric or neurological illness;\n* current use of psychotropic medications;\n* cognitive impairment as assessed by the Mini-International Neuropsychiatric Interview；\n* surgery, head trauma or heart related diseases in the past year；\n* a history of epilepsy or seizures or increased risk of seizures for any reason；\n* metal implants or tattoos of the neck or head；\n* claustrophobia.",true,"ALL","18 Years","30 Years",{"count":87,"type":88},35,"ESTIMATED","INTERVENTIONAL",[91],"NA","This study aims to investigate the intervention effects of navigated repetitive transcranial magnetic stimulation (rTMS) on craving regulation in individuals with internet gaming disorder (IGD). The primary objectives include: (1) examining the impact of navigated rTMS over the dorsolateral prefrontal cortex (DLPFC) on the gaming cravings, and craving regulation capacity; and (2) exploring the potential neural mechanisms by which rTMS over the DLPFC improves craving intensity, and craving regulation ability.",[94],"Internet Gaming Disorder",[96,97,98,99],"rTMS","Internet gaming disorder","craving","craving regulation","2024-10-09",{"date":102,"type":103},"2024-10-15","ACTUAL",{"date":105,"type":88},"2024-10-10",{"date":107,"type":88},"2025-06-30",{"name":69,"class":6},2]