[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100533775":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":40,"responsibleParty":110,"collaborators":25,"id":112,"slug":113,"hasResults":114,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":120,"sex":121,"minAge":122,"maxAge":123,"enrollmentInfo":124,"targetDuration":25,"studyType":127,"phases":128,"briefSummary":130,"conditions":131,"keywords":25,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":142},{"fullName":5,"class":6},"Population Health Research Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Retrograde autologous priming","EXPERIMENTAL","sites implement retrograde autologous priming (RAP) during cardiac surgery",[13],"Procedure: retrograde autologous priming (RAP)",{"label":15,"type":10,"description":16,"interventionNames":17},"Crystalloid priming","sites implement crystalloid priming use during cardiac surgery",[18],"Procedure: Crystalloid priming",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","retrograde autologous priming (RAP)","sites follow an institutional policy of routine use of retrograde autologous priming (RAP) during cardiac surgery",[9],null,{"type":21,"name":15,"description":16,"armGroupLabels":27,"otherNames":25},[15],[29],{"name":30,"affiliation":5,"role":31},"Jessica Spence, MD, PhD","PRINCIPAL_INVESTIGATOR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":25,"email":37},"TheRAPy Study Coordinator","CONTACT","9055212100","therapy@phri.ca",{"name":39,"role":35,"phone":25,"phoneExt":25,"email":25},"Jessica Spence",[41,65,82,96],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"St. Boniface Hospital","RECRUITING","Winnipeg","Manitoba","R2H 2A6","Canada","CA",{"type":50,"coordinates":51},"Point",[52,53],-97.14704,49.8844,{"lat":53,"lon":52},[56,60,63],{"name":57,"role":35,"phone":58,"phoneExt":25,"email":59},"Dayna Solvason","1 (204) 430-9815","dsolvason@sharedhealthmb.ca",{"name":61,"role":35,"phone":58,"phoneExt":25,"email":62},"Angela Recio","Angela.Recio@umanitoba.ca",{"name":64,"role":31,"phone":25,"phoneExt":25,"email":25},"Mullein Thorliefson, Dr.",{"facility":66,"status":43,"city":67,"state":68,"zip":69,"country":47,"countryCode":48,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Hamilton General Hospital","Hamilton","Ontario","L8S 48L",{"type":50,"coordinates":71},[72,73],-79.84963,43.25011,{"lat":73,"lon":72},[76,80],{"name":77,"role":35,"phone":78,"phoneExt":25,"email":79},"Courtney Mullen","905-521-2100","Courtney.Mullen@phri.ca",{"name":81,"role":31,"phone":25,"phoneExt":25,"email":25},"Emilie Belley-Cote, Dr",{"facility":83,"status":43,"city":84,"state":85,"zip":86,"country":47,"countryCode":48,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Montreal Heart Institute","Montreal","Quebec","H1T 1C8",{"type":50,"coordinates":88},[89,90],-73.58781,45.50884,{"lat":90,"lon":89},[93],{"name":94,"role":35,"phone":25,"phoneExt":25,"email":95},"Alain Deschamps, Dr","a.deschamps@umontreal.ca",{"facility":97,"status":43,"city":84,"state":85,"zip":98,"country":47,"countryCode":48,"cosmosGeoPoint":99,"geoPoint":101,"contacts":102},"Centre Hospitalier de l'Université de Montréal (CHUM)","H2X 0A9",{"type":50,"coordinates":100},[89,90],{"lat":90,"lon":89},[103,108],{"name":104,"role":35,"phone":105,"phoneExt":106,"email":107},"Julie Desroches, PhD","514 890-8000","12172","julie.desroches.chum@ssss.gouv.qc.ca",{"name":109,"role":31,"phone":25,"phoneExt":25,"email":25},"Francois Martin Carrier, Dr.",{"type":111,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100533775","the-effect-of-retrograde-autologous-priming-on-transfusion-requirements-after-cardiac-surgery-100533775",false,"NCT06230198","The Effect of Retrograde Autologous Priming on Transfusion Requirements After Cardiac Surgery","The Effect of Retrograde Autologous Priming on Transfusion Requirements After Cardiac Surgery (TheRAPy): a Multiple Period Vanguard Cluster Crossover Trial","TheRAPy","Inclusion Criteria:\n\n* Hospitals completing \\>200 adult cardiac surgical cases a year; (ii) 95% of cardiovascular surgery group (i.e., cardiac anesthesiologists, surgeons, and perfusionists) agree to manage patients under both autologous priming policies as per their randomization schedule for the duration of the trial.\n* All patients undergoing cardiac surgery on cardiopulmonary bypass at an enrolled site during the trial period will be included in data collection.\n\nExclusion Criteria:\n\n* Complete \\\u003C=200 cardiac surgical cases.\n* \\\u003C95% of their cardiovascular surgery group agrees to manage patients according to either of the two policies.",true,"ALL","10 Years","110 Years",{"count":125,"type":126},4500,"ESTIMATED","INTERVENTIONAL",[129],"NA","The TheRAPy vanguard trial is a multicentre, multiple period randomized, cluster crossover vanguard trial testing the feasibility of a full-scale trial to evaluate whether a centre-based policy of routine use of RAP versus a policy of crystalloid priming reduces RBC transfusion for patients undergoing cardiac surgery on cardiopulmonary bypass. It will also provide information about key parameters of the TheRAPy full-scale trial.",[132],"Red Blood Cell Transfusion","2025-02-27",{"date":135,"type":136},"2025-03-04","ACTUAL",{"date":138,"type":136},"2024-12-04",{"date":140,"type":126},"2026-11",{"name":5,"class":6},4]