[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618325":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":39,"centralContacts":47,"locations":55,"responsibleParty":74,"collaborators":77,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":51,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":51,"enrollmentInfo":89,"targetDuration":51,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":101,"overallStatus":58,"whyStopped":51,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"King Abdullah University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Nano bio-fusion gingival gel (NBF)","EXPERIMENTAL","The gel should be applied 4 times daily for 4 weeks. After drying the surgical site in the palate with a sterile gauze, a pea size of the gel material is applied to the wound using cotton applicator. If there is a vertical relasing incision in the recipient site, the gel will be applied using the same technique.",[13],"Drug: Application of NBF gel after soft tissue graft surgery",{"label":15,"type":16,"description":11,"interventionNames":17},"placebo gel","PLACEBO_COMPARATOR",[18],"Other: Application of placebo gel after soft tissue graft surgery",[20,34],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Application of NBF gel after soft tissue graft surgery","After the surgery, patients will be instructed to apply the NBF gel to the donor site on the palate for four times daily for 4 weeks. If there is a vertical releasing incision in the recipient site, the gel will be applied along that incision too. The first application will be performed immediately after surgery by the investigator using a sterile cotton applicator.",[9],[26,27,28,29,30,31,32,33],"phenotype modification","recession coverage","free gingival graft","connective tissue graft","coronal position flap","subepithelial connective tissue graft","tunnelling","lateral position flap",{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":38},"Application of placebo gel after soft tissue graft surgery","After the surgery, patients will be instructed to apply the placebo gel to the donor site on the palate for four times daily for 4 weeks. If there is a vertical releasing incision in the recipient site, the gel will be applied along that incision too. The first application will be performed immediately after surgery by the investigator using a sterile cotton applicator.",[15],[26,27,28,29,30,31,32,33],[40,44],{"name":41,"affiliation":42,"role":43},"Lana Bader, DClinDent Perio","Jordan University of Science and Technology","STUDY_DIRECTOR",{"name":45,"affiliation":42,"role":46},"Rand Aldurra, MClinDent Perio","PRINCIPAL_INVESTIGATOR",[48,53],{"name":41,"role":49,"phone":50,"phoneExt":51,"email":52},"CONTACT","+962791200956",null,"lmbader4@just.edu.jo",{"name":45,"role":49,"phone":51,"phoneExt":51,"email":54},"lana.bader@yahoo.com",[56],{"facility":57,"status":58,"city":59,"state":60,"zip":61,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"Jordan University of Science and Technology, Faculty of Dentistry","RECRUITING","Irbid","Irbid Governorate","22110","Jordan","JO",{"type":65,"coordinates":66},"Point",[67,68],35.85,32.55556,{"lat":68,"lon":67},[71,72],{"name":41,"role":49,"phone":50,"phoneExt":51,"email":52},{"name":45,"role":49,"phone":51,"phoneExt":51,"email":73},"raaldurrah23@den.just.edu.jo",{"type":46,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":51,"oldOrganization":51},"Lana Bader","assistant professor",[78],{"name":42,"class":6},"100618325","the-effectiveness-of-nano-bio-fusion-gingival-gel-nbf-on-wound-healing-at-the-palate-donor-site-after-soft-tissue-graft-surgery-compared-to-placebo-gel-100618325",false,"NCT07330154","The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.","The Effectiveness of Nano Bio Fusion Gel (NBF) on Early Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel: a Double Blinded Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n1. Patients with gingival recession that is indicated for root coverage or need for phenotype modification.\n2. 18 years or older.\n3. absence of systemic disease\n4. Non-smoker\n5. No use of antibiotics, corticosteroids, anti-inflammatory medication or hormones in the past 3 months\n\nExclusion Criteria:\n\n1. Pregnant or lactating woman.\n2. patients with immune or systemic diseases.\n3. Patients with an allergy to any ingredient in the gel.",true,"ALL","18 Years",{"count":90,"type":91},36,"ESTIMATED","INTERVENTIONAL",[94],"NA","The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel. The main questions it aims to answer are:\n\n* Does NBF gel enhance wound healing after graft harvesting from the palate?\n* Does NBF gel reduce the number of inflammatory mediators after surgery?\n* Does NBF gel reduce pain and discomfort at the palatal donor site? Researchers will compare NBF gel to a placebo (a look-alike gel that does not contain the active ingredients) to see if NBF gel enhances wound healing.\n\nStudy steps include:\n\n* Participants will apply the assigned gel on the surgical wound 4 times a day for 4 weeks.\n* Clinical photographs and measurements will be obtained on days (0, 1, 2, 4, 7, 15, 21, 30).\n* Wound fluid samples will be collected on days (0, 1, 2, 4, 7).\n* Participants will be asked about the level of pain and analgesic consumption on each follow-up visit.",[97,98,99,100],"Wound Healing","Palatal Wound","Donor Site Complication","Inflammatory Cytokines",[102,103,104,105],"NBF gel","wound healing","palatal donor site","soft tissue graft","2026-01-21",{"date":108,"type":109},"2026-01-23","ACTUAL",{"date":111,"type":109},"2025-10-29",{"date":113,"type":91},"2026-12",{"name":5,"class":6},1]