[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100481492":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":44,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":67,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Osijek University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Blepharoplasty group",null,"As a single arm study, all examinees will undergo upper blepharoplasty. Data regarding corneal topography, tear film quality and contrast sensitivity will be obtained before the surgery, seven days and one month postoperatively",[13],"Procedure: Upper blepharoplasty",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Upper blepharoplasty","Upper eyelid surgery in local anesthesia performed by removing excess skin folds and closing with sutures placed on the skin crease.",[9],[21],{"name":22,"affiliation":5,"role":23},"Dunja Bajtl","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","+385981644381","dunjaklepo@gmail.com",[30],{"facility":5,"status":31,"city":32,"state":10,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Osijek","31000","Croatia","HR",{"type":37,"coordinates":38},"Point",[39,40],18.6942,45.55066,{"lat":40,"lon":39},[43],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":10},{"type":23,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Dunja Klepo","Principal investigator","100481492","the-effect-of-upper-blepharoplasty-on-vision-quality-in-the-early-postoperative-period-100481492",false,"NCT05549713","The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative Period","The Effect of Upper Blepharoplasty on Anatomical and Functional Aspects of Vision in the Early Postoperative Period","Inclusion Criteria:\n\n* Patients with functional dermatochalasis on the upper eyelid with subjective difficulties due to obstructing the upper part of visual field: swelling of the eyelids in the morning with difficulties in opening the eyes, use of the frontal musculature to be able to have at least a partial width of the field of vision in the upper part that is adequate for daily functioning, and headaches.\n\nExclusion Criteria:\n\n* History of corneal refractive surgery, pterygium, glaucoma, nuclear sclerosis \\> 4th degree, severe dry eye, age-related macular degeneration, neuro-ophthalmological diseases, use of hormone therapy, diabetic retinopathy or condition after panretinal photocoagulation. Corneal pathologies such as keratoconus and gross eyelid malposition conditions such as entropion, ectropion and marked laxity of the eyelids are also grounds for exclusion from the study.","ALL","45 Years","90 Years",{"count":58,"type":59},40,"ESTIMATED","OBSERVATIONAL","Contrast sensitivity (CS) and tear film (TF) changes are noted in late postoperative period after upper blepharoplasty (UB), while the same was rarely investigated in the early postoperative period. The reason for aforementioned improvement of vision quality is unclear. Suggested explanations include changes in higher-order aberrations, elimination of the overlay effect created by excess skin on the upper eyelids and\u002For eyelashes directed toward the eyelid, or changes in corneal topography (CT) and keratometry.\n\nFurthermore, there is no consensus on the best technique for UB. Due not only to different surgical techniques, but also to different methods of measuring the tear film quality, it is very difficult to quantify the aforementioned studies.\n\nWhile changes in tear volume parameters and changes in tear film (TF) rupture have been investigated in detail, changes in the lipid layer have rarely been investigated.\n\nAccording to previous studies, there are different findings about changes in CT after UB.\n\nThe aim of the research is to determine whether there are anatomical (CT) and functional (TF and CS) changes in subjects with functional dermatochalasis before the procedure and in a month-long postoperative period.\n\nThe research is conducted on examinees diagnosed by clinical examination with functional dermatochalasis with the exclusion of examinees with ocular or systemic conditions affecting TF, best corrected visual acuity or CT.\n\nDetailed medical history and ophthalmologic examination will be performed with grading of the external appearance of the upper eyelids. All diseases and conditions that can lead to changes in CS, TF or corneal defects will be noted. Preoperatively all subjects will have CS recorded in photopic conditions, TF analysis and CT (Keratograph 5M, OCULUS Optikgeraete GmbH, Wetzlar, Germany). UB will be performed in the operating room at the UED. At first (seven days postoperatively) and second (one month postoperative) check-up a CS check will be performed at the UED and TF analysis and CT at Lens LTD.",[63,64,65,66],"Excess Skin of Both Eyelids","Contrast Sensitivity","Tear Film Insufficiency of Both Eyes","Corneal Topography",[68,69,70,71,72],"Corneal topography","Contrast sensitivity","Eyelid disease","Meibomian gland dysfunction","Blepharoplasty","2024-12-30",{"date":75,"type":76},"2024-12-31","ACTUAL",{"date":78,"type":76},"2022-09-08",{"date":80,"type":59},"2026-01-01",{"name":5,"class":6},1]