[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599777":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":30,"responsibleParty":48,"collaborators":25,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":25,"eligibilityCriteria":57,"healthyVolunteers":54,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":25,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":33,"whyStopped":25,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group","ACTIVE_COMPARATOR","Patients will receive a single-shot caudal block with 1 mL\u002Fkg of 0.25% bupivacaine mixed with 1 mL of normal saline.",[13],"Procedure: caudal block with bupivacaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Experimental Group","EXPERIMENTAL","Patients will receive a single-shot caudal block with 1 mL\u002Fkg of 0.25% bupivacaine mixed with 1 µg\u002Fkg of dexmedetomidine (diluted in 1 mL of normal saline).",[19],"Procedure: caudal block using dexmedetomidine with bupivacaine",[21,26],{"type":22,"name":23,"description":17,"armGroupLabels":24,"otherNames":25},"PROCEDURE","caudal block using dexmedetomidine with bupivacaine",[15],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"caudal block with bupivacaine","Patients will receive a single-shot caudal block with 1 mL\u002Fkg of 0.25% bupivacaine mixed with 1 mL of normal saline",[9],[31],{"facility":32,"status":33,"city":34,"state":25,"zip":25,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Ain Shams university hospitals","RECRUITING","Cairo","Egypt","EG",{"type":38,"coordinates":39},"Point",[40,41],31.24967,30.06263,{"lat":41,"lon":40},[44],{"name":45,"role":46,"phone":47,"phoneExt":25,"email":47},"Dr fathy Tash","CONTACT","REC-FMASU@med.asu.eg",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Mohamed Tarek Hussein","doctor","100599777","the-effectiveness-of-dexmedetomidine-as-an-adjuvant-for-bupivacaine-caudal-block-in-pediatric-open-appendectomy-under-general-anesthesia-100599777",false,"NCT07088900","The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia","inclusion criteria:\n\n* ASA (American Society of Anesthesiologists) physical status I or II.\n* Legal guardian provides written informed consent. Exclusion Criteria\n* Refusal of participation by the legal guardian.\n* Known allergy or hypersensitivity to local anesthetics or dexmedetomidine.\n* Coagulation disorder or receiving anticoagulant therapy.\n* Active infection at or near the injection site.\n* Significant anatomical abnormalities of the lumbosacral spine.\n* Pre-existing neurological disorders, psychiatric disorders, or a history of convulsions.\n* Anticipated surgery time of more than 2.5 hours.\n* Patients with severe asthma or active wheezing.","ALL","2 Years","7 Years",{"count":62,"type":63},60,"ESTIMATED","INTERVENTIONAL",[66],"NA","This study aims to evaluate if adding dexmedetomidine to bupivacaine in a caudal block can provide longer and better quality pain relief for children after open appendectomy surgery. The study will also assess the effect of this combination on the quality of recovery, including the incidence of emergence delirium, and its overall safety profile.",[69,70],"Appendectomy","Pediatric",[72,73,74],"caudal","dexmedetomidine","open appendectomy","2026-04-30",{"date":77,"type":78},"2026-05-06","ACTUAL",{"date":80,"type":78},"2025-08-01",{"date":82,"type":63},"2026-07-30",{"name":5,"class":6},1]