[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565645":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":34,"responsibleParty":46,"collaborators":19,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":19,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":73,"whyStopped":19,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"University of Copenhagen","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cardiac magnetic resonance measurements","EXPERIMENTAL","Healthy participants will undergo a three and half-hour experimental day including repeated measurements of cardiac magnetic resonance and blood sampling.",[13],"Other: Bedrest",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Bedrest","Investigation of the effect of short-term bed rest (3 hours) on heart function, measured by cardiac magnetic resonance, in healthy participants ( males and females)",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Bente Kiens, D.sci, PhD","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Bente Kiens, D Sci, PhD","CONTACT","+4528751619","bkiens@nexs.ku.dk",{"name":31,"role":27,"phone":32,"phoneExt":19,"email":33},"Andreas M Fritzen, PhD","+4542633359","amfritzen@sund.ku.dk",[35],{"facility":5,"status":19,"city":36,"state":19,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":19},"Copenhagen","2100","Denmark","DK",{"type":41,"coordinates":42},"Point",[43,44],12.56553,55.67594,{"lat":44,"lon":43},{"type":23,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Bente Kiens","Professor","100565645","the-effect-of-short-term-bed-rest-on-cardiac-function-measured-by-cardiac-magnetic-resonance-imaging-100565645",false,"NCT06644872","The Effect of Short-term Bed Rest on Cardiac Function Measured by Cardiac Magnetic Resonance Imaging","MRtime","Inclusion Criteria:\n\nMale or female.\n\n* Age between 18-80 years old.\n* No use of medications with influence on heart function.\n* For ethical reasons, we only include participants who are willing to be informed on new health information, as CMR may reveal relevant secondary health findings.\n\nExclusion Criteria:\n\n* Diabetes, kidney, or liver disease.\n* Contraindications to CMR, e.g., abdominal height exceed limitations of the MR-scanner, pacemaker, aortastent, neurostimulator, or other electronic device implanted, implanted metal devices, severe claustrophobia, or physiological diseases.\n* Pregnant, lactating, or planning to become pregnant within the study period.\n* In ongoing cancer treatment.\n* Blood donation during and \\\u003C 1 month prior to study.\n* Simultaneous participation in other clinical trials potentially affecting the study outcome.\n* Inability, physically or mentally, to comply with the procedure required by the study protocol ad evaluated by the primary investigator, study manager or clinical responsible.",true,"ALL","18 Years","80 Years",{"count":61,"type":62},19,"ESTIMATED","INTERVENTIONAL",[65],"NA","The primary objective of this study is to investigate the effect of short-term bed rest (4 hours) on heart function, measured by cardiac magnetic resonance (CMR), in healthy participants. This aim will be addressed through a single-arm repeated study, assessing participants during three hours of bedrest.\n\nThe hypothesis is that short-term bed rest will decrease cardiac output measured by repeated CMR scans.\n\nThis study will also investigate the reproducibility of CMR within a narrow time frame. Limited data are available on these aspects, despite their critical importance for conducting consecutive examinations, both in clinical practice and research trials10-12. The study also aims to investigate the appliances of short-time measures of cardiac function.",[68,69],"Rest","Healthy",[71,72,69],"Cardiac output","bedrest","NOT_YET_RECRUITING","2024-10-14",{"date":76,"type":77},"2024-10-16","ACTUAL",{"date":79,"type":62},"2024-10-15",{"date":81,"type":62},"2029-01-01",{"name":5,"class":6},1]